Rabbit Anti-GJC3 Polyclonal Antibody – Cat# MBS6302330

GJC3 Antibody – Rabbit Polyclonal

Name: GJC3 Antibody; Polyclonal; Rabbit; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS6302330
Price: 1025 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6302330

This gene encodes a gap junction protein. The encoded protein, also known as a connexin, plays a role in formation of gap junctions, which provide direct connections between neighboring cells. Mutations in this gene have been reported to be associated with… More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

GJC3, Polyclonal Antibody

Full Product Name

GJC3, CT (GJC3, GJE1, Gap junction gamma-3 protein, Connexin-30.2, Connexin-31.3, Gap junction epsilon-1 protein) (MaxLight 405)

Product Gene Name

anti-GJC3 antibody

Product Synonym Names

GJC3; GJE1; Gap junction gamma-3 protein; Connexin-30.2; Connexin-31.3; Gap junction epsilon-1 protein

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human

Form/Format

Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight405.

Purity/Purification

Purified by Protein A Affinity Chromatography.

Preparation and Storage

Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: MaxLight405 conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Molecular Weight

31,299 Da

Chromosome Location

Chromosome: 7; NC_000007.13 (99520892..99527243, complement). Location: 7q22.1

OMIM

611925

3D Structure

ModBase 3D Structure for Q8NFK1

Immunogen

GJC3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 251-278 amino acids from the C-terminal region of human GJC3.

Conjugate

MaxLight405

Note

Preservative Free

Product Categories/Family for anti-GJC3 antibody

Antibodies; Connexin; Junction Proteins

Applications Tested/Suitable for anti-GJC3 antibody

Western Blot (WB), FLISA

Application Notes for anti-GJC3 antibody

WB: 1:100-500
FLISA: 1:1,000
Applications are based on unconjugated antibody.

Product References and Citations for anti-GJC3 antibody

Yang, J.J., et al. Hum. Genet. 128(3):303-313(2010). Ramchander, P.V., et al. Genet Test Mol Biomarkers 14(4):539-541(2010). Hong, H.M., et al. Hum. Genet. 127(2):191-199(2010). Wang, W.H., et al. Audiol. Neurootol. 15(2):81-87(2010). Sargiannidou, I., et al. Neurobiol. Dis. 30(2):221-233(2008).

Other Notes

Small volumes of anti-GJC3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for GJC3 purchase

MBS6302330 is an antibody targeting GJC3. Also known as GJC3, CT (GJC3, GJE1, Gap junction gamma-3 protein, Connexin-30.2, Connexin-31.3, Gap junction epsilon-1 protein) (MaxLight 405). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for GJC3. It may not necessarily be applicable to this product.

NCBI GI #

31559821

NCBI GeneID

349149

NCBI Accession #

NP_853516.1

UniProt Primary Accession #

Q8NFK1

UniProt Secondary Accession #

Q86XI9; A4D296

UniProt Related Accession #

Q8NFK1

GenBank Nucleotide #

NM_181538.2

NCBI Official Full Name

gap junction gamma-3 protein

NCBI Official Synonym Full Names

gap junction protein, gamma 3, 30.2kDa

NCBI Official Symbol

GJC3

NCBI Official Synonym Symbols

CX29; GJE1; CX30.2; CX31.3

UniProt Protein Name

Gap junction gamma-3 protein

UniProt Synonym Protein Names

Connexin-30.2; Cx30.2; Connexin-31.3; Cx31.3; Gap junction epsilon-1 protein

Protein Family

Gap junction gamma-3 protein

UniProt Gene Name

GJC3

UniProt Synonym Gene Names

GJE1; Cx30.2; Cx31.3

UniProt Entry Name

CXG3_HUMAN

NCBI Protein Information

gap junction gamma-3 protein; connexin 29; connexin-30.2; connexin-31.3; gap junction epsilon-1 protein

UniProt Comments for GJC3

GJC3: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. Belongs to the connexin family. Gamma-type subfamily.

Protein type: Membrane protein, integral; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 7q22.1

Cellular Component: connexon complex; integral to membrane; myelin sheath

Molecular Function: protein homodimerization activity

Biological Process: myelination; sensory perception of sound; cell communication

Research Articles on GJC3

1. The connexin30.2/CX31.3 shares functional properties with pannexin (hemi) channels rather than gap junction channels of other Connexins.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-GJC3 antibody

Reference Product	PubMed Publications
GJB3 antibody	>2 publications with GJC3 and GJB3
GJB1 antibody	>1 publications with GJC3 and GJB1