Rabbit Anti-CPT1C Polyclonal Antibody – Cat# MBS9203315

CPT1C Antibody (C-term) western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the CPT1C antibody detected the CPT1C protein (arrow).

CPT1C Antibody – Rabbit Polyclonal

Name: CPT1C Antibody; Polyclonal; Rabbit; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS9203315
Price: 240 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS9203315

The Cpt1 family of proteins are outer mitochondrial membrane proteins that regulate the entry into, and oxidation of fatty acids by, mitochondria. Malonyl-CoA, an intermediate in fatty acid synthesis, has been implicated as a regulatory component of the… More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

CPT1C, Polyclonal Antibody

Full Product Name

CPT1C Antibody (C-term)

Product Gene Name

anti-CPT1C antibody

Product Synonym Names

Carnitine O-palmitoyltransferase 1; brain isoform; CPT1-B; CPT IC; Carnitine O-palmitoyltransferase I; brain isoform; CPTI-B; Carnitine palmitoyltransferase 1C; CPT1C; CATL1

Clonality

Polyclonal

Isotype

Rabbit Ig

Host

Rabbit

Species Reactivity

Human

Form/Format

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Purity/Purification

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Concentration

Vial Concentration: 0.4 (lot specific)

Specificity

This CPT1C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 596-625 amino acids from the C-terminal region of human CPT1C.

Preparation and Storage

Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.

Antibody/Peptide Pairs

CPT1C peptide (MBS9221506) is used for blocking the activity of CPT1C antibody (MBS9203315)

Molecular Weight

90989

Immunogen Sequence Positions

596-625

OMIM

608846

3D Structure

ModBase 3D Structure for Q8TCG5

Antigen Type

Synthetic Peptide

Antigen Source

HUMAN

Product Categories/Family for anti-CPT1C antibody

Cardiovascular; Metabolism; Neuroscience; Signal Transduction

Applications Tested/Suitable for anti-CPT1C antibody

Western Blot (WB), ELISA (EIA)

Application Notes for anti-CPT1C antibody

WB~~1:1000

Product References and Citations for anti-CPT1C antibody

Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
Roomets, E., et al. Invest. Ophthalmol. Vis. Sci. 49(4):1660-1664(2008)
Sierra, A.Y., et al. J. Biol. Chem. 283(11):6878-6885(2008)
Price, N., et al. Genomics 80(4):433-442(2002)

Other Notes

Small volumes of anti-CPT1C antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CPT1C purchase

MBS9203315 is an antibody targeting CPT1C. Also known as CPT1C Antibody (C-term). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for CPT1C. It may not necessarily be applicable to this product.

NCBI GI #

209862905

NCBI GeneID

126129

NCBI Accession #

NP_001129524.1

NCBI Related Accession #

NP_001186681.1; NP_001186682.1; NP_689572.1

UniProt Primary Accession #

Q8TCG5

UniProt Secondary Accession #

Q5K6N5; Q8N6Q9; Q8NDS6; Q8TE84; A8K0Z8

UniProt Related Accession #

Q8TCG5

GenBank Nucleotide #

NM_001136052.2

NCBI Official Full Name

carnitine O-palmitoyltransferase 1, brain isoform isoform 1

NCBI Official Synonym Full Names

carnitine palmitoyltransferase 1C

NCBI Official Symbol

CPT1C

NCBI Official Synonym Symbols

CATL1; CPT1P; CPTIC; SPG73; CPT1-B; CPTI-B

UniProt Protein Name

Carnitine O-palmitoyltransferase 1, brain isoform

UniProt Synonym Protein Names

CPT IC; Carnitine O-palmitoyltransferase I, brain isoform; CPTI-B; Carnitine palmitoyltransferase 1C

Protein Family

Carnitine O-palmitoyltransferase

UniProt Gene Name

CPT1C

UniProt Synonym Gene Names

CATL1; CPT1-B; CPTI-B

UniProt Entry Name

CPT1C_HUMAN

NCBI Protein Information

carnitine O-palmitoyltransferase 1, brain isoform

NCBI Summary for CPT1C

This gene encodes a member of the carnitine/choline acetyltransferase family. The encoded protein regulates the beta-oxidation and transport of long-chain fatty acids into mitochondria, and may play a role in the regulation of feeding behavior and whole-body energy homeostasis. Alternatively spliced transcript variants encoding multiple protein isoforms have been observed for this gene. [provided by RefSeq, Dec 2010]

UniProt Comments for CPT1C

CPT1C: a member of the carnitine/choline acetyltransferase family. The encoded protein regulates the beta-oxidation and transport of long-chain fatty acids into mitochondria, and may play a role in the regulation of feeding behavior and whole-body energy homeostasis. Alternatively spliced transcript variants encoding multiple protein isoforms have been observed for this gene. [provided by RefSeq, Dec 2010]

Protein type: Transferase; Membrane protein, multi-pass; Lipid Metabolism - fatty acid; Membrane protein, integral; EC 2.3.1.21

Chromosomal Location of Human Ortholog: 19q13.33

Cellular Component: endoplasmic reticulum membrane; mitochondrial outer membrane; synapse; cell junction

Molecular Function: carnitine O-palmitoyltransferase activity

Biological Process: fatty acid beta-oxidation; carnitine metabolic process

Disease: Spastic Paraplegia 73, Autosomal Dominant

Research Articles on CPT1C

1. High grade glioblastoma is associated with increased level of ZFP57, a protein involved in gene imprinting, and aberrant expression of CPT1A and CPT1C.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-CPT1C antibody

Reference Product	PubMed Publications
CPT1B antibody	>10 publications with CPT1C and CPT1B
CPT2 antibody	>2 publications with CPT1C and CPT2

Diseases associated with anti-CPT1C antibody

Disease Name	Pubmed Publications
Nervous System Diseases Antibodies	>9 publications with CPT1C and Nervous System Diseases
Fatty Liver Antibodies	>8 publications with CPT1C and Fatty Liver
Weight Gain Antibodies	>5 publications with CPT1C and Weight Gain
Breast Neoplasms Antibodies	>2 publications with CPT1C and Breast Neoplasms
Peripheral Nervous System Diseases Antibodies	>2 publications with CPT1C and Peripheral Nervous System Diseases
Liver Diseases Antibodies	>2 publications with CPT1C and Liver Diseases
Prenatal Injuries Antibodies	>1 publications with CPT1C and Prenatal Injuries
Inflammation Antibodies	>1 publications with CPT1C and Inflammation
Neoplasms, Experimental Antibodies	>1 publications with CPT1C and Neoplasms, Experimental
Learning Disorders Antibodies	>1 publications with CPT1C and Learning Disorders

Organs/Tissues associated with anti-CPT1C antibody

Organ/Tissue Name	Pubmed Publications
Brain Antibodies	>29 publications with CPT1C and Brain
Eye Antibodies	>4 publications with CPT1C and Eye
Nerve Antibodies	>1 publications with CPT1C and Nerve
Lung Antibodies	>1 publications with CPT1C and Lung
Uterus Antibodies	>1 publications with CPT1C and Uterus
Heart Antibodies	>1 publications with CPT1C and Heart