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ENPP6 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS7001845

Choline-specific glycerophosphodiester phosphodiesterase. The preferred substrate may be lysosphingomyelin. Hydrolyzes lysophosphatidylcholine (LPC) to form monoacylglycerol and phosphorylcholine but not lysophosphatidic acid, showing it has a… More details

$230 / 0.05 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
ENPP6, Polyclonal Antibody
Full Product Name
ENPP6 Antibody
Product Gene Name
anti-ENPP6 antibody
Product Synonym Names
Ectonucleotide pyrophosphatase/phosphodiesterase family member 6; E-NPP 6; NPP-6; Choline-specific glycerophosphodiester phosphodiesterase; Glycerophosphocholine cholinephosphodiesterase; GPC-Cpde; ENPP6; UNQ1889/PRO4334
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Liquid
Purity/Purification
>95%,Protein G purified
Preparation and Storage
Shipped at 4 degree C. Upon delivery, aliquot and store at -20 degree C or -80 degree C.
Matching Pairs
Unconjugated Antibody: ENPP6 (MBS7001845)
Biotin Conjugated Antibody: ENPP6 (MBS7003983)
Matching Pairs
Unconjugated Antibody: ENPP6 (MBS7001845)
HRP Conjugated Antibody: ENPP6 (MBS7005046)
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Molecular Weight
50,241 Da
3D Structure
ModBase 3D Structure for Q6UWR7
Immunogen
Recombinant human Ectonucleotide pyrophosphatase/phosphodiesterase family member 6 protein
Conjugation
Non-conjugated
Storage Buffer
Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-161955
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-ENPP6 antibody
ELISA (EIA), Immunohistochemistry (IHC)

Immunohistochemistry (IHC) of anti-ENPP6 antibody

Immunohistochemistry of paraffin-embedded human kidney tissue using MBS7001845 at dilution of 1:100
Rabbit Anti-ENPP6 Polyclonal Antibody – Cat# MBS7001845

Immunohistochemistry (IHC) of anti-ENPP6 antibody

Immunohistochemistry of paraffin-embedded human brain tissue using MBS7001845 at dilution of 1:100
Rabbit Anti-ENPP6 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS7001845

Immunohistochemistry (IHC) of anti-ENPP6 antibody

Immunofluorescent analysis of MCF-7 cells using MBS7001845 at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
Rabbit Anti-ENPP6 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS7001845

Other Notes

Small volumes of anti-ENPP6 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for ENPP6 purchase

MBS7001845 is an antibody targeting ENPP6. Also known as ENPP6 Antibody. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for ENPP6. It may not necessarily be applicable to this product.

NCBI GI #
23503267
NCBI GeneID
133121
NCBI Accession #
NP_699174.1
UniProt Primary Accession #
Q6UWR7
UniProt Secondary Accession #
Q4W5Q1; Q96M57
UniProt Related Accession #
Q6UWR7
GenBank Nucleotide #
NM_153343.3
NCBI Official Full Name
ectonucleotide pyrophosphatase/phosphodiesterase family member 6
NCBI Official Synonym Full Names
ectonucleotide pyrophosphatase/phosphodiesterase 6
NCBI Official Symbol
ENPP6
NCBI Official Synonym Symbols
NPP6
UniProt Protein Name
Ectonucleotide pyrophosphatase/phosphodiesterase family member 6
UniProt Synonym Protein Names
Choline-specific glycerophosphodiester phosphodiesterase; Glycerophosphocholine cholinephosphodiesterase; GPC-Cpde
Protein Family
Ectonucleotide pyrophosphatase/phosphodiesterase family
UniProt Gene Name
ENPP6
UniProt Synonym Gene Names
E-NPP 6; NPP-6; GPC-Cpde
UniProt Entry Name
ENPP6_HUMAN
NCBI Protein Information
ectonucleotide pyrophosphatase/phosphodiesterase family member 6

UniProt Comments for ENPP6

ENPP6: Choline-specific glycerophosphodiester phosphodiesterase. Hydrolyzes lysophosphatidylcholine (LPC) to form monoacylglycerol and phosphorylcholine but not lysophosphatidic acid, showing it has a lysophospholipase C activity. Has a preference for LPC with short (12:0 and 14:0) or polyunsaturated (18:2 and 20:4) fatty acids. Also hydrolyzes glycerophosphorylcholine and sphingosylphosphorylcholine efficiently. Hydrolyzes the classical substrate for phospholipase C, p-nitrophenyl phosphorylcholine in vitro, while it does not hydrolyze the classical nucleotide phosphodiesterase substrate, p- nitrophenyl thymidine 5'-monophosphate. Does not hydrolyze diacyl phospholipids such as phosphatidylethanolamine, phosphatidylinositol, phosphatidylserine, phosphatidylglycerol and phosphatidic acid. Belongs to the nucleotide pyrophosphatase/phosphodiesterase family.

Protein type: Membrane protein, GPI anchor; Motility/polarity/chemotaxis; Membrane protein, integral; Phosphodiesterase; EC 3.1.4.38; Lipid Metabolism - ether lipid

Chromosomal Location of Human Ortholog: 4q35.1

Cellular Component: extracellular region; plasma membrane

Molecular Function: glycerophosphocholine cholinephosphodiesterase activity; glycerophosphodiester phosphodiesterase activity; phosphoric diester hydrolase activity

Biological Process: choline metabolic process; lipid catabolic process; lipid metabolic process
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Research Articles on ENPP6

1. NPP6 has a specific role through the hydrolysis of polyunsaturated LPC, glycerophosphorylcholine, or sphingosylphosphorylcholine in kidney and brain

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-ENPP6 antibody

 Reference Product  PubMed Publications
 PLA2G4E antibody  >1 publications with ENPP6 and PLA2G4E
 ENPP2 antibody  >1 publications with ENPP6 and ENPP2

Pathways associated with anti-ENPP6 antibody

 Products by Pathway  Pathway Diagram
 Ether Lipid Metabolism Pathway antibodies  Ether Lipid Metabolism Pathway Diagram
 Ether Lipid Metabolism Pathway antibodies  Ether Lipid Metabolism Pathway Diagram

Diseases associated with anti-ENPP6 antibody

 Disease Name  Pubmed Publications
 Obesity Antibodies  >1 publications with ENPP6 and Obesity
 Breast Neoplasms Antibodies  >1 publications with ENPP6 and Breast Neoplasms
 Fatty Liver Antibodies  >1 publications with ENPP6 and Fatty Liver
 Weight Loss Antibodies  >1 publications with ENPP6 and Weight Loss

Organs/Tissues associated with anti-ENPP6 antibody

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >4 publications with ENPP6 and Brain
 Kidney Antibodies  >3 publications with ENPP6 and Kidney
 Nerve Antibodies  >2 publications with ENPP6 and Nerve
 Heart Antibodies  >1 publications with ENPP6 and Heart
 Uncharacterized Tissue Antibodies  >1 publications with ENPP6 and Uncharacterized Tissue
 Embryonic Tissue Antibodies  >1 publications with ENPP6 and Embryonic Tissue
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