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EAPP Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6294155

This gene encodes a phosphoprotein that interacts with several members of the E2F family of proteins. The protein localizes to the nucleus, and is present throughout the cell cycle except during mitosis. It functions to modulate E2F-regulated transcription… More details

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Testing Data View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
EAPP, Polyclonal Antibody
Full Product Name
EAPP, CT (EAPP, C14orf11, E2F-associated phosphoprotein) (MaxLight 550)
Product Gene Name
anti-EAPP antibody
Product Synonym Names
EAPP; C14orf11; E2F-associated phosphoprotein
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight550.
Purity/Purification
Purified by Protein A Affinity Chromatography.
Preparation and Storage
Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: MaxLight550 conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molecular Weight
32,762 Da
OMIM
609486
3D Structure
ModBase 3D Structure for Q56P03
Immunogen
EAPP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 203-233 amino acids from the C-terminal region of human EAPP.
Conjugate
MaxLight550
Note
Preservative Free

Product Categories/Family for anti-EAPP antibody

Antibodies; KIAA; orf
Applications Tested/Suitable for anti-EAPP antibody
Immunohistochemistry (IHC), FLISA, Western Blot (WB)
Application Notes for anti-EAPP antibody
IHC: 1:10-50
FLISA: 1:1,000
WB: 1:100-500
Applications are based on unconjugated antibody.

Product References and Citations for anti-EAPP antibody

Schwarzmayr, L., et al. Int. J. Biochem. Cell Biol. 40(12):2845-2853(2008). Lamesch, P., et al. Genomics 89(3):307-315(2007). Olsen, J.V., et al. Cell 127(3):635-648(2006). Olsen, J.V., et al. Cell 127(3):635-648(2006). Lim, J., et al. Cell 125(4):801-814(2006).

Other Notes

Small volumes of anti-EAPP antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for EAPP purchase

MBS6294155 is an antibody targeting EAPP. Also known as EAPP, CT (EAPP, C14orf11, E2F-associated phosphoprotein) (MaxLight 550). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for EAPP. It may not necessarily be applicable to this product.

NCBI GI #
117938268
NCBI GeneID
55837
NCBI Accession #
NP_060923.2
UniProt Primary Accession #
Q56P03
UniProt Secondary Accession #
Q9BVF4; Q9NWV5; Q9NZ86
UniProt Related Accession #
Q56P03
GenBank Nucleotide #
NM_018453.3
NCBI Official Full Name
E2F-associated phosphoprotein
NCBI Official Synonym Full Names
E2F-associated phosphoprotein
NCBI Official Symbol
EAPP
NCBI Official Synonym Symbols
BM036; C14orf11
UniProt Protein Name
E2F-associated phosphoprotein
Protein Family
E2F-associated phosphoprotein
UniProt Gene Name
EAPP
UniProt Synonym Gene Names
C14orf11; EAPP
UniProt Entry Name
EAPP_HUMAN
NCBI Protein Information
E2F-associated phosphoprotein

UniProt Comments for EAPP

EAPP: May play an important role in the fine-tuning of both major E2F1 activities, the regulation of the cell-cycle and the induction of apoptosis. Promotes S-phase entry, and inhibits p14(ARP) expression. Interacts with E2F1. The C-terminal half binds the N- terminal of E2F1. Also interacts with E2F2 and E2F3, but not E2F4. Ubiquitously expressed. Highest levels in heart, placenta, skeletal muscle and pancreas. Lower levels in brain, lung and kidney. In the brain, expressed in all regions with high levels in the cerebellum and cerebral cortex. Expressed in COS1 and transformed skin fibroblasts.

Chromosomal Location of Human Ortholog: 14q13.1

Cellular Component: nucleoplasm; Golgi apparatus; cytoplasm; nucleus

Biological Process: positive regulation of RNA elongation from RNA polymerase II promoter; positive regulation of cell proliferation
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Research Articles on EAPP

1. Independently of EAPP, E2F1 also increases the activity of the MDR1 promoter.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-EAPP antibody

 Reference Product  PubMed Publications
 E2F4 antibody  >1 publications with EAPP and E2F4
 E2F2 antibody  >1 publications with EAPP and E2F2
 E2F3 antibody  >1 publications with EAPP and E2F3

Diseases associated with anti-EAPP antibody

 Disease Name  Pubmed Publications
 Inflammation Antibodies  >2 publications with EAPP and Inflammation
 Lung Diseases Antibodies  >1 publications with EAPP and Lung Diseases
 Carcinoma, Hepatocellular Antibodies  >1 publications with EAPP and Carcinoma, Hepatocellular
 Abnormalities, Multiple Antibodies  >1 publications with EAPP and Abnormalities, Multiple
 Immune System Diseases Antibodies  >1 publications with EAPP and Immune System Diseases
 Liver Neoplasms Antibodies  >1 publications with EAPP and Liver Neoplasms
 Prostatic Diseases Antibodies  >1 publications with EAPP and Prostatic Diseases

Organs/Tissues associated with anti-EAPP antibody

 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >3 publications with EAPP and Liver
 Bone Antibodies  >2 publications with EAPP and Bone
 Lung Antibodies  >2 publications with EAPP and Lung
 Blood Antibodies  >2 publications with EAPP and Blood
 Connective Tissue Antibodies  >1 publications with EAPP and Connective Tissue
 Brain Antibodies  >1 publications with EAPP and Brain
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