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GJB7 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6456328

MBS6456328 is an antibody targeting GJB7. Also known as GJB7 (Gap junction beta-7 Protein, Connexin-25, Cx25, GJB7, CX25) (APC). Reactive in Human. Host: Rabbit. More details

$1060 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
GJB7, Polyclonal Antibody
Full Product Name
GJB7 (Gap junction beta-7 Protein, Connexin-25, Cx25, GJB7, CX25) (APC)
Product Gene Name
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Allophycocyanin (APC).
Purity/Purification
Purified
Specificity
Recognizes human GJB7. Species Crossreactivity: human
Preparation and Storage
Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: APC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molecular Weight
25,860 Da
Chromosome Location
Chromosome: 6; NC_000006.11 (87992697..88038996, complement). Location: 6q15
OMIM
611921
3D Structure
ModBase 3D Structure for Q6PEY0
Immunogen
Synthetic peptide corresponding to GJB7.
Conjugate
APC
Note
Preservative Free
Applications Tested/Suitable for anti-GJB7 antibody
Western Blot (WB)
Application Notes for anti-GJB7 antibody
WB: 1:1000
Applications are based on unconjugated antibody.

Product References and Citations for anti-GJB7 antibody

Willecke K., et al. Biol. Chem. 383:725-737(2002). Ota T., et al. Nat. Genet. 36:40-45(2004). Mungall A.J., et al. Nature 425:805-811(2003). Bondarev I., et al. Cell Commun. Adhes. 8:167-171(2001). Soehl G., et al. Cell Commun. Adhes. 10:27-36(2003).

Other Notes

Small volumes of anti-GJB7 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for GJB7. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
gap junction beta-7 protein
NCBI Official Synonym Full Names
gap junction protein, beta 7, 25kDa
NCBI Official Symbol
GJB7
NCBI Official Synonym Symbols
CX25; bA136M9.1; connexin25
UniProt Protein Name
Gap junction beta-7 protein
UniProt Synonym Protein Names
Connexin-25
UniProt Gene Name
GJB7
UniProt Synonym Gene Names
CX25; Cx25
UniProt Entry Name
CXB7_HUMAN
NCBI Protein Information
gap junction beta-7 protein; connexin 25; connexin-25

NCBI Summary for GJB7

Connexins, such as GJB7, are involved in the formation of gap junctions, intercellular conduits that directly connect the cytoplasms of contacting cells. Each gap junction channel is formed by docking of 2 hemichannels, each of which contains 6 connexin subunits (Sohl et al., 2003 [PubMed 12881038]).[supplied by OMIM, Mar 2008]
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UniProt Comments for GJB7

GJB7: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. Belongs to the connexin family. Beta-type (group I) subfamily.

Protein type: Membrane protein, multi-pass; Membrane protein, integral

Chromosomal Location of Human Ortholog: 6q15

Cellular Component: connexon complex; integral to membrane

Biological Process: cell communication
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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