Rabbit Anti-GPAM Polyclonal Antibody – Cat# MBS9148552

Western blot analysis of lysates from Mouse liver using GPAM Rabbit pAb (MBS9148552) at 1:1000 dilution.
Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.
Lysates/proteins: 25 ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit (RM00020).
Exposure time: 5s.

GPAM Antibody – Rabbit Polyclonal

Name: GPAM Antibody; Polyclonal; Rabbit; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS9148552
Price: 225 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS9148552

This gene encodes a mitochondrial enzyme which prefers saturated fatty acids as its substrate for the synthesis of glycerolipids. This metabolic pathway's first step is catalyzed by the encoded enzyme. Two forms for this enzyme exist, one in the mitochondria… More details

$225 / 0.02 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

GPAM, Polyclonal Antibody

Full Product Name

GPAM Rabbit pAb

Product Gene Name

anti-GPAM antibody

Product Synonym Names

GPAM; GPAT; GPAT1; glycerol-3-phosphate acyltransferase; mitochondrial

Immunogen Sequence

GTISLPCQTF YQVCHETVGK FIQYGILTVA EHDDQEDISP SLAEQQWDKK LPEPLSWRSD EEDEDSDFGE EQRDCYLKVS QSKEHQQFIT FLQRLLGPLL E

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human

Form/Format

PBS with 0.05% proclin300, 50% glycerol, pH7.3.

Purity/Purification

Affinity purification

Preparation and Storage

Store at -20 degree C. Avoid freeze/thaw cycles.

Molecular Weight

Calculated MW: 93kDa
Observed MW: 90-93kDa

OMIM

602395

3D Structure

ModBase 3D Structure for Q9HCL2

Cross Reactivity

Mouse, Rat

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 630-730 of human GPAM(NP_065969.3).

Product Categories/Family for anti-GPAM antibody

Cancer; Signal Transduction; Endocrine & Metabolism; Mitochondrial metabolism; Mitochondrial markers; Lipid Metabolism; Cardiovascular; Lipids; Fatty Acids; Antibodies

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Applications Tested/Suitable for anti-GPAM antibody

Western Blot (WB), ELISA (EIA)

Application Notes for anti-GPAM antibody

WB: 1:500-1:1000
ELISA: Recommended starting concentration is 1ug/mL.
Please optimize the concentration based on your specific assay requirements.

Other Notes

Small volumes of anti-GPAM antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for GPAM purchase

MBS9148552 is an antibody targeting GPAM. Also known as GPAM Rabbit pAb. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for GPAM. It may not necessarily be applicable to this product.

NCBI GI #

190358539

NCBI GeneID

57678

NCBI Accession #

NP_065969

UniProt Primary Accession #

Q9HCL2

UniProt Secondary Accession #

Q5VW51; Q86TA3

UniProt Related Accession #

Q9HCL2

GenBank Nucleotide #

NM_020918.5

UniProt Protein Name

Glycerol-3-phosphate acyltransferase 1, mitochondrial

UniProt Gene Name

GPAM

UniProt Synonym Gene Names

GPAT1; KIAA1560; GPAT-1

UniProt Entry Name

GPAT1_HUMAN

UniProt Comments for GPAM

GPAM: glycerol-3-phosphate acyltransferase is an integral multi-pass enzyme of the mitochondrial outer membrane. It performs the first step in de novo phospholipid biosynthesis. Member of the phospholipid and glycerol acyltransferase family

Protein type: Lipid Metabolism - glycerolipid; Mitochondrial; Lipid Metabolism - glycerophospholipid; Membrane protein, multi-pass; Transferase; Membrane protein, integral; EC 2.3.1.15

Chromosomal Location of Human Ortholog: 10q25.2

Cellular Component: mitochondrial outer membrane; mitochondrial inner membrane; integral to membrane; plasma membrane

Molecular Function: glycerol-3-phosphate O-acyltransferase activity

Biological Process: regulation of cytokine secretion; acyl-CoA metabolic process; glycerophospholipid biosynthetic process; triacylglycerol biosynthetic process; cellular lipid metabolic process; positive regulation of multicellular organism growth; fatty acid metabolic process; positive regulation of activated T cell proliferation; fatty acid homeostasis; phospholipid metabolic process; response to glucose stimulus; phosphatidic acid biosynthetic process; CDP-diacylglycerol biosynthetic process; defense response to virus; phospholipid homeostasis

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-GPAM antibody

Reference Product	PubMed Publications
AGPAT3 antibody	>2 publications with GPAM and AGPAT3
GPD1 antibody	>1 publications with GPAM and GPD1
AGPAT4 antibody	>1 publications with GPAM and AGPAT4
AGPAT6 antibody	>1 publications with GPAM and AGPAT6

Pathways associated with anti-GPAM antibody

Products by Pathway	Pathway Diagram
Activation Of Gene Expression By SREBF (SREBP) Pathway antibodies	Activation Of Gene Expression By SREBF (SREBP) Pathway Diagram
CDP-diacylglycerol Biosynthesis Pathway antibodies	CDP-diacylglycerol Biosynthesis Pathway Diagram
Fatty Acid, Triacylglycerol, And Ketone Body Metabolism Pathway antibodies	Fatty Acid, Triacylglycerol, And Ketone Body Metabolism Pathway Diagram
Glycerolipid Metabolism Pathway antibodies	Glycerolipid Metabolism Pathway Diagram
Glycerolipid Metabolism Pathway antibodies	Glycerolipid Metabolism Pathway Diagram
Glycerophospholipid Biosynthesis Pathway antibodies	Glycerophospholipid Biosynthesis Pathway Diagram
Glycerophospholipid Metabolism Pathway antibodies	Glycerophospholipid Metabolism Pathway Diagram
Glycerophospholipid Metabolism Pathway antibodies	Glycerophospholipid Metabolism Pathway Diagram
Metabolic Pathways antibodies	Metabolic Pathways Diagram
Metabolism Pathway antibodies	Metabolism Pathway Diagram

Diseases associated with anti-GPAM antibody

Disease Name	Pubmed Publications
Fatty Liver Antibodies	>9 publications with GPAM and Fatty Liver
Inflammation Antibodies	>8 publications with GPAM and Inflammation
Liver Diseases Antibodies	>5 publications with GPAM and Liver Diseases
Dyslipidemias Antibodies	>3 publications with GPAM and Dyslipidemias
Insulin Resistance Antibodies	>3 publications with GPAM and Insulin Resistance
Cardiovascular Diseases Antibodies	>2 publications with GPAM and Cardiovascular Diseases
Atherosclerosis Antibodies	>2 publications with GPAM and Atherosclerosis
Hypertriglyceridemia Antibodies	>2 publications with GPAM and Hypertriglyceridemia
Hyperlipidemias Antibodies	>2 publications with GPAM and Hyperlipidemias
Kidney Diseases Antibodies	>1 publications with GPAM and Kidney Diseases

Organs/Tissues associated with anti-GPAM antibody

Organ/Tissue Name	Pubmed Publications
Liver Antibodies	>18 publications with GPAM and Liver
Blood Antibodies	>15 publications with GPAM and Blood
Adipose Tissue Antibodies	>12 publications with GPAM and Adipose Tissue
Lung Antibodies	>6 publications with GPAM and Lung
Muscle Antibodies	>4 publications with GPAM and Muscle
Mammary Gland Antibodies	>4 publications with GPAM and Mammary Gland
Heart Antibodies	>2 publications with GPAM and Heart
Thyroid Antibodies	>2 publications with GPAM and Thyroid
Placenta Antibodies	>1 publications with GPAM and Placenta
Embryonic Tissue Antibodies	>1 publications with GPAM and Embryonic Tissue