• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

DND1 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS9211268

This gene encodes a protein that binds tomicroRNA-targeting sequences of mRNAs, inhibiting microRNA-mediatedrepression. Reduced expression of this gene has been implicated intongue squamous cell carcinoma. Two pseudogenes of this gene arelocated on the long… More details

$240 / 0.08 mL +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
DND1, Polyclonal Antibody
Full Product Name
DND1 Antibody (Center)
Product Gene Name
Product Synonym Names
Dead end protein homolog 1; RNA-binding motif; single-stranded-interacting protein 4; DND1; RBMS4
Clonality
Polyclonal
Isotype
Rabbit Ig
Host
Rabbit
Species Reactivity
Human
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Concentration
Vial Concentration: 0.5 (lot specific)
Specificity
This DND1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 198-226 amino acids from the Central region of human DND1.
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Antibody/Peptide Pairs
DND1 peptide (MBS9221784) is used for blocking the activity of DND1 antibody (MBS9211268)
Molecular Weight
38687
Immunogen Sequence Positions
198-226
OMIM
609385
3D Structure
ModBase 3D Structure for Q8IYX4
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN
Applications Tested/Suitable for anti-DND1 antibody
Western Blot (WB), ELISA (EIA)
Application Notes for anti-DND1 antibody
WB~~1:1000

Western Blot (WB) of anti-DND1 antibody

DND1 Antibody (Center) western blot analysis in Hela cell line lysates (35ug/lane).This demonstrates the DND1 antibody detected the DND1 protein (arrow).
Rabbit Anti-DND1 Polyclonal Antibody – Cat# MBS9211268

Product References and Citations for anti-DND1 antibody

Liu, X., et al. FEBS Lett. 584(18):4115-4120(2010)
Sijmons, R.H., et al. Fam. Cancer 9(3):439-442(2010)
Kedde, M., et al. Cell Cycle 7(7):899-903(2008)
Linger, R., et al. Genes Chromosomes Cancer 47(3):247-252(2008)
Ketting, R.F. Cell 131(7):1226-1227(2007)

Other Notes

Small volumes of anti-DND1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for DND1 purchase

MBS9211268 is an antibody targeting DND1. Also known as DND1 Antibody (Center). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for DND1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
dead end protein homolog 1
NCBI Official Synonym Full Names
DND microRNA-mediated repression inhibitor 1
NCBI Official Symbol
DND1
NCBI Official Synonym Symbols
RBMS4
UniProt Protein Name
Dead end protein homolog 1
UniProt Synonym Protein Names
RNA-binding motif, single-stranded-interacting protein 4
Protein Family
UniProt Gene Name
DND1
UniProt Synonym Gene Names
RBMS4
UniProt Entry Name
DND1_HUMAN
NCBI Protein Information
dead end protein homolog 1

NCBI Summary for DND1

This gene encodes a protein that binds to microRNA-targeting sequences of mRNAs, inhibiting microRNA-mediated repression. Reduced expression of this gene has been implicated in tongue squamous cell carcinoma. Two pseudogenes of this gene are located on the long arm of chromosome 17. [provided by RefSeq, Dec 2010]
Show more

UniProt Comments for DND1

DND1: RNA-binding factor that positively regulates gene expression by prohibiting miRNA-mediated gene suppression. Relieves miRNA repression in germline cells. Prohibits the function of several miRNAs by blocking the accessibility of target mRNAs. Sequence-specific RNA-binding factor that binds specifically to U-rich regions (URRs) in the 3' untranslated region (3'-UTR) of several mRNAs. Does not bind to miRNAs. May play a role during primordial germ cell (PGC) survival. However, does not seem to be essential for PGC migration.

Chromosomal Location of Human Ortholog: 5q31.3

Cellular Component: cytoplasm; nucleus

Molecular Function: miRNA binding; nucleotide binding; AU-rich element binding

Biological Process: multicellular organismal development; germ cell development
Show more

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000