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ETV3 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3222810

Transcriptional repressor that contribute to growth arrest during terminal macrophage differentiation by repressing target genes involved in Ras-dependent proliferation. Represses MMP1 promoter activity. More details

$490 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
ETV3, Polyclonal Antibody
Full Product Name
ETV3 Antibody - C-terminal region
Product Gene Name
Product Synonym Gene Name
PE1; METS; PE-1; bA110J1.4
Immunogen Sequence
Synthetic peptide located within the following region: TPSGEPLEVT EDSEDRPGKE PSAPEKKEDA LMPPKLRLKR RWNDDPEARE
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human
Form/Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Purity/Purification
Affinity purified
Preparation and Storage
For short term use, store at 2-8 degree C up to 1 week. For long term storage, store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Antibody/Peptide Pairs
ETV3 peptide (MBS3247477) is used for blocking the activity of ETV3 antibody (MBS3222810)
Molecular Weight
56 kDa
OMIM
164873
3D Structure
ModBase 3D Structure for P41162
Immunogen
The immunogen is a synthetic peptide directed towards the C terminal region of human ETV3
Applications Tested/Suitable for anti-ETV3 antibody
Western Blot (WB)

Western Blot (WB) of anti-ETV3 antibody

Host: Rabbit
Target Name: ETV3
Sample Tissue: Human 786-0 Whole Cell lysates
Antibody Dilution: 1ug/ml
Rabbit Anti-ETV3 Polyclonal Antibody – Cat# MBS3222810

Other Notes

Small volumes of anti-ETV3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for ETV3 purchase

MBS3222810 is an antibody targeting ETV3. Also known as ETV3 Antibody - C-terminal region. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for ETV3. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
ETS translocation variant 3 isoform 1
NCBI Official Synonym Full Names
ETS variant 3
NCBI Official Symbol
ETV3
NCBI Official Synonym Symbols
PE1; METS; PE-1
UniProt Protein Name
ETS translocation variant 3
UniProt Synonym Protein Names
ETS domain transcriptional repressor PE1; PE-1; Mitogenic Ets transcriptional suppressor
Protein Family
UniProt Gene Name
ETV3
UniProt Synonym Gene Names
METS; PE1; PE-1
UniProt Entry Name
ETV3_HUMAN
NCBI Protein Information
ETS translocation variant 3

UniProt Comments for ETV3

ETV3: Transcriptional repressor that contribute to growth arrest during terminal macrophage differentiation by repressing target genes involved in Ras-dependent proliferation. Represses MMP1 promoter activity. Belongs to the ETS family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: DNA-binding

Chromosomal Location of Human Ortholog: 1q21-q23

Cellular Component: transcriptional repressor complex; nucleus

Molecular Function: sequence-specific DNA binding

Biological Process: regulation of transcription from RNA polymerase II promoter; transcription from RNA polymerase II promoter; negative regulation of transcription from RNA polymerase II promoter; cell differentiation
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-ETV3 antibody

 Reference Product  PubMed Publications
 DDX20 antibody  >1 publications with ETV3 and DDX20

Diseases associated with anti-ETV3 antibody

 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >3 publications with ETV3 and Neoplasms

Organs/Tissues associated with anti-ETV3 antibody

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