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DZIP3 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS9233481

MBS9233481 is an antibody targeting DZIP3. Reactive in Human. Host: Rabbit. Rabbit polyclonal antibody to DZIP3 More details

$475 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
DZIP3, Polyclonal Antibody
Full Product Name
Anti-DZIP3 Antibody
Product Gene Name
Product Synonym Names
KIAA0675; E3 ubiquitin-protein ligase DZIP3; DAZ-interacting protein 3; RNA-binding ubiquitin ligase of 138 kDa; hRUL138
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 2 weeks. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Molecular Weight
138,604 Da
Chromosome Location
Chromosome: 3; NC_000003.11 (108308337..108413693). Location: 3q13.13
OMIM
608672
3D Structure
ModBase 3D Structure for Q86Y13
Applications Tested/Suitable for anti-DZIP3 antibody
Western Blot (WB), Immunohistochemistry (IHC)

Wester Blot (WB) of anti-DZIP3 antibody

Dilution: WB 1/500 - 1/1000
Western blot analysis of DZIP3 expression in HEK293T (A), LO2 (B) whole cell lysates.
Rabbit Anti-DZIP3 Polyclonal Antibody – Cat# MBS9233481

Immunohistochemistry (IHC) of anti-DZIP3 antibody

Dilution: IH 1/50 - 1/200
Immunohistochemical analysis of DZIP3 staining in human prostate cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.
Rabbit Anti-DZIP3 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS9233481

Other Notes

Small volumes of anti-DZIP3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for DZIP3. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
E3 ubiquitin-protein ligase DZIP3
NCBI Official Synonym Full Names
DAZ interacting zinc finger protein 3
NCBI Official Symbol
DZIP3
NCBI Official Synonym Symbols
UURF2; PPP1R66; hRUL138
UniProt Protein Name
E3 ubiquitin-protein ligase DZIP3
UniProt Synonym Protein Names
DAZ-interacting protein 3; RNA-binding ubiquitin ligase of 138 kDa
UniProt Gene Name
DZIP3
UniProt Synonym Gene Names
KIAA0675; hRUL138
UniProt Entry Name
DZIP3_HUMAN
NCBI Protein Information
E3 ubiquitin-protein ligase DZIP3; UURF2 ubiquitin ligase; DAZ-interacting protein 3; zinc finger DAZ interacting protein 3; DAZ interacting protein 3, zinc finger; RNA-binding ubiquitin ligase of 138 kDa; protein phosphatase 1, regulatory subunit 66; hum

UniProt Comments for DZIP3

DZIP3: E3 Ubiquitin ligase proteins mediate ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin- conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Able to specifically bind RNA. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: RNA-binding; Ligase; EC 6.3.2.-; Ubiquitin conjugating system; Ubiquitin ligase; EC 6.3.2.19

Chromosomal Location of Human Ortholog: 3q13.13

Cellular Component: cytoplasm

Molecular Function: protein binding; zinc ion binding; RNA binding; ubiquitin-protein ligase activity; polyubiquitin binding; ligase activity; phosphatase binding

Biological Process: protein polyubiquitination
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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