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DTX4 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS623677

DTX4 is a regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations More details

$895 / 0.2 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
DTX4, Polyclonal Antibody
Full Product Name
DTX4, NT (RING Finger Protein 155, Protein Deltex-4, Deltex4, KIAA0937, RNF155)
Product Gene Name
Product Synonym Names
Anti -DTX4, NT (RING Finger Protein 155, Protein Deltex-4, Deltex4, KIAA0937, RNF155)
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, 0.09% sodium azide.
Purity/Purification
Affinity Purified
Purified by immunoaffinity chromatography.
Specificity
Recognizes human DTX4.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
67,258 Da
Chromosome Location
Chromosome: 11; NC_000011.9 (58939812..58976060). Location: 11q12.1
3D Structure
ModBase 3D Structure for Q9Y2E6
Immunogen
Synthetic peptide selected from the N-terminal region of human DTX4 (KLH).
Applications Tested/Suitable for anti-DTX4 antibody
ELISA (EL/EIA), Western Blot (WB)
Application Notes for anti-DTX4 antibody
Suitable for use in ELISA and Western Blot.
Dilution: ELISA: 1:1,000
Western Blot: 1:100-1:500

Western Blot (WB) of anti-DTX4 antibody

Western Blot analysis in HL-60 cell line lysates (35ug/lane) using MBS623677. DTX4 (arrow) was detected using MBS623677.
Rabbit Anti-DTX4 Polyclonal Antibody – Cat# MBS623677

Immunohistochemistry (IHC) of anti-DTX4 antibody

Immunohistochemistry in formalin-fixed and paraffin-embedded human brain tissue reacted using MBS623677, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of MBS623677 for immunohistochemistry.
Rabbit Anti-DTX4 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS623677

Testing Data of anti-DTX4 antibody

Rabbit Anti-DTX4 Polyclonal Antibody, Testing Data – Cat# MBS623677

Other Notes

Small volumes of anti-DTX4 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for DTX4 purchase

MBS623677 is an antibody targeting DTX4. Also known as DTX4, NT (RING Finger Protein 155, Protein Deltex-4, Deltex4, KIAA0937, RNF155). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for DTX4. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
DTX4 protein
NCBI Official Synonym Full Names
deltex homolog 4 (Drosophila)
NCBI Official Symbol
DTX4
NCBI Official Synonym Symbols
RNF155; KIAA0937; MGC141899
UniProt Protein Name
Protein deltex-4
UniProt Synonym Protein Names
RING finger protein 155
UniProt Gene Name
DTX4
UniProt Synonym Gene Names
KIAA0937; RNF155
UniProt Entry Name
DTX4_HUMAN
NCBI Protein Information
protein deltex-4; deltex4; deltex 4 homolog; OTTHUMP00000235742; OTTHUMP00000235743; RING finger protein 155

UniProt Comments for DTX4

DTX4: Regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations. Functions as an ubiquitin ligase protein in vivo, mediating 'Lys48'-linked polyubiquitination and promoting degradation of TBK1, targeting to TBK1 requires interaction with NLRP4. Belongs to the Deltex family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 6.3.2.-; Ubiquitin conjugating system

Chromosomal Location of Human Ortholog: 11q12.1

Cellular Component: cytosol

Molecular Function: zinc ion binding; ligase activity

Biological Process: regulation of interferon type I production; Notch signaling pathway; positive regulation of interferon type I production; innate immune response; protein ubiquitination
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-DTX4 antibody

Diseases associated with anti-DTX4 antibody

 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >1 publications with DTX4 and Neoplasms

Organs/Tissues associated with anti-DTX4 antibody

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >1 publications with DTX4 and Blood
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