Rabbit Anti-FPR2 Polyclonal Antibody – Cat# MBS2516802

Immunohistochemistry of paraffin-embedded Human cervical cancer tissue using FPR2 Polyclonal Antibody at dilution 1:17

FPR2 Antibody – Rabbit Polyclonal

Name: FPR2 Antibody; Polyclonal; Rabbit; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS2516802
Price: 160 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS2516802

Low affinity receptor for N-formyl-methionyl peptides, which are powerful neutrophils chemotactic factors. Binding of FMLP to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a… More details

$160 / 0.02 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

FPR2, Polyclonal Antibody

Full Product Name

FPR2 Polyclonal Antibody

Product Gene Name

anti-FPR2 antibody

Product Synonym Names

ALXR, HM63, FMLPX, FPR2A, FPRH1, FPRH2, FPRL1, LXA4R, FMLP-R-II

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human

Form/Format

PBS with 0.05% sodium azide, 50% glycerol, PH7.3

Purity/Purification

Affinity purification

Preparation and Storage

Store at -20 degree C. Avoid freeze / thaw cycles.

Immunogen

Synthetic peptide of human FPR2

Note

Centrifuge before opening to ensure complete recovery of vial contents.

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Applications Tested/Suitable for anti-FPR2 antibody

ELISA (EIA), Immunohistochemistry (IHC)

Application Notes for anti-FPR2 antibody

IHC: 1:20-1:100

Other Notes

Small volumes of anti-FPR2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for FPR2 purchase

MBS2516802 is an antibody targeting FPR2. Also known as FPR2 Polyclonal Antibody. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for FPR2. It may not necessarily be applicable to this product.

NCBI GI #

6679853

NCBI GeneID

14289

NCBI Accession #

NP_032065.1

UniProt Related Accession #

O88536

GenBank Nucleotide #

NM_008039.2

NCBI Official Full Name

formyl peptide receptor 2

NCBI Official Synonym Full Names

formyl peptide receptor 2

NCBI Official Symbol

Fpr2

NCBI Official Synonym Symbols

Fpr-rs2; E330010I07Rik

UniProt Protein Name

Formyl peptide receptor 2

UniProt Synonym Protein Names

Formylpeptide receptor-related sequence 2; Lipoxin A4 receptor-like protein; N-formylpeptide receptor-like 2

Protein Family

Formyl peptide receptor

UniProt Gene Name

Fpr2

UniProt Synonym Gene Names

Fpr-rs2

UniProt Entry Name

FPR2_MOUSE

NCBI Protein Information

formyl peptide receptor 2; N-formylpeptide receptor-like 2; formyl peptide receptor, related sequence 2; formylpeptide receptor-related sequence 2; lipoxin A4 receptor-like protein

UniProt Comments for FPR2

FPR2: Low affinity receptor for N-formyl-methionyl peptides, which are powerful neutrophils chemotactic factors. Binding of FMLP to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. The activation of LXA4R could result in an anti-inflammatory outcome counteracting the actions of proinflammatory signals such as LTB4 (leukotriene B4). Belongs to the G-protein coupled receptor 1 family.

Protein type: Motility/polarity/chemotaxis; GPCR, family 1; Membrane protein, integral; Membrane protein, multi-pass; Receptor, GPCR

Cellular Component: membrane; plasma membrane; integral to membrane

Molecular Function: G-protein coupled receptor activity; signal transducer activity; RAGE receptor binding; N-formyl peptide receptor activity; receptor activity

Biological Process: G-protein coupled receptor protein signaling pathway; G-protein signaling, coupled to IP3 second messenger (phospholipase C activating); chemotaxis; signal transduction

Research Articles on FPR2

1. FPR1 and FPR2 play an important role in the innate immune responses against Streptococcus pneumoniae within the central nervous system and the lack of the receptors leads to a dysregulation of the inflammatory response compared with wild-type mice.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-FPR2 antibody

Reference Product	PubMed Publications
Fpr1 antibody	>76 publications with FPR2 and Fpr1
Anxa1 antibody	>25 publications with FPR2 and Anxa1
Ccl5 antibody	>4 publications with FPR2 and Ccl5
Cxcl2 antibody	>3 publications with FPR2 and Cxcl2
Cxcl10 antibody	>2 publications with FPR2 and Cxcl10
App antibody	>2 publications with FPR2 and App
Cxcl12 antibody	>1 publications with FPR2 and Cxcl12

Pathways associated with anti-FPR2 antibody

Products by Pathway	Pathway Diagram
Class A/1 (Rhodopsin-like Receptors) Pathway antibodies	Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
Defective ACTH Causes Obesity And Pro-opiomelanocortinin Deficiency (POMCD) Pathway antibodies	Defective ACTH Causes Obesity And Pro-opiomelanocortinin Deficiency (POMCD) Pathway Diagram
Disease Pathway antibodies	Disease Pathway Diagram
Formyl Peptide Receptors Bind Formyl Peptides And Many Other Ligands Pathway antibodies	Formyl Peptide Receptors Bind Formyl Peptides And Many Other Ligands Pathway Diagram
G Alpha (i) Signalling Events Pathway antibodies	G Alpha (i) Signalling Events Pathway Diagram
G Alpha (q) Signalling Events Pathway antibodies	G Alpha (q) Signalling Events Pathway Diagram
GPCR Downstream Signaling Pathway antibodies	GPCR Downstream Signaling Pathway Diagram
GPCR Ligand Binding Pathway antibodies	GPCR Ligand Binding Pathway Diagram
GPCRs, Class A Rhodopsin-like Pathway antibodies	GPCRs, Class A Rhodopsin-like Pathway Diagram
Gastrin-CREB Signalling Pathway Via PKC And MAPK antibodies	Gastrin-CREB Signalling Pathway Via PKC And MAPK Diagram

Diseases associated with anti-FPR2 antibody

Disease Name	Pubmed Publications
Inflammation Antibodies	>194 publications with FPR2 and Inflammation
Necrosis Antibodies	>29 publications with FPR2 and Necrosis
Lung Diseases Antibodies	>27 publications with FPR2 and Lung Diseases
Vascular Diseases Antibodies	>17 publications with FPR2 and Vascular Diseases
Autoimmune Diseases Antibodies	>15 publications with FPR2 and Autoimmune Diseases
Lung Injury Antibodies	>9 publications with FPR2 and Lung Injury
Fibrosis Antibodies	>9 publications with FPR2 and Fibrosis
Respiratory Hypersensitivity Antibodies	>8 publications with FPR2 and Respiratory Hypersensitivity
Carcinoma Antibodies	>7 publications with FPR2 and Carcinoma
Respiratory Tract Infections Antibodies	>6 publications with FPR2 and Respiratory Tract Infections

Organs/Tissues associated with anti-FPR2 antibody

Organ/Tissue Name	Pubmed Publications
Bone Marrow Antibodies	>12 publications with FPR2 and Bone Marrow
Ovary Antibodies	>7 publications with FPR2 and Ovary
Inner Ear Antibodies	>1 publications with FPR2 and Inner Ear