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FXR2 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3904136

FXR2 is a RNA binding protein containing two KH domains and one RCG box, which is similar to FMRP and FXR1. It associates with polyribosomes, predominantly with 60S large ribosomal subunits. FXR2 may self-associate or interact with FMRP and FXR1. It may have… More details

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Testing Data View PDF
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Product Overview

Online Datasheet in PDF
Product Name
FXR2, Polyclonal Antibody
Full Product Name
Rabbit anti-FXR2 Antibody, Affinity Purified
Product Gene Name
Product Synonym Names
FMR1L2; fragile X mental retardation syndrome-related protein 2; fragile X mental retardation, autosomal homolog 2; fragile X-mental retardation 1-like 2; FXR2P; Fragile X mental retardation syndrome-related protein 2; FMR1 autosomal homolog 2
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human
Form/Format
Liquid. Whole IgG. Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide
Purity/Purification
Antigen Affinity Purified
Concentration
1000ug/ml (lot specific)
Preparation and Storage
Store at 2-8 degree C
Shelf Life: 1 year from date of receipt
Molecular Weight
74,223 Da
Chromosome Location
Chromosome: 17; NC_000017.10 (7494548..7518215, complement). Location: 17p13.1
OMIM
605339
3D Structure
ModBase 3D Structure for P51116
Immunogen
Between 623 and C-terminus
Conjugation
Unconjugated

Product Categories/Family for anti-FXR2 antibody

Applications Tested/Suitable for anti-FXR2 antibody
Western Blot (WB), Immunoprecipitation (IP)
Application Notes for anti-FXR2 antibody
WB: 1:2000-1:10,000
IP: 6ug/mg lysate

Immunoprecipitation (IP) of anti-FXR2 antibody

Detection of human FXR2 by western blot of immunoprecipitates. Samples: Whole cell lysate (1 mg for IP; 20% of IP loaded) from HEK293T cells. Antibodies: Affinity purified rabbit anti-FXR2 antibody MBS3904136 (lot MBS3904136-1) used for IP at 6 ug/mg lysate. FXR2 was also immunoprecipitated by rabbit anti-FXR2 antibody MBS3904137. For blotting immunoprecipitated FXR2, MBS3904136 was used at 1 ug/ml. Detection: Chemiluminescence with an exposure time of 30 seconds.
Rabbit Anti-FXR2 Polyclonal Antibody – Cat# MBS3904136

Western Blot (WB) of anti-FXR2 antibody

Detection of human FXR2 by western blot. Samples: Whole cell lysate from HEK293T (15 and 50 ug), HeLa (50ug), and Jurkat (50ug) cells. Antibodies: Affinity purified rabbit anti-FXR2 antibody MBS3904136 (lot MBS3904136-1) used for WB at 0.1 ug/ml. Detection: Chemiluminescence with an exposure time of 30 seconds.
Rabbit Anti-FXR2 Polyclonal Antibody, Western Blot (WB) – Cat# MBS3904136

Other Notes

Small volumes of anti-FXR2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for FXR2 purchase

MBS3904136 is an antibody targeting FXR2. Also known as Rabbit anti-FXR2 Antibody, Affinity Purified. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for FXR2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
fragile X mental retardation syndrome-related protein 2
NCBI Official Synonym Full Names
fragile X mental retardation, autosomal homolog 2
NCBI Official Symbol
FXR2
NCBI Official Synonym Symbols
FXR2P; FMR1L2
UniProt Protein Name
Fragile X mental retardation syndrome-related protein 2
UniProt Gene Name
FXR2
UniProt Synonym Gene Names
FMR1L2
UniProt Entry Name
FXR2_HUMAN
NCBI Protein Information
fragile X mental retardation syndrome-related protein 2; fragile X-mental retardation 1-like 2

NCBI Summary for FXR2

The protein encoded by this gene is a RNA binding protein containing two KH domains and one RCG box, which is similar to FMRP and FXR1. It associates with polyribosomes, predominantly with 60S large ribosomal subunits. This encoded protein may self-associate or interact with FMRP and FXR1. It may have a role in the development of fragile X mental retardation syndrome. [provided by RefSeq, Jul 2008]
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UniProt Comments for FXR2

FXR2: RNA-binding protein. Interacts with FMR1 and FXR1. Interacts with CYFIP2 but not with CYFIP1. Interacts with TDRD3. Belongs to the FMR1 family.

Protein type: RNA-binding

Chromosomal Location of Human Ortholog: 17p13.1

Cellular Component: polysome; membrane; cytoplasm; nucleus

Molecular Function: mRNA binding; identical protein binding; protein binding; RNA binding

Biological Process: negative regulation of translation
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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