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DEDD2 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS8557792

MBS8557792 is an antibody targeting DEDD2. Also known as DEDD2 (Center) Rabbit pAb. Reactive in Human. Host: Rabbit. More details

$380 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
DEDD2, Polyclonal Antibody
Full Product Name
DEDD2 (Center) Rabbit pAb
Product Gene Name
anti-DEDD2 antibody
Product Synonym Names
DNA-binding death effector domain-containing protein 2; DED-containing protein FLAME-3; FADD-like anti-apoptotic molecule 3; DEDD2; FLAME3
Clonality
Polyclonal
Isotype
Ig
Host
Rabbit
Species Reactivity
Human
Form/Format
In PBS supplemented with 0.09% (W/V) Sodium Azide.
Purity/Purification
Affinity Purified
3D Structure
ModBase 3D Structure for Q8WXF8
Immunogen
This DEDD2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 162-193 amino acids from the central region of human DEDD2.
Cellular Localization
Nucleus
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-DEDD2 antibody
Western Blot (WB)
Application Notes for anti-DEDD2 antibody
WB: 1:2000

Other Notes

Small volumes of anti-DEDD2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for DEDD2. It may not necessarily be applicable to this product.

NCBI GI #
19923050
NCBI Accession #
NP_579874
UniProt Primary Accession #
Q8WXF8
GenBank Nucleotide #
NP_579874.1
NCBI Official Full Name
DNA-binding death effector domain-containing protein 2 isoform 1
UniProt Protein Name
DNA-binding death effector domain-containing protein 2
UniProt Synonym Protein Names
DED-containing protein FLAME-3; FADD-like anti-apoptotic molecule 3
Protein Family
DNA-binding death effector domain-containing protein
UniProt Gene Name
DEDD2
UniProt Synonym Gene Names
FLAME3
UniProt Entry Name
DEDD2_HUMAN

UniProt Comments for DEDD2

DEDD2: May play a critical role in death receptor-induced apoptosis and may target CASP8 and CASP10 to the nucleus. May regulate degradation of intermediate filaments during apoptosis. May play a role in the general transcription machinery in the nucleus and might be an important regulator of the activity of GTF3C3. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Nucleolus

Chromosomal Location of Human Ortholog: 19q13.2

Cellular Component: nucleoplasm; nucleolus

Molecular Function: protein binding; receptor signaling complex scaffold activity; DNA binding

Biological Process: RNA processing; induction of apoptosis via death domain receptors; transcription, DNA-dependent; apoptotic nuclear changes; rRNA catabolic process; cellular homeostasis; negative regulation of transcription, DNA-dependent
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-DEDD2 antibody

 Reference Product  PubMed Publications
 DEDD antibody  >7 publications with DEDD2 and DEDD
 CASP8 antibody  >7 publications with DEDD2 and CASP8
 FADD antibody  >6 publications with DEDD2 and FADD
 CASP10 antibody  >4 publications with DEDD2 and CASP10
 CFLAR antibody  >2 publications with DEDD2 and CFLAR
 GTF3C3 antibody  >1 publications with DEDD2 and GTF3C3

Diseases associated with anti-DEDD2 antibody

 Disease Name  Pubmed Publications
 Death Antibodies  >9 publications with DEDD2 and Death
 Necrosis Antibodies  >3 publications with DEDD2 and Necrosis
 Carcinoma, Hepatocellular Antibodies  >2 publications with DEDD2 and Carcinoma, Hepatocellular
 Liver Diseases Antibodies  >2 publications with DEDD2 and Liver Diseases
 Fatty Liver Antibodies  >1 publications with DEDD2 and Fatty Liver

Organs/Tissues associated with anti-DEDD2 antibody

 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >3 publications with DEDD2 and Liver
 Blood Antibodies  >1 publications with DEDD2 and Blood
 Placenta Antibodies  >1 publications with DEDD2 and Placenta
 Kidney Antibodies  >1 publications with DEDD2 and Kidney
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