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GABRA3 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS8555982

MBS8555982 is an antibody targeting GABRA3. Also known as GABRA3 (N-Term) Rabbit pAb. Reactive in Human. Host: Rabbit. More details

$380 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
GABRA3, Polyclonal Antibody
Full Product Name
GABRA3 (N-Term) Rabbit pAb
Product Gene Name
anti-GABRA3 antibody
Product Synonym Names
Gamma-aminobutyric acid receptor subunit alpha-3; GABA(A) receptor subunit alpha-3; GABRA3
Clonality
Polyclonal
Isotype
Ig
Clone Number
RB50699
Host
Rabbit
Species Reactivity
Human
Purity/Purification
Affinity Purified
OMIM
305660
3D Structure
ModBase 3D Structure for P34903
Immunogen
This GABRA3 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 28-61 amino acids from the N-terminal region of human GABRA3.
Cellular Localization
Cell Junction, Cell Membrane, Membrane, Postsynaptic Cell Membrane, Synapse
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-GABRA3 antibody
Western Blot (WB)
Application Notes for anti-GABRA3 antibody
WB: 1:500-1:1000

Other Notes

Small volumes of anti-GABRA3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for GABRA3. It may not necessarily be applicable to this product.

NCBI GI #
4557603
NCBI GeneID
2556
NCBI Accession #
NP_000799.1
UniProt Primary Accession #
P34903
UniProt Related Accession #
P34903
GenBank Nucleotide #
NP_000799.1
NCBI Official Full Name
gamma-aminobutyric acid receptor subunit alpha-3
NCBI Official Synonym Full Names
gamma-aminobutyric acid type A receptor alpha3 subunit
NCBI Official Symbol
GABRA3
UniProt Protein Name
Gamma-aminobutyric acid receptor subunit alpha-3
UniProt Synonym Protein Names
GABA(A) receptor subunit alpha-3
Protein Family
Gamma-aminobutyric acid receptor
UniProt Gene Name
GABRA3
UniProt Entry Name
GBRA3_HUMAN
NCBI Protein Information
gamma-aminobutyric acid receptor subunit alpha-3

NCBI Summary for GABRA3

GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. [provided by RefSeq, Jul 2008]
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UniProt Comments for GABRA3

GABRA3: GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel. Belongs to the ligand-gated ion channel (TC 1.A.9) family. Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily. GABRA3 sub-subfamily.

Protein type: Membrane protein, integral; Transporter; Membrane protein, multi-pass; Transporter, ion channel

Chromosomal Location of Human Ortholog: Xq28

Cellular Component: postsynaptic membrane; integral to plasma membrane; plasma membrane; cell junction

Molecular Function: chloride channel activity; GABA-A receptor activity; benzodiazepine receptor activity; extracellular ligand-gated ion channel activity

Biological Process: synaptic transmission; transport; transmembrane transport; gamma-aminobutyric acid signaling pathway
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Research Articles on GABRA3

1. The GABRA3 found distribute in intercalated nucleui of amygdala and dentate gyrus.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-GABRA3 antibody

 Reference Product  PubMed Publications
 GABRA2 antibody  >15 publications with GABRA3 and GABRA2
 GABRA1 antibody  >12 publications with GABRA3 and GABRA1
 GABRB3 antibody  >7 publications with GABRA3 and GABRB3
 GABRA5 antibody  >5 publications with GABRA3 and GABRA5
 GABRA6 antibody  >4 publications with GABRA3 and GABRA6
 GABRA4 antibody  >3 publications with GABRA3 and GABRA4
 GABRG2 antibody  >3 publications with GABRA3 and GABRG2
 GABRB2 antibody  >2 publications with GABRA3 and GABRB2
 GABRB1 antibody  >1 publications with GABRA3 and GABRB1
 GABRG3 antibody  >1 publications with GABRA3 and GABRG3

Pathways associated with anti-GABRA3 antibody

 Products by Pathway  Pathway Diagram
 GABA A Receptor Activation Pathway antibodies  GABA A Receptor Activation Pathway Diagram
 GABA Receptor Activation Pathway antibodies  GABA Receptor Activation Pathway Diagram
 GABAergic Synapse Pathway antibodies  GABAergic Synapse Pathway Diagram
 GABAergic Synapse Pathway antibodies  GABAergic Synapse Pathway Diagram
 Ion Channel Transport Pathway antibodies  Ion Channel Transport Pathway Diagram
 Ligand-gated Ion Channel Transport Pathway antibodies  Ligand-gated Ion Channel Transport Pathway Diagram
 Morphine Addiction Pathway antibodies  Morphine Addiction Pathway Diagram
 Morphine Addiction Pathway antibodies  Morphine Addiction Pathway Diagram
 Neuroactive Ligand-receptor Interaction Pathway antibodies  Neuroactive Ligand-receptor Interaction Pathway Diagram
 Neuroactive Ligand-receptor Interaction Pathway antibodies  Neuroactive Ligand-receptor Interaction Pathway Diagram

Diseases associated with anti-GABRA3 antibody

 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >23 publications with GABRA3 and Nervous System Diseases
 Anxiety Disorders Antibodies  >6 publications with GABRA3 and Anxiety Disorders
 Disease Models, Animal Antibodies  >5 publications with GABRA3 and Disease Models, Animal
 Depressive Disorder Antibodies  >4 publications with GABRA3 and Depressive Disorder
 Seizures Antibodies  >2 publications with GABRA3 and Seizures
 Lung Neoplasms Antibodies  >2 publications with GABRA3 and Lung Neoplasms
 Depressive Disorder, Major Antibodies  >2 publications with GABRA3 and Depressive Disorder, Major
 Poisoning Antibodies  >1 publications with GABRA3 and Poisoning
 Alcoholism Antibodies  >1 publications with GABRA3 and Alcoholism
 Liver Diseases Antibodies  >1 publications with GABRA3 and Liver Diseases

Organs/Tissues associated with anti-GABRA3 antibody

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >36 publications with GABRA3 and Brain
 Testis Antibodies  >1 publications with GABRA3 and Testis
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