Rabbit Anti-EIF3K Polyclonal Antibody – Cat# MBS6295039

EIF3K Antibody (C-term) western blot analysis in T47D cell line lysates (35ug/lane).This demonstrates the EIF3K antibody detected the EIF3K protein (arrow).

EIF3K Antibody – Rabbit Polyclonal

Name: EIF3K Antibody; Polyclonal; Rabbit; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS6295039
Price: 1060 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6295039

The 700-kD eukaryotic translation initiation factor-3 (eIF3) is the largest eIF and contains at least 12 subunits, including EIF2S12. eIF3 plays an essential role in translation by binding directly to the 40S ribosomal subunit and promoting formation of the… More details

$1060 / 0.2 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

EIF3K, Polyclonal Antibody

Full Product Name

EIF3K, CT (EIF3K, EIF3S12, Eukaryotic translation initiation factor 3 subunit K, Eukaryotic translation initiation factor 3 subunit 12, Muscle-specific gene M9 protein, PLAC-24, eIF-3 p25, eIF-3 p28) (AP)

Product Gene Name

anti-EIF3K antibody

Product Synonym Names

EIF3K; EIF3S12; Eukaryotic translation initiation factor 3 subunit K; Eukaryotic translation initiation factor 3 subunit 12; Muscle-specific gene M9 protein; PLAC-24; eIF-3 p25; eIF-3 p28

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human

Form/Format

Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Alkaline Phosphatase (AP).

Purity/Purification

Purified by Protein A Affinity Chromatography.

Preparation and Storage

Store product at 4 degree C. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Molecular Weight

25,060 Da

Chromosome Location

Chromosome: 19; NC_000019.9 (39109722..39127595). Location: 19q13.2

OMIM

609596

3D Structure

ModBase 3D Structure for Q9UBQ5

Immunogen

EIF3K antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 175-204 amino acids from the C-terminal region of human EIF3K.

Conjugate

Note

Preservative Free

Product Categories/Family for anti-EIF3K antibody

Antibodies; Translation Initiation Factors

Applications Tested/Suitable for anti-EIF3K antibody

Western Blot (WB), ELISA (EIA)

Application Notes for anti-EIF3K antibody

WB: 1:100-500
ELISA: 1:1,000
Applications are based on unconjugated antibody.

Product References and Citations for anti-EIF3K antibody

Zhou, M., et al. Proc. Natl. Acad. Sci. U.S.A. 105(47):18139-18144(2008). Lin, Y.M., et al. J. Cell. Sci. 121 (PT 14), 2382-2393 (2008): Masutani, M., et al. EMBO J. 26(14):3373-3383(2007). Damoc, E., et al. Mol. Cell Proteomics 6(7):1135-1146(2007). Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007).

Other Notes

Small volumes of anti-EIF3K antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for EIF3K purchase

MBS6295039 is an antibody targeting EIF3K. Also known as EIF3K, CT (EIF3K, EIF3S12, Eukaryotic translation initiation factor 3 subunit K, Eukaryotic translation initiation factor 3 subunit 12, Muscle-specific gene M9 protein, PLAC-24, eIF-3 p25, eIF-3 p28) (AP). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for EIF3K. It may not necessarily be applicable to this product.

NCBI GI #

10801345

NCBI GeneID

27335

NCBI Accession #

NP_037366.1

UniProt Primary Accession #

Q9UBQ5

UniProt Secondary Accession #

Q96IQ0; Q9Y6D1; A8K0I9

UniProt Related Accession #

Q9UBQ5

GenBank Nucleotide #

NM_013234.2

NCBI Official Full Name

eukaryotic translation initiation factor 3 subunit K

NCBI Official Synonym Full Names

eukaryotic translation initiation factor 3, subunit K

NCBI Official Symbol

EIF3K

NCBI Official Synonym Symbols

M9; ARG134; PLAC24; PTD001; EIF3S12; HSPC029; MSTP001; PLAC-24; PRO1474; EIF3-p28

UniProt Protein Name

Eukaryotic translation initiation factor 3 subunit K

UniProt Synonym Protein Names

Eukaryotic translation initiation factor 3 subunit 12; Muscle-specific gene M9 protein; PLAC-24; eIF-3 p25; eIF-3 p28

Protein Family

Eukaryotic translation initiation factor

UniProt Gene Name

EIF3K

UniProt Synonym Gene Names

EIF3S12; eIF3k

UniProt Entry Name

EIF3K_HUMAN

NCBI Protein Information

eukaryotic translation initiation factor 3 subunit K; eIF-3 p25; eIF-3 p28; muscle specific; muscle-specific gene M9 protein; eukaryotic translation initiation factor 3 subunit 12; eukaryotic translation initiation factor 3, subunit 12

UniProt Comments for EIF3K

EIF3K: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. Belongs to the eIF-3 subunit K family.

Protein type: Translation initiation; Translation

Chromosomal Location of Human Ortholog: 19q13.2

Cellular Component: eukaryotic translation initiation factor 3 complex; membrane; cytoplasm; cytosol; nucleus

Molecular Function: protein binding; translation initiation factor activity; ribosome binding

Biological Process: cellular protein metabolic process; translation; translational initiation; gene expression; formation of translation preinitiation complex; regulation of translational initiation

Research Articles on EIF3K

1. eIF3k, originally identified as the smallest subunit of eukaryotic translation initiation factor 3 (eIF3) complexes, also localizes to keratin intermediate filaments and physically associates with K18 in epithelial cells.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-EIF3K antibody

Reference Product	PubMed Publications
EIF3J antibody	>1 publications with EIF3K and EIF3J
EIF3G antibody	>1 publications with EIF3K and EIF3G
EIF3C antibody	>1 publications with EIF3K and EIF3C
CCND3 antibody	>1 publications with EIF3K and CCND3

Pathways associated with anti-EIF3K antibody

Products by Pathway	Pathway Diagram
Activation Of The MRNA Upon Binding Of The Cap-binding Complex And EIFs, And Subsequent Binding To 43S Pathway antibodies	Activation Of The MRNA Upon Binding Of The Cap-binding Complex And EIFs, And Subsequent Binding To 43S Pathway Diagram
Cap-dependent Translation Initiation Pathway antibodies	Cap-dependent Translation Initiation Pathway Diagram
Eukaryotic Translation Initiation Pathway antibodies	Eukaryotic Translation Initiation Pathway Diagram
Formation Of A Pool Of Free 40S Subunits Pathway antibodies	Formation Of A Pool Of Free 40S Subunits Pathway Diagram
Formation Of The Ternary Complex, And Subsequently, The 43S Complex Pathway antibodies	Formation Of The Ternary Complex, And Subsequently, The 43S Complex Pathway Diagram
GTP Hydrolysis And Joining Of The 60S Ribosomal Subunit Pathway antibodies	GTP Hydrolysis And Joining Of The 60S Ribosomal Subunit Pathway Diagram
Gene Expression Pathway antibodies	Gene Expression Pathway Diagram
L13a-mediated Translational Silencing Of Ceruloplasmin Expression Pathway antibodies	L13a-mediated Translational Silencing Of Ceruloplasmin Expression Pathway Diagram
Metabolism Of Proteins Pathway antibodies	Metabolism Of Proteins Pathway Diagram
Ribosomal Scanning And Start Codon Recognition Pathway antibodies	Ribosomal Scanning And Start Codon Recognition Pathway Diagram

Diseases associated with anti-EIF3K antibody

Disease Name	Pubmed Publications
Neoplasms Antibodies	>1 publications with EIF3K and Neoplasms

Organs/Tissues associated with anti-EIF3K antibody

Organ/Tissue Name	Pubmed Publications
Liver Antibodies	>3 publications with EIF3K and Liver
Brain Antibodies	>3 publications with EIF3K and Brain
Adipose Tissue Antibodies	>2 publications with EIF3K and Adipose Tissue
Muscle Antibodies	>2 publications with EIF3K and Muscle
Mammary Gland Antibodies	>2 publications with EIF3K and Mammary Gland
Connective Tissue Antibodies	>1 publications with EIF3K and Connective Tissue
Blood Antibodies	>1 publications with EIF3K and Blood