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GIPC1 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS7051983

MBS7051983 is an antibody targeting GIPC1. Also known as GIPC1 Antibody, FITC conjugated. Reactive in Human. Host: Rabbit. May be involved in G protein-linked signaling. More details

$230 / 0.05 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
GIPC1, Polyclonal Antibody
Full Product Name
GIPC1 Antibody, FITC conjugated
Product Gene Name
anti-GIPC1 antibody
Product Synonym Names
PDZ domain-containing protein GIPC1; GAIP C-terminus-interacting protein; RGS-GAIP-interacting protein; RGS19-interacting protein 1; Synectin; Tax interaction protein 2; TIP-2; GIPC1; C19orf3; GIPC; RGS19IP1
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Liquid
Purity/Purification
>95%, Protein G purified
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
Matching Pairs
Unconjugated Antibody: GIPC1 (MBS7051981)
FITC Conjugated Antibody: GIPC1 (MBS7051983)
Molecular Weight
26,072 Da
OMIM
AF089816 mRNA
3D Structure
ModBase 3D Structure for O14908
Immunogen
Recombinant Human PDZ domain-containing protein GIPC1 protein (7-74AA)
Conjugation
FITC
Preservative
0.03% Proclin 300
Constituents
50% Glycerol, 0.01M PBS, pH 7.4
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-GIPC1 antibody
ELISA (EIA)

Other Notes

Small volumes of anti-GIPC1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for GIPC1. It may not necessarily be applicable to this product.

NCBI GI #
5031715
NCBI GeneID
10755
NCBI Accession #
NP_005707.1
UniProt Primary Accession #
O14908
UniProt Secondary Accession #
Q9BTC9; A8K4I3; A8MZG3
UniProt Related Accession #
O14908
GenBank Nucleotide #
NM_005716.3
NCBI Official Full Name
PDZ domain-containing protein GIPC1 isoform 1
NCBI Official Synonym Full Names
GIPC PDZ domain containing family member 1
NCBI Official Symbol
GIPC1
NCBI Official Synonym Symbols
NIP; GIPC; IIP-1; TIP-2; SEMCAP; C19orf3; Hs.6454; GLUT1CBP; RGS19IP1; SYNECTIN; SYNECTIIN
UniProt Protein Name
PDZ domain-containing protein GIPC1
UniProt Synonym Protein Names
GAIP C-terminus-interacting protein; RGS-GAIP-interacting protein; RGS19-interacting protein 1; Synectin; Tax interaction protein 2; TIP-2
Protein Family
PDZ domain-containing protein
UniProt Gene Name
GIPC1
UniProt Synonym Gene Names
C19orf3; GIPC; RGS19IP1; TIP-2
NCBI Protein Information
PDZ domain-containing protein GIPC1

NCBI Summary for GIPC1

GIPC1 is a scaffolding protein that regulates cell surface receptor expression and trafficking (Lee et al., 2008 [PubMed 18775991]).[supplied by OMIM, Apr 2009]

UniProt Comments for GIPC1

GIPC1: May be involved in G protein-linked signaling. Belongs to the GIPC family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: GAPs; GAPs, misc.; Motility/polarity/chemotaxis; Vesicle

Chromosomal Location of Human Ortholog: 19p13.12

Cellular Component: cell cortex; cell-cell adherens junction; cytoplasm; cytoplasmic vesicle; cytosol; dendritic shaft; dendritic spine; membrane; synaptic vesicle; vesicle membrane

Molecular Function: actin binding; myosin binding; protein binding; protein homodimerization activity; receptor binding

Biological Process: endothelial cell migration; glutamate secretion; negative regulation of proteasomal ubiquitin-dependent protein catabolic process; positive regulation of cytokinesis; positive regulation of transforming growth factor beta receptor signaling pathway; protein targeting; regulation of protein stability; regulation of synaptic plasticity; synaptic transmission
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Research Articles on GIPC1

1. Drd3 palmitoylation acts as a molecular switch for Drd3-biased signaling via a GIPC1-dependent route, which is likely to affect the mode of action of antipsychotic drugs.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-GIPC1 antibody

 Reference Product  PubMed Publications
 RGS19 antibody  >6 publications with GIPC1 and RGS19
 IGF1R antibody  >5 publications with GIPC1 and IGF1R
 MYO6 antibody  >5 publications with GIPC1 and MYO6
 NRP1 antibody  >4 publications with GIPC1 and NRP1
 NGF antibody  >2 publications with GIPC1 and NGF
 NTRK2 antibody  >2 publications with GIPC1 and NTRK2
 DRD2 antibody  >1 publications with GIPC1 and DRD2
 SLC2A1 antibody  >1 publications with GIPC1 and SLC2A1
 SDC4 antibody  >1 publications with GIPC1 and SDC4

Pathways associated with anti-GIPC1 antibody

 Products by Pathway  Pathway Diagram
 Neurotrophic Factor-mediated Trk Receptor Signaling Pathway antibodies  Neurotrophic Factor-mediated Trk Receptor Signaling Pathway Diagram
 Syndecan-4-mediated Signaling Events Pathway antibodies  Syndecan-4-mediated Signaling Events Pathway Diagram
 TGF-beta Receptor Signaling Pathway antibodies  TGF-beta Receptor Signaling Pathway Diagram

Diseases associated with anti-GIPC1 antibody

 Disease Name  Pubmed Publications
 Breast Neoplasms Antibodies  >14 publications with GIPC1 and Breast Neoplasms
 Ovarian Neoplasms Antibodies  >5 publications with GIPC1 and Ovarian Neoplasms
 Cardiovascular Diseases Antibodies  >3 publications with GIPC1 and Cardiovascular Diseases
 Prostatic Neoplasms Antibodies  >2 publications with GIPC1 and Prostatic Neoplasms
 Heart Diseases Antibodies  >2 publications with GIPC1 and Heart Diseases
 Insulin Resistance Antibodies  >1 publications with GIPC1 and Insulin Resistance
 Inflammation Antibodies  >1 publications with GIPC1 and Inflammation
 Kidney Diseases Antibodies  >1 publications with GIPC1 and Kidney Diseases
 Nervous System Diseases Antibodies  >1 publications with GIPC1 and Nervous System Diseases
 Abnormalities, Drug-Induced Antibodies  >1 publications with GIPC1 and Abnormalities, Drug-Induced

Organs/Tissues associated with anti-GIPC1 antibody

 Organ/Tissue Name  Pubmed Publications
 Lung Antibodies  >8 publications with GIPC1 and Lung
 Brain Antibodies  >8 publications with GIPC1 and Brain
 Vascular Antibodies  >6 publications with GIPC1 and Vascular
 Kidney Antibodies  >5 publications with GIPC1 and Kidney
 Heart Antibodies  >5 publications with GIPC1 and Heart
 Prostate Antibodies  >4 publications with GIPC1 and Prostate
 Muscle Antibodies  >3 publications with GIPC1 and Muscle
 Ovary Antibodies  >3 publications with GIPC1 and Ovary
 Intestine Antibodies  >2 publications with GIPC1 and Intestine
 Stomach Antibodies  >2 publications with GIPC1 and Stomach
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