• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

FGD3 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6012849

Promotes the formation of filopodia. May activate CDC42, a member of the Ras-like family of Rho- and Rac proteins, by exchanging bound GDP for free GTP. Plays a role in regulating the actin cytoskeleton and cell shape. More details

$970 / 0.1 mg +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
FGD3, Polyclonal Antibody
Full Product Name
FGD3 (ZFYVE5, FYVE, RhoGEF and PH Domain-containing Protein 3, Zinc Finger FYVE Domain-containing Protein 5, FLJ00004, MGC117260)
Product Gene Name
anti-FGD3 antibody
Product Synonym Names
Anti -FGD3 (ZFYVE5, FYVE, RhoGEF and PH Domain-containing Protein 3, Zinc Finger FYVE Domain-containing Protein 5, FLJ00004, MGC117260)
Immunogen Sequence
MESGRGSSTP PGPIAALGMP DTGPGSSSLG KLQALPVGPR AHCGDPVSLA AAGDGSPDIG PTGELSGSLK IPNRDSGIDS PSSSVAGENF PCEEGLEAGP SPTVLGAHAE MALDSQVPKV TPQEEADSDV GEEPDSENTP QKADKDAGLA QHSGPQKLLH IAQELLHTEE TYVKRLHLLD QVFCTRLTDA GIPPEVIMGI FSNISSIHRF HGQFLLPELK TRITEEWDTN PRLGDILQKL APFLKMYGEY VKNFDRAVGL VSTWTQRSPL FKDVIHSIQK QEVCGNLTLQ HHMLEPVQRV PRYELLLKDY LKRLPQDAPD RKDAERSLEL ISTAANHSNA AIRKVEKMHK LLEVYEQLGG EEDIVNPANE LIKEGQIQKL SAKNGTPQDR HLFLFNSMIL YCVPKLRLMG QKFSVREKMD ISGLQVQDIV KPNTAHTFII TGRKRSLELQ TRTEEEKKEW IQIIQATIEK HKQNSETFKA FGGAFSQDED PSLSPDMPIT STSPVEPVVT TEGSSGAAGL EPRKLSSKTR RDKEKQSCKS CGETFNSITK RRHHCKLCGA VICGKCSEFK AENSRQSRVC RDCFLTQPVA PESTEKTPTA DPQPSLLCGP LRLSESGETW SEVWAAIPMS DPQVLHLQGG SQDGRLPRTI PLPSCKLSVP DPEERLDSGH VWKLQWAKQS WYLSASSAEL QQQWLETLST AAHGDTAQDS PGALQLQVPM GAAAP
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2.
Purity/Purification
Affinity Purified
Purified by Protein A affinity chromatography.
Specificity
Recognizes human FGD3.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
79,401 Da
Chromosome Location
Chromosome: 9; NC_000009.11 (95709601..95798518). Location: chromosome: 9
3D Structure
ModBase 3D Structure for Q5JSP0
Immunogen
Full length human FGD3, aa1-725 (AAH32429.1).

Product Categories/Family for anti-FGD3 antibody

Antibodies; Abs to G Proteins
Applications Tested/Suitable for anti-FGD3 antibody
Western Blot (WB)
Application Notes for anti-FGD3 antibody
Suitable for use in Western Blot.

Western Blot (WB) of anti-FGD3 antibody

Western Blot analysis of FGD3 expression in transfected 293T cell line by FGD3 polyclonal antibody. Lane 1: FGD3 transfected lysate (79.4kD). Lane 2: Non-transfected lysate.
Rabbit Anti-FGD3 Polyclonal Antibody – Cat# MBS6012849

Other Notes

Small volumes of anti-FGD3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for FGD3 purchase

MBS6012849 is an antibody targeting FGD3. Also known as FGD3 (ZFYVE5, FYVE, RhoGEF and PH Domain-containing Protein 3, Zinc Finger FYVE Domain-containing Protein 5, FLJ00004, MGC117260). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for FGD3. It may not necessarily be applicable to this product.

NCBI GI #
31322344
NCBI GeneID
89846
NCBI Accession #
AAP20645.1
UniProt Primary Accession #
Q5JSP0
UniProt Secondary Accession #
Q4VX84; Q7Z7D9; Q8N5G1
UniProt Related Accession #
Q5JSP0
NCBI Official Full Name
FGD3
NCBI Official Synonym Full Names
FYVE, RhoGEF and PH domain containing 3
NCBI Official Symbol
FGD3
NCBI Official Synonym Symbols
ZFYVE5
UniProt Protein Name
FYVE, RhoGEF and PH domain-containing protein 3
UniProt Synonym Protein Names
Zinc finger FYVE domain-containing protein 5
Protein Family
FYVE, RhoGEF and PH domain-containing protein
UniProt Gene Name
FGD3
UniProt Synonym Gene Names
ZFYVE5
UniProt Entry Name
FGD3_HUMAN
NCBI Protein Information
FYVE, RhoGEF and PH domain-containing protein 3; FGD1 family, member 3; faciogenital dysplasia 3; zinc finger FYVE domain-containing protein 5

UniProt Comments for FGD3

FGD3: Promotes the formation of filopodia. May activate CDC42, a member of the Ras-like family of Rho- and Rac proteins, by exchanging bound GDP for free GTP. Plays a role in regulating the actin cytoskeleton and cell shape. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: GEFs, Rac/Rho; GEFs

Chromosomal Location of Human Ortholog: -

Cellular Component: ruffle; Golgi apparatus; cytoskeleton; lamellipodium; cytoplasm; cytosol

Molecular Function: small GTPase binding; Rho guanyl-nucleotide exchange factor activity; guanyl-nucleotide exchange factor activity; metal ion binding

Biological Process: regulation of cell shape; regulation of small GTPase mediated signal transduction; filopodium formation; nerve growth factor receptor signaling pathway; positive regulation of apoptosis; small GTPase mediated signal transduction; cytoskeleton organization and biogenesis; actin cytoskeleton organization and biogenesis; positive regulation of GTPase activity
Show more

Research Articles on FGD3

1. Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-FGD3 antibody

 Reference Product  PubMed Publications
 CDC42 antibody  >5 publications with FGD3 and CDC42

Pathways associated with anti-FGD3 antibody

 Products by Pathway  Pathway Diagram
 Cell Death Signalling Via NRAGE, NRIF And NADE Pathway antibodies  Cell Death Signalling Via NRAGE, NRIF And NADE Pathway Diagram
 G Alpha (12/13) Signalling Events Pathway antibodies  G Alpha (12/13) Signalling Events Pathway Diagram
 GPCR Downstream Signaling Pathway antibodies  GPCR Downstream Signaling Pathway Diagram
 NRAGE Signals Death Through JNK Pathway antibodies  NRAGE Signals Death Through JNK Pathway Diagram
 Regulation Of Actin Cytoskeleton Pathway antibodies  Regulation Of Actin Cytoskeleton Pathway Diagram
 Regulation Of Actin Cytoskeleton Pathway antibodies  Regulation Of Actin Cytoskeleton Pathway Diagram
 Rho GTPase Cycle Pathway antibodies  Rho GTPase Cycle Pathway Diagram
 Signal Transduction Pathway antibodies  Signal Transduction Pathway Diagram
 Signaling By GPCR Pathway antibodies  Signaling By GPCR Pathway Diagram
 Signaling By Rho GTPases Pathway antibodies  Signaling By Rho GTPases Pathway Diagram

Diseases associated with anti-FGD3 antibody

 Disease Name  Pubmed Publications
 Chromosome Aberrations Antibodies  >2 publications with FGD3 and Chromosome Aberrations
 Urogenital Abnormalities Antibodies  >1 publications with FGD3 and Urogenital Abnormalities

Organs/Tissues associated with anti-FGD3 antibody

 Organ/Tissue Name  Pubmed Publications
 Bone Antibodies  >1 publications with FGD3 and Bone
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000