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Frizzled (fz) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS535575

MBS535575 is an antibody targeting fz. Also known as Frizzled antibody. Reactive in Human. Host: Rabbit. Rabbit polyclonal Frizzled antibody More details

$1650 / 0.05 mg +2 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Frizzled (fz), Polyclonal Antibody
Full Product Name
Frizzled antibody
Product Gene Name
Product Synonym Names
Polyclonal Frizzled; Anti-Frizzled; FZD3; frizzled homolog fzd3; Frizzled 9; hFz9; fzd9; Fz9; Frizzled (Drosophila) homolog 3; frizzled-9; FzE6
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human
Form/Format
Purified by Immunoaffinity Chromatography and supplied in PBS with 0.1% NaN3.
Purity/Purification
Frizzled antibody was purified by affinity chromatography.
Concentration
1.0 mg/ml (lot specific)
Specificity
Human
Preparation and Storage
Store at 4 degree C for short term storage. Aliquot and store at -70 degree C for long term storage. Avoid repeated freeze/thaw cycles.
Molecular Weight
46,118 Da
Biohazard Information
This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling.
Immunogen
Frizzled antibody was raised in rabbit using a synthetic peptide conjugated to KLH as the immunogen.

Product Categories/Family for anti-fz antibody

Applications Tested/Suitable for anti-fz antibody
Immunohistochemistry (IHC) Paraffin
Application Notes for anti-fz antibody
IHC-P: 10 ug/ml

Other Notes

Small volumes of anti-fz antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for fz. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
frizzled, isoform C
NCBI Official Synonym Full Names
frizzled
NCBI Official Symbol
fz
NCBI Official Synonym Symbols
CG17697; CG3646; dFz; Dfz; DFz; Dfz1; DFz1; DFZ1; Dm Fz1; DmelCG17697; frz; Frz; Fz; FZ; fz1; Fz1; fz[[1]]
UniProt Protein Name
Frizzled
UniProt Synonym Protein Names
Frizzled-1; dFz1
Protein Family
UniProt Gene Name
fz
UniProt Synonym Gene Names
dFz1
UniProt Entry Name
FRIZ_DROME
NCBI Protein Information
CG17697 gene product from transcript CG17697-RA

UniProt Comments for fz

Receptor for Wnt proteins. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase. Both pathways seem to involve interactions with G-proteins. Required to coordinate the cytoskeletons of epidermal cells to produce a parallel array of cuticular hairs and bristles.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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