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FGL1 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6299207

Fibrinogen-like 1 is a member of the fibrinogen family. This protein is homologous to the carboxy terminus of the fibrinogen beta-and gamma-subunits which contains the four conserved cysteines of fibrinogens and fibrinogen related proteins. However, this… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
FGL1, Polyclonal Antibody
Full Product Name
FGL1, CT (FGL1, HFREP1, Fibrinogen-like protein 1, HP-041, Hepassocin, Hepatocyte-derived fibrinogen-related protein 1, Liver fibrinogen-related protein 1) (MaxLight 750)
Product Gene Name
Product Synonym Names
FGL1; HFREP1; Fibrinogen-like protein 1; HP-041; Hepassocin; Hepatocyte-derived fibrinogen-related protein 1; Liver fibrinogen-related protein 1
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight750.
Purity/Purification
Purified by Protein A and Peptide Affinity Chromatography.
Specificity
Recognizes human FGL1.
Preparation and Storage
Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: MaxLight750 conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
3D Structure
ModBase 3D Structure for Q08830
Immunogen
KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 218-247 in the C-terminal region of human FGL1.
Conjugate
MaxLight750
Note
Preservative Free

Product Categories/Family for anti-FGL1 antibody

Applications Tested/Suitable for anti-FGL1 antibody
Immunohistochemistry (IHC) Paraffin, ELISA (EIA), Western Blot (WB)
Application Notes for anti-FGL1 antibody
Applications are based on unconjugated antibody.

Western Blot (WB) of anti-FGL1 antibody

Western Blot analysis of HepG2 cell line lysate (35ug/lane) using MBS643661 at 1;1,000 dilution. This demonstrates the MBS643661 detected FGL1 protein (arrow).
Rabbit Anti-FGL1 Polyclonal Antibody – Cat# MBS6299207

Immunohistochemistry (IHC) of anti-FGL1 antibody

Immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissuea using MBS643661 followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the MBS643661 for immunohistochemistry.
Rabbit Anti-FGL1 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS6299207

Product References and Citations for anti-FGL1 antibody

1. Bailey, S.D., et al. Diabetes Care (2010) In press: 2. Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010). 3. Segat, L., et al. J. Gastroenterol. Hepatol. 24(12):1840-1846(2009). 4. Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009). 5. Yu, H.T., et al. J. Biol. Chem. 284(20):13335-13347(2009).

Other Notes

Small volumes of anti-FGL1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for FGL1 purchase

MBS6299207 is an antibody targeting FGL1. Also known as FGL1, CT (FGL1, HFREP1, Fibrinogen-like protein 1, HP-041, Hepassocin, Hepatocyte-derived fibrinogen-related protein 1, Liver fibrinogen-related protein 1) (MaxLight 750). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for FGL1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI Related Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
fibrinogen-like protein 1
NCBI Official Synonym Full Names
fibrinogen like 1
NCBI Official Symbol
FGL1
NCBI Official Synonym Symbols
HFREP1; HP-041; LFIRE1; LFIRE-1
UniProt Protein Name
Fibrinogen-like protein 1
UniProt Synonym Protein Names
HP-041; Hepassocin; Hepatocyte-derived fibrinogen-related protein 1; HFREP-1; Liver fibrinogen-related protein 1; LFIRE-1
UniProt Gene Name
FGL1
UniProt Synonym Gene Names
HFREP1; HFREP-1; LFIRE-1
NCBI Protein Information
fibrinogen-like protein 1

NCBI Summary for FGL1

Fibrinogen-like 1 is a member of the fibrinogen family. This protein is homologous to the carboxy terminus of the fibrinogen beta- and gamma- subunits which contains the four conserved cysteines of fibrinogens and fibrinogen related proteins. However, this protein lacks the platelet-binding site, cross-linking region and a thrombin-sensitive site which are necessary for fibrin clot formation. This protein may play a role in the development of hepatocellular carcinomas. Four alternatively spliced transcript variants encoding the same protein exist for this gene. [provided by RefSeq, Jul 2008]
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UniProt Comments for FGL1

Has hepatocyte mitogenic activity.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
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