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DOCK11 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3902106

DOCK11 (dedicator of cytokinesis 11) is also known as zizimin-2. It is a DOCK180-related guanine nucleotide exchange factor (GEF) for the small GTPase, Cdc42. As a GEF, DOCK11 functions to catalyze the dissociation of GDP from the GTPase. Dissociation of GDP… More details

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Product Overview

Online Datasheet in PDF
Product Name
DOCK11, Polyclonal Antibody
Full Product Name
Rabbit anti-DOCK11 Antibody, Affinity Purified
Product Gene Name
Product Synonym Names
dedicator of cytokinesis protein 11; zizimin-2; zizimin2; ZIZ2; bB128O4.1.1 (novel protein); bB128O4.1; Activated Cdc42-associated guanine nucleotide exchange factor, ACG; ACG; Activated Cdc42-associated guanine nucleotide exchange factor; Dedicator of cytokinesis protein 11; dedicator of cytokinesis 11
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human
Form/Format
Liquid. Whole IgG. Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide
Purity/Purification
Antigen Affinity Purified
Concentration
1000ug/ml (lot specific)
Preparation and Storage
Store at 2-8 degree C
Shelf Life: 1 year from date of receipt
Molecular Weight
237,671 Da
OMIM
300681
3D Structure
ModBase 3D Structure for Q5JSL3
Predicted Reactivity
Mouse
Immunogen
Between 125 and 175
Conjugation
Unconjugated

Product Categories/Family for anti-DOCK11 antibody

Applications Tested/Suitable for anti-DOCK11 antibody
Immunoprecipitation (IP)
Application Notes for anti-DOCK11 antibody
IP: 6ug/mg lysate

Immunoprecipitation (IP) of anti-DOCK11 antibody

Detection of human DOCK11 by western blot of immunoprecipitates. Samples: Whole cell lysate (1.0 mg per IP reaction; 20% of IP loaded) from HeLa cells prepared using NETN lysis buffer. Antibodies: Affinity purified rabbit anti-DOCK11 antibody MBS3902106 (lot MBS3902106-2) used for IP at 3 ug per reaction. DOCK11 was also immunoprecipitated by rabbit anti-DOCK11 antibody MBS3902107. For blotting immunoprecipitated DOCK11, MBS3902106 was used at 0.4 ug/ml. Detection: Chemiluminescence with an exposure time of 10 seconds.
Rabbit Anti-DOCK11 Polyclonal Antibody – Cat# MBS3902106

Other Notes

Small volumes of anti-DOCK11 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for DOCK11 purchase

MBS3902106 is an antibody targeting DOCK11. Also known as Rabbit anti-DOCK11 Antibody, Affinity Purified. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for DOCK11. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
dedicator of cytokinesis protein 11
NCBI Official Synonym Full Names
dedicator of cytokinesis 11
NCBI Official Symbol
DOCK11
NCBI Official Synonym Symbols
ACG; ZIZ2; bB128O4.1
UniProt Protein Name
Dedicator of cytokinesis protein 11
UniProt Synonym Protein Names
Activated Cdc42-associated guanine nucleotide exchange factor; ACG; Zizimin-2
UniProt Gene Name
DOCK11
UniProt Synonym Gene Names
ZIZ2; ACG
UniProt Entry Name
DOC11_HUMAN
NCBI Protein Information
dedicator of cytokinesis protein 11; zizimin2; zizimin-2; bB128O4.1.1 (novel protein); Activated Cdc42-associated guanine nucleotide exchange factor, ACG

UniProt Comments for DOCK11

DOCK11: Guanine nucleotide-exchange factor (GEF) that activates CDC42 by exchanging bound GDP for free GTP. Belongs to the DOCK family.

Protein type: GEFs; GEFs, Rac/Rho; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: Xq24

Cellular Component: cytosol

Molecular Function: Rho guanyl-nucleotide exchange factor activity; Rho GTPase binding

Biological Process: small GTPase mediated signal transduction; blood coagulation
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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