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GGT7 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6302174

This gene is a member of a gene family that encodes enzymes involved in both the metabolism of glutathione and in the transpeptidation of amino acids. Changes in the activity of gamma-glutamyltransferase may signal preneoplastic or toxic conditions in the… More details

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Sample Manual Insert View PDF
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Testing Data View PDF
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Product Overview

Online Datasheet in PDF
Product Name
GGT7, Polyclonal Antibody
Full Product Name
GGT7, NT (GGT7, GGTL3, GGTL5, Gamma-glutamyltransferase 7, Gamma-glutamyltransferase-like 3, Gamma-glutamyltransferase-like 5, Gamma-glutamyltranspeptidase 7, Glutathione hydrolase 7, Gamma-glutamyltransferase 7 heavy chain, Gamma-glutamyltransferase 7 li
Product Gene Name
Product Synonym Names
GGT7; GGTL3; GGTL5; Gamma-glutamyltransferase 7; Gamma-glutamyltransferase-like 3; Gamma-glutamyltransferase-like 5; Gamma-glutamyltranspeptidase 7; Glutathione hydrolase 7; Gamma-glutamyltransferase 7 heavy chain; Gamma-glutamyltransferase 7 light chain
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Fluorescein Isothiocyanate (FITC).
Purity/Purification
Purified by Protein A Affinity Chromatography.
Preparation and Storage
Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: FITC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
70,467 Da
Chromosome Location
Chromosome: 20; NC_000020.10 (33432523..33460661, complement). Location: 20q11.22
OMIM
612342
3D Structure
ModBase 3D Structure for Q9UJ14
Immunogen
GGT7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 23-53 amino acids from the N-terminal region of human GGT7.
Conjugate
FITC
Note
Preservative Free
Special Handling
Light sensitive

Product Categories/Family for anti-GGT7 antibody

Applications Tested/Suitable for anti-GGT7 antibody
Immunohistochemistry (IHC), FLISA, Western Blot (WB)
Application Notes for anti-GGT7 antibody
IHC: 1:10-50
FLISA: 1:1,000
WB: 1:100-500
Applications are based on unconjugated antibody.

Western Blot (WB) of anti-GGT7 antibody

GGT7 Antibody (N-term) western blot analysis in uterus tumor cell line lysates (35ug/lane).This demonstrates the GGT7 antibody detected the GGT7 protein (arrow).
Rabbit Anti-GGT7 Polyclonal Antibody – Cat# MBS6302174

Immunohistochemistry (IHC) of anti-GGT7 antibody

GGT7 Antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of GGT7 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.
Rabbit Anti-GGT7 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS6302174

Product References and Citations for anti-GGT7 antibody

Rose, J. Phd, et al. Mol. Med. (2010). In press: Heisterkamp, N., et al. Hum. Genet. 123(4):321-332(2008). He, X., et al. Biochem. Biophys. Res. Commun. 297(3):528-536(2002). Figlewicz, D.A., et al. Genomics 17(2):299-305(1993).

Other Notes

Small volumes of anti-GGT7 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for GGT7 purchase

MBS6302174 is an antibody targeting GGT7. Also known as GGT7, NT (GGT7, GGTL3, GGTL5, Gamma-glutamyltransferase 7, Gamma-glutamyltransferase-like 3, Gamma-glutamyltransferase-like 5, Gamma-glutamyltranspeptidase 7, Glutathione hydrolase 7, Gamma-glutamyltransferase 7 heavy chain, Gamma-glutamyltransferase 7 li. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for GGT7. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
gamma-glutamyltransferase 7
NCBI Official Synonym Full Names
gamma-glutamyltransferase 7
NCBI Official Symbol
GGT7
NCBI Official Synonym Symbols
GGT4; GGTL3; GGTL5; D20S101; dJ18C9.2
UniProt Protein Name
Gamma-glutamyltransferase 7
UniProt Synonym Protein Names
Gamma-glutamyltransferase-like 3; Gamma-glutamyltransferase-like 5; Gamma-glutamyltranspeptidase 7; Glutathione hydrolase 7
UniProt Gene Name
GGT7
UniProt Synonym Gene Names
GGTL3; GGTL5; GGT 7
UniProt Entry Name
GGT7_HUMAN
NCBI Protein Information
gamma-glutamyltransferase 7; GGT 7; glutathione hydrolase 7; gamma-glutamyltransferase 4; gamma-glutamyltranspeptidase 7; gamma-glutamyltransferase-like 3; gamma-glutamyltransferase-like 5; gamma-glutamyltranspeptidase-like 3

UniProt Comments for GGT7

GGTL3: Cleaves glutathione conjugates. Belongs to the gamma-glutamyltransferase family. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: Other Amino Acids Metabolism - glutathione; EC 3.4.19.13; Other Amino Acids Metabolism - selenoamino acid; Transferase; Other Amino Acids Metabolism - cyanoamino acid; Lipid Metabolism - arachidonic acid; EC 2.3.2.2; Membrane protein, integral; Other Amino Acids Metabolism - taurine and hypotaurine

Chromosomal Location of Human Ortholog: 20q11.22

Cellular Component: anchored to external side of plasma membrane; integral to membrane

Molecular Function: gamma-glutamyltransferase activity

Biological Process: leukotriene biosynthetic process; glutathione metabolic process; glutathione biosynthetic process; proteolysis
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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