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GPIP137 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6478740

MBS6478740 is an antibody targeting GPIP137. Also known as GPIP137, CT (Caprin-1, Cytoplasmic Activation-and Proliferation-associated Protein 1, GPI-anchored Membrane Protein 1, GPI-anchored Protein p137, p137GPI, Cell Cycle-associated Protein 1, Membrane… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
GPIP137, Polyclonal Antibody
Full Product Name
GPIP137, CT (Caprin-1, Cytoplasmic Activation-and Proliferation-associated Protein 1, GPI-anchored Membrane Protein 1, GPI-anchored Protein p137, p137GPI, Cell Cycle-associated Protein 1, Membrane Component Chromosome 11 Surface Marker 1, CAPRIN1, GPIAP1
Product Gene Name
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Fluorescein Isothiocyanate (FITC).
Purity/Purification
Purified by Protein G Affinity Chromatography.
Specificity
Recognizes human GPIP137.
Preparation and Storage
Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: FITC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
76,862 Da
OMIM
601178
3D Structure
ModBase 3D Structure for Q14444
Immunogen
Synthetic peptide selected from the C-terminjal region of human GPIP137 (KLH).
Conjugate
FITC
Note
Preservative Free
Special Handling
Light sensitive

Product Categories/Family for anti-GPIP137 antibody

Applications Tested/Suitable for anti-GPIP137 antibody
Immunohistochemistry (IHC), FLISA, Western Blot (WB)
Application Notes for anti-GPIP137 antibody
IHC: 1:50-1:100
FLISA: 1:1,000
WB: 1:100-1:500
Applications are based on unconjugated antibody.

Western Blot (WB) of anti-GPIP137 antibody

The anti-GPIP137 Pab is used in Western blot to detect GPIP137 in HL-60 cell lysate.
Rabbit Anti-GPIP137 Polyclonal Antibody – Cat# MBS6478740

Immunohistochemistry (IHC) of anti-GPIP137 antibody

Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
Rabbit Anti-GPIP137 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS6478740

Product References and Citations for anti-GPIP137 antibody

1. Gessler, M., et al., Genomics 32(1):169-170 (1996). 2. Ellis, J.A., et al., J. Biol. Chem. 270(35):20717-20723 (1995).

Other Notes

Small volumes of anti-GPIP137 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for GPIP137. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
caprin-1 isoform 2
NCBI Official Synonym Full Names
cell cycle associated protein 1
NCBI Official Symbol
CAPRIN1
NCBI Official Synonym Symbols
M11S1; GPIAP1; RNG105; GPIP137; GRIP137; p137GPI
UniProt Protein Name
Caprin-1
UniProt Synonym Protein Names
Cell cycle-associated protein 1; Cytoplasmic activation- and proliferation-associated protein 1; GPI-anchored membrane protein 1; GPI-anchored protein p137; GPI-p137; p137GPI; Membrane component chromosome 11 surface marker 1; RNA granule protein 105
UniProt Gene Name
CAPRIN1
UniProt Synonym Gene Names
GPIAP1; GPIP137; M11S1; RNG105; GPI-p137; p137GPI
UniProt Entry Name
CAPR1_HUMAN
NCBI Protein Information
caprin-1

UniProt Comments for GPIP137

CAPRIN1: May regulate the transport and translation of mRNAs of proteins involved in synaptic plasticity in neurons and cell proliferation and migration in multiple cell types. Belongs to the caprin family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: RNA-binding; Cell surface

Chromosomal Location of Human Ortholog: 11p13

Cellular Component: membrane; stress granule; integral to plasma membrane; cytoplasm; dendrite; cytosol

Molecular Function: RNA binding

Biological Process: negative regulation of translation; positive regulation of dendrite morphogenesis
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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