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GJC3 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3203236

This is a rabbit polyclonal antibody against GJC3. It was validated on Western BlotTarget Description: This gene encodes a gap junction protein. The encoded protein, also known as a connexin, plays a role in formation of gap junctions, which provide direct… More details

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Testing Data View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
GJC3, Polyclonal Antibody
Full Product Name
GJC3 antibody - middle region
Product Gene Name
Product Synonym Gene Name
CX29; CX30.2; CX31.3; GJE1
Immunogen Sequence
Synthetic peptide located within the following region: WHWELSGKGK EEETLIQGRE GNTDVPGAGS LRLLWAYVAQ LGARLVLEGA A
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human
Form/Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Purity/Purification
Affinity Purified
Preparation and Storage
For short term use, store at 2-8 degree C up to 1 week. For long term storage, store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Antibody/Peptide Pairs
GJC3 peptide (MBS3228208) is used for blocking the activity of GJC3 antibody (MBS3203236)
Molecular Weight
31kDa
OMIM
611925
3D Structure
ModBase 3D Structure for Q8NFK1
Homology
Human: 100%
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human GJC3
Applications Tested/Suitable for anti-GJC3 antibody
Western Blot (WB)

Western Blot (WB) of anti-GJC3 antibody

WB Suggested Anti-GJC3 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:312500
Positive Control: PANC1 cell lysate
Rabbit Anti-GJC3 Polyclonal Antibody – Cat# MBS3203236

Other Notes

Small volumes of anti-GJC3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for GJC3 purchase

MBS3203236 is an antibody targeting GJC3. Also known as GJC3 antibody - middle region. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for GJC3. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
gap junction gamma-3 protein
NCBI Official Synonym Full Names
gap junction protein gamma 3
NCBI Official Symbol
GJC3
NCBI Official Synonym Symbols
CX29; GJE1; CX30.2; CX31.3
UniProt Protein Name
Gap junction gamma-3 protein
UniProt Synonym Protein Names
Connexin-30.2; Cx30.2; Connexin-31.3; Cx31.3; Gap junction epsilon-1 protein
UniProt Gene Name
GJC3
UniProt Synonym Gene Names
GJE1; Cx30.2; Cx31.3
UniProt Entry Name
CXG3_HUMAN
NCBI Protein Information
gap junction gamma-3 protein

NCBI Summary for GJC3

This gene encodes a gap junction protein. The encoded protein, also known as a connexin, plays a role in formation of gap junctions, which provide direct connections between neighboring cells. Mutations in this gene have been reported to be associated with nonsyndromic hearing loss.[provided by RefSeq, Feb 2010]
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UniProt Comments for GJC3

GJC3: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. Belongs to the connexin family. Gamma-type subfamily.

Protein type: Membrane protein, integral; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 7q22.1

Cellular Component: connexon complex; integral to membrane; myelin sheath

Molecular Function: protein homodimerization activity

Biological Process: myelination; sensory perception of sound; cell communication
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-GJC3 antibody

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