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eif3s10 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6004833

Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A,… More details

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Testing Data View PDF
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Material Safety Data Sheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
EIF3A (eif3s10), Polyclonal Antibody
Full Product Name
EIF3A, CT (EIF3A, EIF3S10, KIAA0139, Eukaryotic translation initiation factor 3 subunit A, Eukaryotic translation initiation factor 3 subunit 10, eIF-3-theta, eIF3 p167, eIF3 p180, eIF3 p185)
Product Gene Name
anti-eif3s10 antibody
Product Synonym Names
Anti -EIF3A, CT (EIF3A, EIF3S10, KIAA0139, Eukaryotic translation initiation factor 3 subunit A, Eukaryotic translation initiation factor 3 subunit 10, eIF-3-theta, eIF3 p167, eIF3 p180, eIF3 p185)
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity/Purification
Affinity Purified
Purified by Protein A affinity chromatography.
Specificity
Human
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
151,292 Da
Chromosome Location
Chromosome: 13; NC_007124.5 (19328847..19362476). Location: chromosome: 13
3D Structure
ModBase 3D Structure for Q6PCR7
Immunogen
EIF3A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1218-1247 amino acids from the C-terminal region of human EIF3A.

Product Categories/Family for anti-eif3s10 antibody

Antibodies; Abs to Translation Initiation Factors
Applications Tested/Suitable for anti-eif3s10 antibody
ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-eif3s10 antibody
Suitable for use in Western Blot, Immunohistochemistry, ELISA
Dilution: ELISA: 1:1,000
Western Blot: 1:100-500
Immunohistochemistry: 1:10-50

Western Blot (WB) of anti-eif3s10 antibody

EIF3A Antibody (C-term) western blot analysis in A2058 cell line lysates (35ug/lane).This demonstrates the EIF3A antibody detected the EIF3A protein (arrow).
Rabbit Anti-eif3s10 Polyclonal Antibody – Cat# MBS6004833

Immunohistochemistry (IHC) of anti-eif3s10 antibody

EIF3A Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human stomach tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of EIF3A Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
Rabbit Anti-eif3s10 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS6004833

Other Notes

Small volumes of anti-eif3s10 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for eif3s10 purchase

MBS6004833 is an antibody targeting eif3s10. Also known as EIF3A, CT (EIF3A, EIF3S10, KIAA0139, Eukaryotic translation initiation factor 3 subunit A, Eukaryotic translation initiation factor 3 subunit 10, eIF-3-theta, eIF3 p167, eIF3 p180, eIF3 p185). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for eif3s10. It may not necessarily be applicable to this product.

NCBI GI #
45433533
NCBI GeneID
327515
NCBI Accession #
NP_956114.2
UniProt Primary Accession #
Q6PCR7
UniProt Secondary Accession #
Q6NYB1
UniProt Related Accession #
Q6PCR7
GenBank Nucleotide #
NM_199820.2
NCBI Official Full Name
eukaryotic translation initiation factor 3 subunit A
NCBI Official Synonym Full Names
eukaryotic translation initiation factor 3, subunit 10 (theta)
NCBI Official Symbol
eif3s10
NCBI Official Synonym Symbols
zgc:66194; zgc:77263; wu:fi15c03
UniProt Protein Name
Eukaryotic translation initiation factor 3 subunit A
UniProt Synonym Protein Names
Eukaryotic translation initiation factor 3 subunit 10; eIF-3-theta
Protein Family
Eukaryotic translation initiation factor
UniProt Gene Name
eif3a
UniProt Synonym Gene Names
eif3s10; eIF3a
UniProt Entry Name
EIF3A_DANRE
NCBI Protein Information
eukaryotic translation initiation factor 3 subunit A; eIF3a; eIF-3-theta; eukaryotic translation initiation factor 3 subunit 10

UniProt Comments for eif3s10

Function: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome

By similarity. HAMAP-Rule MF_03000

Subunit structure: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: eif3a, eif3b, eif3c, eif3d, eif3e, eif3f, eif3g, eif3h, eif3i, eif3j, eif3k, eif3l and eif3m

By similarity.

Subcellular location: Cytoplasm

By similarity HAMAP-Rule MF_03000.

Sequence similarities: Belongs to the eIF-3 subunit A family.Contains 1 PCI domain.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-eif3s10 antibody

 Products by Pathway  Pathway Diagram
 Activation Of The MRNA Upon Binding Of The Cap-binding Complex And EIFs, And Subsequent Binding To 43S Pathway antibodies  Activation Of The MRNA Upon Binding Of The Cap-binding Complex And EIFs, And Subsequent Binding To 43S Pathway Diagram
 Cap-dependent Translation Initiation Pathway antibodies  Cap-dependent Translation Initiation Pathway Diagram
 Eukaryotic Translation Initiation Pathway antibodies  Eukaryotic Translation Initiation Pathway Diagram
 Formation Of A Pool Of Free 40S Subunits Pathway antibodies  Formation Of A Pool Of Free 40S Subunits Pathway Diagram
 Formation Of The Ternary Complex, And Subsequently, The 43S Complex Pathway antibodies  Formation Of The Ternary Complex, And Subsequently, The 43S Complex Pathway Diagram
 GTP Hydrolysis And Joining Of The 60S Ribosomal Subunit Pathway antibodies  GTP Hydrolysis And Joining Of The 60S Ribosomal Subunit Pathway Diagram
 Gene Expression Pathway antibodies  Gene Expression Pathway Diagram
 L13a-mediated Translational Silencing Of Ceruloplasmin Expression Pathway antibodies  L13a-mediated Translational Silencing Of Ceruloplasmin Expression Pathway Diagram
 Metabolism Of Proteins Pathway antibodies  Metabolism Of Proteins Pathway Diagram
 RNA Transport Pathway antibodies  RNA Transport Pathway Diagram

Diseases associated with anti-eif3s10 antibody

 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >4 publications with eif3s10 and Neoplasms
 Death Antibodies  >2 publications with eif3s10 and Death
 Immune System Diseases Antibodies  >1 publications with eif3s10 and Immune System Diseases
 Kidney Diseases Antibodies  >1 publications with eif3s10 and Kidney Diseases

Organs/Tissues associated with anti-eif3s10 antibody

 Organ/Tissue Name  Pubmed Publications
 Kidney Antibodies  >2 publications with eif3s10 and Kidney
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