Rabbit Anti-DUSP9 Polyclonal Antibody – Cat# MBS3219713

WB Suggested Anti-DUS9 antibody Titration: 1 ug/mL
Sample Type: Human 293T Whole Cell

DUSP9 Antibody – Rabbit Polyclonal

Name: DUSP9 Antibody; Polyclonal; Rabbit; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS3219713
Price: 490 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3219713

This is a rabbit polyclonal antibody against DUS9. It was validated on Western BlotTarget Description: The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by… More details

$490 / 0.1 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

DUSP9, Polyclonal Antibody

Full Product Name

DUSP9 Antibody - C-terminal region

Product Gene Name

anti-DUSP9 antibody

Product Synonym Gene Name

MKP4; MKP-4;

Immunogen Sequence

Synthetic peptide located within the following region: NFNFMGQLLD FERSLRLEER HSQEQGSGGQ ASAASNPPSF FTTPTSDGAF

Clonality

Polyclonal

Host

Rabbit

Species Reactivity

Human

Form/Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Purity/Purification

Affinity purified

Preparation and Storage

For short term use, store at 2-8 degree C up to 1 week. For long term storage, store at -20 degree C in small aliquots to prevent freeze-thaw cycles.

Antibody/Peptide Pairs

DUSP9 peptide (MBS3244578) is used for blocking the activity of DUSP9 antibody (MBS3219713)

Molecular Weight

42 kDa

OMIM

300134

3D Structure

ModBase 3D Structure for Q99956

Immunogen

The immunogen for Anti-DUSP9 antibody is: synthetic peptide directed towards the C-terminal region of Human DUS9

Product Categories/Family for anti-DUSP9 antibody

Polyclonal; Membrane Protein; Developmental Biology; Meiosis/Mitosis/Cell Cycle

Applications Tested/Suitable for anti-DUSP9 antibody

Western Blot (WB)

Other Notes

Small volumes of anti-DUSP9 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for DUSP9 purchase

MBS3219713 is an antibody targeting DUSP9. Also known as DUSP9 Antibody - C-terminal region. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for DUSP9. It may not necessarily be applicable to this product.

NCBI GI #

530422743

NCBI GeneID

1852

NCBI Accession #

XP_005274712.1

UniProt Primary Accession #

Q99956

UniProt Related Accession #

Q99956

GenBank Nucleotide #

XM_005274655.2

NCBI Official Synonym Full Names

dual specificity phosphatase 9

NCBI Official Symbol

DUSP9

NCBI Official Synonym Symbols

MKP4; MKP-4

UniProt Protein Name

Dual specificity protein phosphatase 9

UniProt Synonym Protein Names

Mitogen-activated protein kinase phosphatase 4

Protein Family

Dual specificity protein phosphatase

UniProt Gene Name

DUSP9

UniProt Synonym Gene Names

MKP4; MAP kinase phosphatase 4; MKP-4

UniProt Entry Name

DUS9_HUMAN

NCBI Protein Information

dual specificity protein phosphatase 9

NCBI Summary for DUSP9

The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product shows selectivity for members of the ERK family of MAP kinases and is localized to the cytoplasm and nucleus. Aberrant expression of this gene is associated with type 2 diabetes and cancer progression in several cell types. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]

UniProt Comments for DUSP9

DUSP9: a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (ERK, JNK, p38). Shows selectivity for members of the ERK family, is expressed at high levels in placenta, kidney, and fetal liver, and is localized to the cytoplasm and nucleus.

Protein type: Motility/polarity/chemotaxis; EC 3.1.3.48; EC 3.1.3.16; Protein phosphatase, dual-specificity

Chromosomal Location of Human Ortholog: Xq28

Cellular Component: cytoplasm; nucleus

Molecular Function: protein binding; protein tyrosine/serine/threonine phosphatase activity; protein tyrosine phosphatase activity; MAP kinase tyrosine/serine/threonine phosphatase activity; phosphoprotein phosphatase activity

Biological Process: JNK cascade; protein amino acid dephosphorylation; inactivation of MAPK activity

Research Articles on DUSP9

1. The results of this study, combined with previous studies, suggested that therapeutic intervention to increase the expression or activity of DUSP9 may enable the activation of anti-proliferation signals in malignant cells.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

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Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.