Rabbit Anti-ENOSF1 Polyclonal Antibody – Cat# MBS9209488

ENOSF1 Antibody (N-term) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the ENOSF1 antibody detected the ENOSF1 protein (arrow).

ENOSF1 Antibody – Rabbit Polyclonal

Name: ENOSF1 Antibody; Polyclonal; Rabbit; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS9209488
Price: 240 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS9209488

ENOSF1 was originally identified as a naturallyoccurring antisense transcript to the human thymidylate synthasegene. Alternate splice variants have been described, one of which(named rTSalpha) represents an alternate 3'UTR that iscomplementary to the 3'UTR… More details

$240 / 0.08 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

ENOSF1, Polyclonal Antibody

Full Product Name

ENOSF1 Antibody (N-term)

Product Gene Name

anti-ENOSF1 antibody

Product Synonym Names

Mitochondrial enolase superfamily member 1; Antisense RNA to thymidylate synthase; rTS; L-fuconate dehydratase; ENOSF1; RTS; TYMSAS

Clonality

Polyclonal

Isotype

Rabbit Ig

Host

Rabbit

Species Reactivity

Human

Form/Format

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Purity/Purification

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Concentration

Vial Concentration: 0.5 (lot specific)

Specificity

This ENOSF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 63-92 amino acids from the N-terminal region of human ENOSF1.

Preparation and Storage

Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.

Antibody/Peptide Pairs

ENOSF1 peptide (MBS9221703) is used for blocking the activity of ENOSF1 antibody (MBS9209488)

Molecular Weight

49786

Immunogen Sequence Positions

63-92

OMIM

607427

3D Structure

ModBase 3D Structure for Q7L5Y1

Antigen Type

Synthetic Peptide

Antigen Source

HUMAN

Product Categories/Family for anti-ENOSF1 antibody

Cell Biology; Metabolism; Signal transduction

Applications Tested/Suitable for anti-ENOSF1 antibody

Western Blot (WB), ELISA (EIA)

Application Notes for anti-ENOSF1 antibody

WB~~1:1000

Product References and Citations for anti-ENOSF1 antibody

Giusti, B., et al. Thromb. Haemost. 104(2):231-242(2010)
Wang, Y., et al. J. Hum. Genet. 55(8):490-494(2010)
Cross, D.S., et al. BMC Genet. 11, 51 (2010) :
Giusti, B., et al. J. Med. Genet. 45(11):721-730(2008)
Giusti, B., et al. Biochem. Genet. 46 (7-8), 406-423 (2008) :

Other Notes

Small volumes of anti-ENOSF1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for ENOSF1 purchase

MBS9209488 is an antibody targeting ENOSF1. Also known as ENOSF1 Antibody (N-term). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for ENOSF1. It may not necessarily be applicable to this product.

NCBI GI #

186972148

NCBI GeneID

55556

NCBI Accession #

NP_001119595.1

NCBI Related Accession #

NP_059982.2; NP_974487.1

UniProt Primary Accession #

Q7L5Y1

UniProt Secondary Accession #

Q15407; Q15594; Q15595; Q6ZS08; Q9HAS5; Q9HAS6; A6NMP3; A8K9R5; B3KSL6; B3KXE4; D3DUH0

UniProt Related Accession #

Q7L5Y1

GenBank Nucleotide #

NM_001126123.3

NCBI Official Full Name

mitochondrial enolase superfamily member 1 isoform rTSalpha

NCBI Official Synonym Full Names

enolase superfamily member 1

NCBI Official Symbol

ENOSF1

NCBI Official Synonym Symbols

RTS; TYMSAS; HSRTSBETA

UniProt Protein Name

Mitochondrial enolase superfamily member 1

UniProt Synonym Protein Names

Antisense RNA to thymidylate synthase; rTS; L-fuconate dehydratase

Protein Family

Mitochondrial enolase superfamily

UniProt Gene Name

ENOSF1

UniProt Synonym Gene Names

RTS; TYMSAS; rTS

UniProt Entry Name

ENOF1_HUMAN

NCBI Protein Information

mitochondrial enolase superfamily member 1

NCBI Summary for ENOSF1

This gene was originally identified as a naturally occurring antisense transcript to the human thymidylate synthase gene. Alternate splice variants have been described, one of which (named rTSalpha) represents an alternate 3'UTR that is complementary to the 3'UTR and terminal intron of the thymidylate synthase (TS) RNA and down-regulates TS expression. Other transcript variants (rTSbeta and rTSgamma) do not overlap the TS locus. The function of this gene appears to be primarily to regulate expression of the TS locus both via the antisense transcript as well as through the encoded proteins. [provided by RefSeq, Mar 2010]

UniProt Comments for ENOSF1

ENOSF1: May regulate thymidylate synthase activity. Belongs to the mandelate racemase/muconate lactonizing enzyme family. ENOSF1 subfamily. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 4.2.1.68; Isomerase; Mitochondrial

Chromosomal Location of Human Ortholog: 18p11.32

Cellular Component: mitochondrion

Molecular Function: magnesium ion binding; L-fuconate dehydratase activity; isomerase activity

Biological Process: cellular carbohydrate catabolic process; amino acid catabolic process

Research Articles on ENOSF1

1. The toxicity polymorphism in the TYMS region may actually act through ENOSF1

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-ENOSF1 antibody

Reference Product	PubMed Publications
TYMS antibody	>9 publications with ENOSF1 and TYMS
BHMT2 antibody	>3 publications with ENOSF1 and BHMT2
MAN2B2 antibody	>1 publications with ENOSF1 and MAN2B2
ENPP2 antibody	>1 publications with ENOSF1 and ENPP2

Pathways associated with anti-ENOSF1 antibody

Products by Pathway	Pathway Diagram
Glutathione Metabolism Pathway antibodies	Glutathione Metabolism Pathway Diagram
Glutathione Metabolism Pathway antibodies	Glutathione Metabolism Pathway Diagram

Diseases associated with anti-ENOSF1 antibody

Disease Name	Pubmed Publications
Hypertension Antibodies	>1 publications with ENOSF1 and Hypertension
Pancreatic Neoplasms Antibodies	>1 publications with ENOSF1 and Pancreatic Neoplasms