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ELOVL2 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6295366

ELOVL2 could be implicated in tissue-specific synthesis of very long chain fatty acids and sphingolipids. This protein may catalyze one or both of the reduction reaction in fatty acid elongation, i.e., conversion of beta-ketoacyl CoA to beta-hydroxyacyl CoA… More details

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Testing Data View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
ELOVL2, Polyclonal Antibody
Full Product Name
ELOVL2, NT (ELOVL2, SSC2, Elongation of very long chain fatty acids protein 2, 3-keto acyl-CoA synthase ELOVL2, ELOVL fatty acid elongase 2) (MaxLight 650)
Product Gene Name
anti-ELOVL2 antibody
Product Synonym Names
ELOVL2; SSC2; Elongation of very long chain fatty acids protein 2; 3-keto acyl-CoA synthase ELOVL2; ELOVL fatty acid elongase 2
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight650.
Purity/Purification
Purified by Protein A Affinity Chromatography.
Preparation and Storage
Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: MaxLight650 conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molecular Weight
34,585 Da
Chromosome Location
Chromosome: 6; NC_000006.11 (10980992..11044624, complement). Location: 6p24.2
OMIM
611814
3D Structure
ModBase 3D Structure for Q9NXB9
Immunogen
ELOVL2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 7~36 amino acids from the N-terminal region of human ELOVL2.
Conjugate
MaxLight650
Note
Preservative Free

Product Categories/Family for anti-ELOVL2 antibody

Antibodies; Enzymes; Synthase
Applications Tested/Suitable for anti-ELOVL2 antibody
Flow Cytometry (FC/FACS), FLISA, Immunohistochemistry (IHC), Western Blot (WB)
Application Notes for anti-ELOVL2 antibody
FC/FACS: 1:10-50
FLISA: 1:1,000
IHC: 1:50-100
WB: 1:100-500
Applications are based on unconjugated antibody.

Product References and Citations for anti-ELOVL2 antibody

Illig, T., et.al., Nat. Genet. 42 (2), 137-141 (2010). Tanaka, T., et.al., PLoS Genet. 5 (1), E1000338 (2009).

Other Notes

Small volumes of anti-ELOVL2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for ELOVL2 purchase

MBS6295366 is an antibody targeting ELOVL2. Also known as ELOVL2, NT (ELOVL2, SSC2, Elongation of very long chain fatty acids protein 2, 3-keto acyl-CoA synthase ELOVL2, ELOVL fatty acid elongase 2) (MaxLight 650). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for ELOVL2. It may not necessarily be applicable to this product.

NCBI GI #
157388945
NCBI GeneID
54898
NCBI Accession #
NP_060240.3
UniProt Primary Accession #
Q9NXB9
UniProt Secondary Accession #
Q6P9E1; Q86W94
UniProt Related Accession #
Q9NXB9
GenBank Nucleotide #
NM_017770.3
NCBI Official Full Name
elongation of very long chain fatty acids protein 2
NCBI Official Synonym Full Names
ELOVL fatty acid elongase 2
NCBI Official Symbol
ELOVL2
NCBI Official Synonym Symbols
SSC2
UniProt Protein Name
Elongation of very long chain fatty acids protein 2
UniProt Synonym Protein Names
3-keto acyl-CoA synthase ELOVL2; ELOVL fatty acid elongase 2; ELOVL FA elongase 2; Very-long-chain 3-oxoacyl-CoA synthase 2
Protein Family
Elongation of very long chain fatty acids protein
UniProt Gene Name
ELOVL2
UniProt Synonym Gene Names
SSC2; ELOVL FA elongase 2
UniProt Entry Name
ELOV2_HUMAN
NCBI Protein Information
elongation of very long chain fatty acids protein 2; ELOVL FA elongase 2; 3-keto acyl-CoA synthase ELOVL2; very-long-chain 3-oxoacyl-CoA synthase 2; elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 2

UniProt Comments for ELOVL2

ELOVL2: Condensing enzyme that catalyzes the synthesis of polyunsaturated very long chain fatty acid (C20- and C22-PUFA). Acts specifically toward polyunsaturated acyl-CoA with the higher activity toward C20:4(n-6) acyl-CoA. Belongs to the ELO family.

Protein type: Membrane protein, multi-pass; Lipid Metabolism - unsaturated fatty acid biosynthesis; EC 2.3.1.199; Membrane protein, integral

Chromosomal Location of Human Ortholog: 6p24.2

Cellular Component: endoplasmic reticulum membrane; endoplasmic reticulum; integral to membrane

Molecular Function: protein binding; fatty acid elongase activity

Biological Process: unsaturated fatty acid metabolic process; very-long-chain fatty acid biosynthetic process; linoleic acid metabolic process; triacylglycerol biosynthetic process; unsaturated fatty acid biosynthetic process; cellular lipid metabolic process
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Research Articles on ELOVL2

1. we do not found the association between rs3756593 of ELOVL2 gene and acute coronary syndrome in Chinese Han population

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-ELOVL2 antibody

 Reference Product  PubMed Publications
 ELOVL5 antibody  >17 publications with ELOVL2 and ELOVL5
 FADS1 antibody  >17 publications with ELOVL2 and FADS1
 FADS2 antibody  >16 publications with ELOVL2 and FADS2
 SCD antibody  >2 publications with ELOVL2 and SCD
 FABP4 antibody  >1 publications with ELOVL2 and FABP4
 FADS3 antibody  >1 publications with ELOVL2 and FADS3
 DGAT2 antibody  >1 publications with ELOVL2 and DGAT2

Pathways associated with anti-ELOVL2 antibody

 Products by Pathway  Pathway Diagram
 Biosynthesis Of Unsaturated Fatty Acids Pathway antibodies  Biosynthesis Of Unsaturated Fatty Acids Pathway Diagram
 Biosynthesis Of Unsaturated Fatty Acids Pathway antibodies  Biosynthesis Of Unsaturated Fatty Acids Pathway Diagram
 Fatty Acyl-CoA Biosynthesis Pathway antibodies  Fatty Acyl-CoA Biosynthesis Pathway Diagram
 Fatty Acid Biosynthesis, Elongation, Endoplasmic Reticulum Pathway antibodies  Fatty Acid Biosynthesis, Elongation, Endoplasmic Reticulum Pathway Diagram
 Fatty Acid Biosynthesis, Elongation, Endoplasmic Reticulum Pathway antibodies  Fatty Acid Biosynthesis, Elongation, Endoplasmic Reticulum Pathway Diagram
 Fatty Acid Elongation Pathway antibodies  Fatty Acid Elongation Pathway Diagram
 Fatty Acid Elongation Pathway antibodies  Fatty Acid Elongation Pathway Diagram
 Fatty Acid, Triacylglycerol, And Ketone Body Metabolism Pathway antibodies  Fatty Acid, Triacylglycerol, And Ketone Body Metabolism Pathway Diagram
 Linoleic Acid (LA) Metabolism Pathway antibodies  Linoleic Acid (LA) Metabolism Pathway Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram

Diseases associated with anti-ELOVL2 antibody

 Disease Name  Pubmed Publications
 Fatty Liver Antibodies  >12 publications with ELOVL2 and Fatty Liver
 Inflammation Antibodies  >5 publications with ELOVL2 and Inflammation
 Liver Diseases Antibodies  >2 publications with ELOVL2 and Liver Diseases
 Myocardial Infarction Antibodies  >1 publications with ELOVL2 and Myocardial Infarction
 Weight Gain Antibodies  >1 publications with ELOVL2 and Weight Gain
 Carcinoma, Hepatocellular Antibodies  >1 publications with ELOVL2 and Carcinoma, Hepatocellular
 Cognition Disorders Antibodies  >1 publications with ELOVL2 and Cognition Disorders
 Weight Loss Antibodies  >1 publications with ELOVL2 and Weight Loss
 Disease Models, Animal Antibodies  >1 publications with ELOVL2 and Disease Models, Animal
 Pain Antibodies  >1 publications with ELOVL2 and Pain

Organs/Tissues associated with anti-ELOVL2 antibody

 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >15 publications with ELOVL2 and Liver
 Eye Antibodies  >4 publications with ELOVL2 and Eye
 Muscle Antibodies  >4 publications with ELOVL2 and Muscle
 Brain Antibodies  >4 publications with ELOVL2 and Brain
 Embryonic Tissue Antibodies  >2 publications with ELOVL2 and Embryonic Tissue
 Testis Antibodies  >2 publications with ELOVL2 and Testis
 Nerve Antibodies  >1 publications with ELOVL2 and Nerve
 Kidney Antibodies  >1 publications with ELOVL2 and Kidney
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