• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

SLC2A2 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS626434

Glucose transporter 2 isoform is an integral plasma membrane glycoprotein of the liver, islet beta cells, intestine, and kidney epithelium. It mediates facilitated bidirectional glucose transport. Because of its low affinity for glucose, it has been suggested… More details

$895 / 0.2 mL +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
GLUT2 (Slc2a2), Polyclonal Antibody
Full Product Name
GLUT2, NT (Solute Carrier Family 2, Facilitated Glucose Transporter Member 2, Glucose Transporter Type 2, Liver, GLUT-2, SLC2A2)
Product Gene Name
anti-Slc2a2 antibody
Product Synonym Names
Anti -GLUT2, NT (Solute Carrier Family 2, Facilitated Glucose Transporter Member 2, Glucose Transporter Type 2, Liver, GLUT-2, SLC2A2)
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, 0.09% sodium azide.
Purity/Purification
Affinity Purified
Purified by Protein A affinity chromatography.
Specificity
Recognizes human SLC2A2.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
57,107 Da
Chromosome Location
Chromosome: 3; NC_000069.5 (28596825..28627283). Location: 3 A3; 3 14.4 cM
3D Structure
ModBase 3D Structure for P14246
Immunogen
Synthetic peptide selected from the N-terminal region of human SLC2A2 (KLH).

Product Categories/Family for anti-Slc2a2 antibody

Antibodies; Abs to Glucose Transporters
Applications Tested/Suitable for anti-Slc2a2 antibody
ELISA (EL/EIA), Western Blot (WB), Flow Cytometry (FC/FACS)
Application Notes for anti-Slc2a2 antibody
Suitable for use in ELISA, Western Blot, and Flow Cytometry.
Dilution: Western Blot: 1:50-1:100
ELISA: 1:1,000
Flow Cytometry: 1:10-1:50

Western Blot (WB) of anti-Slc2a2 antibody

Western blot analysis of SLC2A2 Antibody (N-term) in HepG2 cell line lysates (35ug/lane). SLC2A2 (arrow) was detected using the purified Pab.
Rabbit Anti-SLC2A2 Polyclonal Antibody – Cat# MBS626434

Flow Cytometry (FC/FACS) of anti-Slc2a2 antibody

Flow cytometric analysis of HL-60 cells using GLUT2 (SLC2A2) Antibody (N-term) (bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Rabbit Anti-SLC2A2 Polyclonal Antibody, Flow Cytometry (FC/FACS) – Cat# MBS626434

Other Notes

Small volumes of anti-Slc2a2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Slc2a2 purchase

MBS626434 is an antibody targeting Slc2a2. Also known as GLUT2, NT (Solute Carrier Family 2, Facilitated Glucose Transporter Member 2, Glucose Transporter Type 2, Liver, GLUT-2, SLC2A2). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for Slc2a2. It may not necessarily be applicable to this product.

NCBI GI #
683589
NCBI GeneID
20526
UniProt Primary Accession #
P14246
UniProt Secondary Accession #
Q3TNA5; Q9DBA7
UniProt Related Accession #
P14246
NCBI Official Full Name
GLUT2
NCBI Official Synonym Full Names
solute carrier family 2 (facilitated glucose transporter), member 2
NCBI Official Symbol
Slc2a2
NCBI Official Synonym Symbols
Glut2; Glut-2; AI266973
UniProt Protein Name
Solute carrier family 2, facilitated glucose transporter member 2
UniProt Synonym Protein Names
Glucose transporter type 2, liver
Protein Family
Solute carrier family
UniProt Gene Name
Slc2a2
UniProt Synonym Gene Names
Glut-2; Glut2
UniProt Entry Name
GTR2_MOUSE
NCBI Protein Information
solute carrier family 2, facilitated glucose transporter member 2; liver-type glucose transporter; glucose transporter type 2, liver

UniProt Comments for Slc2a2

GLUT2: an integral membrane facilitative glucose transporter. One of 13 members of the human equilibrative glucose transport protein family. Present at high levels in the plasma membrane of pancreatic b-cells where it initiates the first step in glucose-stimulated insulin secretion, a glucose metabolism-dependent signaling mechanism. May mediate the bidirectional transfer of glucose across the plasma membrane of hepatocytes. May also participate with the Na( +2)/glucose cotransporter in the transcellular transport of glucose in the small intestine and kidney. Required for glucose sensitivity in the hypothalamus and brain stem. Involved in the control of food intake and stimulation of glucose uptake by peripheral tissues.

Protein type: Membrane protein, integral; Membrane protein, multi-pass; Transporter, SLC family; Transporter

Cellular Component: membrane; brush border membrane; basolateral plasma membrane; cytoplasm; plasma membrane; integral to membrane; cytosol; endosome; brush border

Molecular Function: D-glucose transmembrane transporter activity; dehydroascorbic acid transporter activity; transporter activity; glucose transmembrane transporter activity; transmembrane transporter activity; substrate-specific transmembrane transporter activity; insulin receptor binding

Biological Process: carbohydrate utilization; transport; carbohydrate transport; glucose transport; transmembrane transport
Show more

Research Articles on Slc2a2

1. Our data provide evidence that glucose detection by GLUT2 contributes to the control of food intake by the hypothalamus

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-Slc2a2 antibody

 Products by Pathway  Pathway Diagram
 Carbohydrate Digestion And Absorption Pathway antibodies  Carbohydrate Digestion And Absorption Pathway Diagram
 Carbohydrate Digestion And Absorption Pathway antibodies  Carbohydrate Digestion And Absorption Pathway Diagram
 Facilitative Na+-independent Glucose Transporters Pathway antibodies  Facilitative Na+-independent Glucose Transporters Pathway Diagram
 Fatty Acid, Triacylglycerol, And Ketone Body Metabolism Pathway antibodies  Fatty Acid, Triacylglycerol, And Ketone Body Metabolism Pathway Diagram
 Glucose Transport Pathway antibodies  Glucose Transport Pathway Diagram
 Glycolysis And Gluconeogenesis Pathway antibodies  Glycolysis And Gluconeogenesis Pathway Diagram
 Hexose Transport Pathway antibodies  Hexose Transport Pathway Diagram
 Maturity Onset Diabetes Of The Young Pathway antibodies  Maturity Onset Diabetes Of The Young Pathway Diagram
 Maturity Onset Diabetes Of The Young Pathway antibodies  Maturity Onset Diabetes Of The Young Pathway Diagram
 Metabolism Of Carbohydrates Pathway antibodies  Metabolism Of Carbohydrates Pathway Diagram

Diseases associated with anti-Slc2a2 antibody

 Disease Name  Pubmed Publications
 Diabetes Mellitus Antibodies  >48 publications with Slc2a2 and Diabetes Mellitus
 Diabetes Mellitus, Type 2 Antibodies  >28 publications with Slc2a2 and Diabetes Mellitus, Type 2
 Hyperglycemia Antibodies  >25 publications with Slc2a2 and Hyperglycemia
 Insulin Resistance Antibodies  >22 publications with Slc2a2 and Insulin Resistance
 Glucose Intolerance Antibodies  >15 publications with Slc2a2 and Glucose Intolerance
 Neoplasms Antibodies  >14 publications with Slc2a2 and Neoplasms
 Diabetes Mellitus, Experimental Antibodies  >13 publications with Slc2a2 and Diabetes Mellitus, Experimental
 Obesity Antibodies  >13 publications with Slc2a2 and Obesity
 Hyperinsulinism Antibodies  >12 publications with Slc2a2 and Hyperinsulinism
 Drug Toxicity Antibodies  >9 publications with Slc2a2 and Drug Toxicity

Organs/Tissues associated with anti-Slc2a2 antibody

 Organ/Tissue Name  Pubmed Publications
 Pancreas Antibodies  >63 publications with Slc2a2 and Pancreas
 Liver Antibodies  >20 publications with Slc2a2 and Liver
 Kidney Antibodies  >11 publications with Slc2a2 and Kidney
 Embryonic Tissue Antibodies  >3 publications with Slc2a2 and Embryonic Tissue
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000