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DBI Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS9443902

This gene encodes diazepam binding inhibitor, a protein that is regulated by hormones and is involved in lipid metabolism and the displacement of beta-carbolines and benzodiazepines, which modulate signal transduction at type A gamma-aminobutyric acid… More details

$435 / 0.1 mL (Biotin) +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
DBI, Polyclonal Antibody
Full Product Name
DBI Conjugated Antibody
Product Gene Name
anti-DBI antibody
Product Synonym Names
EP; ACBP; ACBD1; CCK-RP
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human
Form/Format
0.01M Sodium Phosphate, 0.25M NaCl, pH 7.6, 5mg/ml Bovine Serum Albumin, 0.02% Sodium Azide
Specificity
The antibody detects endogenous level of total DBI protein.
Preparation and Storage
Store at 4 degree C for 6 months.
Molecular Weight
87
OMIM
125950
3D Structure
ModBase 3D Structure for P07108
Immunogen
Recombinant protein of human DBI.
Conjugation
Biotin AF350 AF405 AF488 AF555 AF594 AF647 AF680 AF750
Excitation Emission
AF350: 346nm/442nm
Applications Tested/Suitable for anti-DBI antibody
Most Applications
Application Notes for anti-DBI antibody
Suggested Dilution:
AF350 conjugated: most applications: 1:50-1:250
AF405 conjugated: most applications: 1:50-1:250
AF488 conjugated: most applications: 1:50-1:250
AF555 conjugated: most applications: 1:50-1:250
AF594 conjugated: most applications: 1:50-1:250
AF647 conjugated: most applications: 1:50-1:250
AF680 conjugated: most applications: 1:50-1:250
AF750 conjugated: most applications: 1:50-1:250
Biotin conjugated: working with enzyme-conjugated streptavidin, most applications: 1:50-1:1000

Other Notes

Small volumes of anti-DBI antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for DBI purchase

MBS9443902 is an antibody targeting DBI. Also known as DBI Conjugated Antibody. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for DBI. It may not necessarily be applicable to this product.

NCBI GI #
118276
NCBI GeneID
1622
NCBI Accession #
P07108.2
UniProt Primary Accession #
P07108
UniProt Secondary Accession #
P08869; Q4VWZ6; Q53SQ7; Q6IB48; Q9UCI8; B8ZWD2; B8ZWD6; B8ZWD7
UniProt Related Accession #
P07108
NCBI Official Full Name
Acyl-CoA-binding protein
NCBI Official Synonym Full Names
diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein)
NCBI Official Symbol
DBI
NCBI Official Synonym Symbols
EP; ACBP; ACBD1; CCK-RP
UniProt Protein Name
Acyl-CoA-binding protein
UniProt Synonym Protein Names
Diazepam-binding inhibitor; DBI; Endozepine; EP
Protein Family
Acyl-CoA-binding protein
UniProt Gene Name
DBI
UniProt Synonym Gene Names
ACBP; DBI; EP
UniProt Entry Name
ACBP_HUMAN
NCBI Protein Information
acyl-CoA-binding protein; endozepine; GABA receptor modulator; diazepam-binding inhibitor; acyl coenzyme A binding protein; acyl-Coenzyme A binding domain containing 1; cholecystokinin-releasing peptide, trypsin-sensitive; diazepam binding inhibitor (GABA

UniProt Comments for DBI

DBI: Binds medium- and long-chain acyl-CoA esters with very high affinity and may function as an intracellular carrier of acyl-CoA esters. It is also able to displace diazepam from the benzodiazepine (BZD) recognition site located on the GABA type A receptor. It is therefore possible that this protein also acts as a neuropeptide to modulate the action of the GABA receptor. Belongs to the ACBP family. 6 isoforms of the human protein are produced by alternative promoter.

Protein type: Lipid-binding

Chromosomal Location of Human Ortholog: 2q12-q21

Cellular Component: Golgi apparatus; mitochondrion; endoplasmic reticulum

Molecular Function: protein dimerization activity; benzodiazepine receptor binding; lipid binding

Biological Process: learning and/or memory; protein palmitoylation; triacylglycerol metabolic process; behavioral fear response; hair follicle development; transport; lateral ventricle development
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Research Articles on DBI

1. There was a significant difference in the rs2276596 polymorphism C/A allele frequency of the DBI gene (P < 0.0001) between alcoholics and healthy controls.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-DBI antibody

 Reference Product  PubMed Publications
 TSPO antibody  >6 publications with DBI and TSPO
 CCK antibody  >5 publications with DBI and CCK
 STAR antibody  >2 publications with DBI and STAR
 PPARG antibody  >2 publications with DBI and PPARG

Pathways associated with anti-DBI antibody

 Products by Pathway  Pathway Diagram
 PPAR Signaling Pathway antibodies  PPAR Signaling Pathway Diagram
 PPAR Signaling Pathway antibodies  PPAR Signaling Pathway Diagram
 SREBP Signalling Pathway antibodies  SREBP Signalling Pathway Diagram

Diseases associated with anti-DBI antibody

 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >77 publications with DBI and Nervous System Diseases
 Disease Models, Animal Antibodies  >30 publications with DBI and Disease Models, Animal
 Hemorrhage Antibodies  >15 publications with DBI and Hemorrhage
 Liver Diseases Antibodies  >14 publications with DBI and Liver Diseases
 Necrosis Antibodies  >8 publications with DBI and Necrosis
 Neoplasms, Experimental Antibodies  >8 publications with DBI and Neoplasms, Experimental
 Hepatic Encephalopathy Antibodies  >7 publications with DBI and Hepatic Encephalopathy
 Edema Antibodies  >7 publications with DBI and Edema
 Kidney Diseases Antibodies  >7 publications with DBI and Kidney Diseases
 Carcinoma Antibodies  >7 publications with DBI and Carcinoma

Organs/Tissues associated with anti-DBI antibody

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >202 publications with DBI and Brain
 Blood Antibodies  >97 publications with DBI and Blood
 Nerve Antibodies  >35 publications with DBI and Nerve
 Liver Antibodies  >34 publications with DBI and Liver
 Vascular Antibodies  >31 publications with DBI and Vascular
 Adrenal Gland Antibodies  >23 publications with DBI and Adrenal Gland
 Kidney Antibodies  >19 publications with DBI and Kidney
 Testis Antibodies  >18 publications with DBI and Testis
 Heart Antibodies  >15 publications with DBI and Heart
 Muscle Antibodies  >14 publications with DBI and Muscle
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