Rabbit Anti-FGD4 Polyclonal Antibody – Cat# MBS6298937

FGD4 Antibody (N-term) western blot analysis in human normal Uterus tissue lysates (35ug/lane).This demonstrates the FGD4 antibody detected the FGD4 protein (arrow).

FGD4 Antibody – Rabbit Polyclonal

Name: FGD4 Antibody; Polyclonal; Rabbit; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS6298937
Price: 1060 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6298937

This gene encodes a protein that is involved in the regulation of the actin cytoskeleton and cell shape. This protein contains an actin filament-binding domain, which together with its Dbl homology domain and one of its pleckstrin homology domains, can form… More details

$1060 / 0.2 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

FGD4, Polyclonal Antibody

Full Product Name

FGD4, NT (FGD4, FRABP, ZFYVE6, FYVE, RhoGEF and PH domain-containing protein 4, Actin filament-binding protein frabin, FGD1-related F-actin-binding protein, Zinc finger FYVE domain-containing protein 6) (FITC)

Product Gene Name

anti-FGD4 antibody

Product Synonym Names

FGD4; FRABP; ZFYVE6; FYVE; RhoGEF and PH domain-containing protein 4; Actin filament-binding protein frabin; FGD1-related F-actin-binding protein; Zinc finger FYVE domain-containing protein 6

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human

Form/Format

Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Fluorescein Isothiocyanate (FITC).

Purity/Purification

Purified by Protein A Affinity Chromatography.

Preparation and Storage

Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: FITC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Molecular Weight

86,626 Da

OMIM

609311

3D Structure

ModBase 3D Structure for Q96M96

Immunogen

FGD4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 156-186 amino acids from the N-terminal region of human FGD4.

Conjugate

FITC

Note

Preservative Free

Special Handling

Light sensitive

Product Categories/Family for anti-FGD4 antibody

Antibodies; Transcription Factors; Zinc (Ring) Finger

Applications Tested/Suitable for anti-FGD4 antibody

Western Blot (WB), FLISA

Application Notes for anti-FGD4 antibody

WB: 1:100-500
FLISA: 1:1,000
Applications are based on unconjugated antibody.

Product References and Citations for anti-FGD4 antibody

Rose, J. Phd, et al. Mol. Med. (2010). In press: Fabrizi, G.M., et al. Neurology 72(13):1160-1164(2009). Houlden, H., et al. Neurology 72(7):617-620(2009). Horlock, C., et al. Int. Arch. Allergy Immunol. 150(3):237-251(2009). Stendel, C., et al. Am. J. Hum. Genet. 81(1):158-164(2007).

Other Notes

Small volumes of anti-FGD4 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for FGD4 purchase

MBS6298937 is an antibody targeting FGD4. Also known as FGD4, NT (FGD4, FRABP, ZFYVE6, FYVE, RhoGEF and PH domain-containing protein 4, Actin filament-binding protein frabin, FGD1-related F-actin-binding protein, Zinc finger FYVE domain-containing protein 6) (FITC). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for FGD4. It may not necessarily be applicable to this product.

NCBI GI #

198041928

NCBI GeneID

121512

NCBI Accession #

NP_640334.2

UniProt Primary Accession #

Q96M96

UniProt Secondary Accession #

Q6ULS2; Q8TCP6

UniProt Related Accession #

Q96M96

GenBank Nucleotide #

NM_139241.2

NCBI Official Full Name

FYVE, RhoGEF and PH domain-containing protein 4

NCBI Official Synonym Full Names

FYVE, RhoGEF and PH domain containing 4

NCBI Official Symbol

FGD4

NCBI Official Synonym Symbols

CMT4H; FRABP; ZFYVE6

UniProt Protein Name

FYVE, RhoGEF and PH domain-containing protein 4

UniProt Synonym Protein Names

Actin filament-binding protein frabin; FGD1-related F-actin-binding protein; Zinc finger FYVE domain-containing protein 6

Protein Family

FYVE, RhoGEF and PH domain-containing protein

UniProt Gene Name

FGD4

UniProt Synonym Gene Names

FRABP; ZFYVE6

UniProt Entry Name

FGD4_HUMAN

NCBI Protein Information

FYVE, RhoGEF and PH domain-containing protein 4; FGD1 family, member 4; FGD1-related F-actin-binding protein; actin-filament binding protein frabin; zinc finger FYVE domain-containing protein 6

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-FGD4 antibody

Reference Product	PubMed Publications
CDC42 antibody	>10 publications with FGD4 and CDC42
GDAP1 antibody	>6 publications with FGD4 and GDAP1
SH3TC2 antibody	>6 publications with FGD4 and SH3TC2
SBF2 antibody	>3 publications with FGD4 and SBF2

Pathways associated with anti-FGD4 antibody

Products by Pathway	Pathway Diagram
Cell Death Signalling Via NRAGE, NRIF And NADE Pathway antibodies	Cell Death Signalling Via NRAGE, NRIF And NADE Pathway Diagram
G Alpha (12/13) Signalling Events Pathway antibodies	G Alpha (12/13) Signalling Events Pathway Diagram
GPCR Downstream Signaling Pathway antibodies	GPCR Downstream Signaling Pathway Diagram
NRAGE Signals Death Through JNK Pathway antibodies	NRAGE Signals Death Through JNK Pathway Diagram
Rho GTPase Cycle Pathway antibodies	Rho GTPase Cycle Pathway Diagram
Signal Transduction Pathway antibodies	Signal Transduction Pathway Diagram
Signaling By GPCR Pathway antibodies	Signaling By GPCR Pathway Diagram
Signaling By Rho GTPases Pathway antibodies	Signaling By Rho GTPases Pathway Diagram
Signalling By NGF Pathway antibodies	Signalling By NGF Pathway Diagram
P75 NTR Receptor-mediated Signalling Pathway antibodies	P75 NTR Receptor-mediated Signalling Pathway Diagram

Diseases associated with anti-FGD4 antibody

Disease Name	Pubmed Publications
Nervous System Diseases Antibodies	>13 publications with FGD4 and Nervous System Diseases
Carcinoma Antibodies	>3 publications with FGD4 and Carcinoma
Breast Neoplasms Antibodies	>2 publications with FGD4 and Breast Neoplasms
Neoplasms, Experimental Antibodies	>2 publications with FGD4 and Neoplasms, Experimental
Pain Antibodies	>2 publications with FGD4 and Pain
Charcot-Marie-Tooth Disease, Type 4H Antibodies	>2 publications with FGD4 and Charcot-Marie-Tooth Disease, Type 4H
Disease Models, Animal Antibodies	>1 publications with FGD4 and Disease Models, Animal
Necrosis Antibodies	>1 publications with FGD4 and Necrosis
Inflammation Antibodies	>1 publications with FGD4 and Inflammation

Organs/Tissues associated with anti-FGD4 antibody

Organ/Tissue Name	Pubmed Publications
Muscle Antibodies	>4 publications with FGD4 and Muscle
Brain Antibodies	>4 publications with FGD4 and Brain
Blood Antibodies	>3 publications with FGD4 and Blood