Rabbit Anti-EDC3 Polyclonal Antibody – Cat# MBS6294327

EDC3 Antibody (Center) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the EDC3 antibody detected the EDC3 protein (arrow).

EDC3 Antibody – Rabbit Polyclonal

Name: EDC3 Antibody; Polyclonal; Rabbit; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS6294327
Price: 1060 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6294327

EDC3 is associated with an mRNA-decapping complex required for removal of the 5-prime cap from mRNA prior to its degradation from the 5-prime end (Fenger-Gron et al., 2005 [PubMed 16364915]). More details

$1060 / 0.2 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

EDC3, Polyclonal Antibody

Full Product Name

EDC3, ID (EDC3, LSM16, YJDC, YJEFN2, Enhancer of mRNA-decapping protein 3, LSM16 homolog, YjeF N-terminal domain-containing protein 2, YjeF domain-containing protein 1) (FITC)

Product Gene Name

anti-EDC3 antibody

Product Synonym Names

EDC3; LSM16; YJDC; YJEFN2; Enhancer of mRNA-decapping protein 3; LSM16 homolog; YjeF N-terminal domain-containing protein 2; YjeF domain-containing protein 1

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human

Form/Format

Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Fluorescein Isothiocyanate (FITC).

Purity/Purification

Purified by Protein A Affinity Chromatography.

Preparation and Storage

Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: FITC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Molecular Weight

56,078 Da

OMIM

609842

3D Structure

ModBase 3D Structure for Q96F86

Immunogen

EDC3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 219-247 amino acids from the Central region of human EDC3.

Conjugate

FITC

Note

Preservative Free

Special Handling

Light sensitive

Product Categories/Family for anti-EDC3 antibody

Antibodies; RNA Binding Proteins

Applications Tested/Suitable for anti-EDC3 antibody

Western Blot (WB), FLISA

Application Notes for anti-EDC3 antibody

WB: 1:100-500
FLISA: 1:1,000
Applications are based on unconjugated antibody.

Product References and Citations for anti-EDC3 antibody

Tritschler, F., et al. Mol. Cell 33(5):661-668(2009). Ling, S.H., et al. Mol. Cell. Biol. 28(19):5965-5976(2008). Tritschler, F., et al. Mol. Cell. Biol. 27(24):8600-8611(2007). Sugiyama, N., et al. Mol. Cell Proteomics 6(6):1103-1109(2007). Rudolph, C., et al. Horm. Metab. Res. 39(5):322-335(2007).

Other Notes

Small volumes of anti-EDC3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for EDC3 purchase

MBS6294327 is an antibody targeting EDC3. Also known as EDC3, ID (EDC3, LSM16, YJDC, YJEFN2, Enhancer of mRNA-decapping protein 3, LSM16 homolog, YjeF N-terminal domain-containing protein 2, YjeF domain-containing protein 1) (FITC). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for EDC3. It may not necessarily be applicable to this product.

NCBI GI #

19923613

NCBI GeneID

80153

NCBI Accession #

NP_079359.2

UniProt Primary Accession #

Q96F86

UniProt Secondary Accession #

Q9H797; B3KPH0; D3DW61

UniProt Related Accession #

Q96F86

GenBank Nucleotide #

NM_025083.3

NCBI Official Full Name

enhancer of mRNA-decapping protein 3

NCBI Official Synonym Full Names

enhancer of mRNA decapping 3

NCBI Official Symbol

EDC3

NCBI Official Synonym Symbols

YJDC; LSM16; MRT50; YJEFN2

UniProt Protein Name

Enhancer of mRNA-decapping protein 3

UniProt Synonym Protein Names

LSM16 homolog; YjeF N-terminal domain-containing protein 2; YjeF_N2; hYjeF_N2; YjeF domain-containing protein 1

Protein Family

Enhancer of mRNA-decapping protein

UniProt Gene Name

EDC3

UniProt Synonym Gene Names

LSM16; YJDC; YJEFN2; YjeF_N2; hYjeF_N2

UniProt Entry Name

EDC3_HUMAN

NCBI Protein Information

enhancer of mRNA-decapping protein 3

Research Articles on EDC3

1. In vitro decapping assays showed that altered EDC3 is unable to enhance DCP2 decapping at low concentrations and even inhibits DCP2 decapping at high concentration.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-EDC3 antibody

Reference Product	PubMed Publications
DCP2 antibody	>27 publications with EDC3 and DCP2
XRN1 antibody	>10 publications with EDC3 and XRN1
LSM1 antibody	>8 publications with EDC3 and LSM1
EDC4 antibody	>7 publications with EDC3 and EDC4
DDX6 antibody	>6 publications with EDC3 and DDX6
LSM4 antibody	>2 publications with EDC3 and LSM4
PATL1 antibody	>1 publications with EDC3 and PATL1

Pathways associated with anti-EDC3 antibody

Products by Pathway	Pathway Diagram
Deadenylation-dependent MRNA Decay Pathway antibodies	Deadenylation-dependent MRNA Decay Pathway Diagram
Decapping Complex Pathway antibodies	Decapping Complex Pathway Diagram
Decapping Complex Pathway antibodies	Decapping Complex Pathway Diagram
Gene Expression Pathway antibodies	Gene Expression Pathway Diagram
RNA Degradation Pathway antibodies	RNA Degradation Pathway Diagram
RNA Degradation Pathway antibodies	RNA Degradation Pathway Diagram
MRNA Decay By 5' To 3' Exoribonuclease Pathway antibodies	MRNA Decay By 5' To 3' Exoribonuclease Pathway Diagram

Diseases associated with anti-EDC3 antibody

Disease Name	Pubmed Publications
Prostatic Neoplasms Antibodies	>1 publications with EDC3 and Prostatic Neoplasms
Nervous System Diseases Antibodies	>1 publications with EDC3 and Nervous System Diseases
Prostatic Diseases Antibodies	>1 publications with EDC3 and Prostatic Diseases
Inflammation Antibodies	>1 publications with EDC3 and Inflammation
Necrosis Antibodies	>1 publications with EDC3 and Necrosis