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GDA Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6301773

GDA is an enzyme that catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia. More details

$1025 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
GDA, Polyclonal Antibody
Full Product Name
GDA, NT (GDA, KIAA1258, Guanine deaminase, Guanine aminohydrolase, p51-nedasin) (MaxLight 750)
Product Gene Name
Product Synonym Names
GDA; KIAA1258; Guanine deaminase; Guanine aminohydrolase; p51-nedasin
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight750.
Purity/Purification
Purified by Protein A and Peptide Affinity Chromatography.
Specificity
Recognizes human GDA.
Preparation and Storage
Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: MaxLight750 conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molecular Weight
52,837 Da
OMIM
139260
3D Structure
ModBase 3D Structure for Q9Y2T3
Immunogen
KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 94-122 in the N-terminal region of human GDA.
Conjugate
MaxLight750
Note
Preservative Free

Product Categories/Family for anti-GDA antibody

Applications Tested/Suitable for anti-GDA antibody
Western Blot (WB), Flow Cytometry (FC/FACS), FLISA
Application Notes for anti-GDA antibody
Applications are based on unconjugated antibody.

Western Blot (WB) of anti-GDA antibody

Western Blot analysis in HL-60 cell line lysates (35ug/lane) usingMBS642815. GDA (arrow) was detected usingMBS642815.
Rabbit Anti-GDA Polyclonal Antibody – Cat# MBS6301773

Flow Cytometry (FC/FACS) of anti-GDA antibody

Flow Cytometric analysis of HL-60 cells using MBS642815 (right histogram) compared to a negative control cell (left histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Rabbit Anti-GDA Polyclonal Antibody, Flow Cytometry (FC/FACS) – Cat# MBS6301773

Product References and Citations for anti-GDA antibody

1. Akum, B.F., et al. Nat. Neurosci. 7(2):145-152(2004). 2. Kuwahara, H., et al. J. Biol. Chem. 274(45):32204-32214(1999). 3. Firestein, B.L., et al. Neuron 24(3):659-672(1999)

Other Notes

Small volumes of anti-GDA antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for GDA purchase

MBS6301773 is an antibody targeting GDA. Also known as GDA, NT (GDA, KIAA1258, Guanine deaminase, Guanine aminohydrolase, p51-nedasin) (MaxLight 750). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for GDA. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
guanine deaminase isoform a
NCBI Official Synonym Full Names
guanine deaminase
NCBI Official Symbol
GDA
NCBI Official Synonym Symbols
CYPIN; GUANASE; NEDASIN
UniProt Protein Name
Guanine deaminase
UniProt Synonym Protein Names
Guanine aminohydrolase; GAH; p51-nedasin
UniProt Gene Name
GDA
UniProt Synonym Gene Names
KIAA1258; Guanase; Guanine aminase; GAH
UniProt Entry Name
GUAD_HUMAN
NCBI Protein Information
guanine deaminase; GAH; cytoplasmic PSD95 interactor; guanine aminase; guanine aminohydrolase; p51-nedasin

NCBI Summary for GDA

This gene encodes an enzyme responsible for the hydrolytic deamination of guanine. Studies in rat ortholog suggest this gene plays a role in microtubule assembly. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011]

UniProt Comments for GDA

GDA: Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia. Belongs to the ATZ/TRZ family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 3.5.4.3; Nucleotide Metabolism - purine; Hydrolase

Chromosomal Location of Human Ortholog: 9q21.13

Cellular Component: intracellular; cytosol

Molecular Function: guanine deaminase activity; zinc ion binding

Biological Process: nervous system development; nucleobase, nucleoside and nucleotide metabolic process; nucleobase, nucleoside, nucleotide and nucleic acid metabolic process; purine nucleotide catabolic process; guanine catabolic process; purine base metabolic process
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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