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GRO gamma Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS535928

MBS535928 is an antibody targeting GRO gamma. Also known as GRO gamma antibody. Reactive in Human GRO-gamma. Host: Rabbit. Affinity purified Rabbit polyclonal GRO gamma antibody More details

$685 / 0.05 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
GRO gamma, Polyclonal Antibody
Full Product Name
GRO gamma antibody
Product Gene Name
anti-GRO gamma antibody
Product Synonym Names
Polyclonal GRO gamma; Anti-GRO gamma; MIP-2; MGSA gamma; Growth Regulated/Melanoma Growth Stimulatory Activity; GRO3; CXCL3
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human GRO-gamma
Form/Format
Lyophilized from PBS, pH 7.2.
Specificity
Human GRO-gamma
Preparation and Storage
Store at -20 degree C until reconstitution. Following reconstitution product may be stored at 4 degree C in the short term. For long term storage aliquot and freeze at -20 degree C. Avoid repeated freeze/thaw cycles.
Molecular Weight
7.9 kDa (predicted detection band MW)
OMIM
139111
Immunogen
GRO gamma antibody was raised in rabbit using highly pure recombinant hGRO-gamma as the immunogen.

Product Categories/Family for anti-GRO gamma antibody

Cytokines & Growth Factors; Purified Polyclonal Antibodies
Applications Tested/Suitable for anti-GRO gamma antibody
ELISA (EIA), Inhibition, Western Blot (WB)
Application Notes for anti-GRO gamma antibody
ELISA: 0.5-2 ug/ml
Inhibition: 1-2 ug/ml
WB: 0.1-0.2 ug/ml

Other Notes

Small volumes of anti-GRO gamma antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for GRO gamma. It may not necessarily be applicable to this product.

NCBI GI #
30023531
NCBI GeneID
2921
NCBI Accession #
AAP13105.1
UniProt Secondary Accession #
Q4W5H9
UniProt Related Accession #
P19876
NCBI Official Full Name
GRO-gamma, partial
NCBI Official Synonym Full Names
chemokine (C-X-C motif) ligand 3
NCBI Official Symbol
CXCL3
NCBI Official Synonym Symbols
GRO3; GROg; MIP2B; SCYB3; MIP-2b; CINC-2b
UniProt Protein Name
C-X-C motif chemokine 3
UniProt Synonym Protein Names
GRO-gamma(1-73); Growth-regulated protein gamma; GRO-gamma
Protein Family
Growth-regulated protein
UniProt Gene Name
CXCL3
UniProt Synonym Gene Names
GRO3; GROG; SCYB3; GRO-gamma; MIP2-beta
UniProt Entry Name
CXCL3_HUMAN
NCBI Protein Information
C-X-C motif chemokine 3

NCBI Summary for GRO gamma

This antimicrobial gene encodes a member of the CXC subfamily of chemokines. The encoded protein is a secreted growth factor that signals through the G-protein coupled receptor, CXC receptor 2. This protein plays a role in inflammation and as a chemoattractant for neutrophils. [provided by RefSeq, Sep 2014]
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UniProt Comments for GRO gamma

CXCL3: Ligand for CXCR2. Has chemotactic activity for neutrophils. May play a role in inflammation and exert its effects on endothelial cells in an autocrine fashion. In vitro, the processed form GRO-gamma(5-73) shows a fivefold higher chemotactic activity for neutrophilic granulocytes. Belongs to the intercrine alpha (chemokine CxC) family.

Protein type: Secreted, signal peptide; Motility/polarity/chemotaxis; Secreted

Chromosomal Location of Human Ortholog: 4q21

Cellular Component: extracellular space; extracellular region

Molecular Function: chemokine activity; CXCR chemokine receptor binding

Biological Process: neutrophil chemotaxis; G-protein coupled receptor protein signaling pathway; positive regulation of leukocyte chemotaxis; immune response; response to lipopolysaccharide; inflammatory response; regulation of cell proliferation
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Research Articles on GRO gamma

1. results support a functional role of CXCL3 in breast cancer metastasis and as a viable target for cancer therapy

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-GRO gamma antibody

 Reference Product  PubMed Publications
 CCL20 antibody  >41 publications with GRO gamma and CCL20
 CCL5 antibody  >26 publications with GRO gamma and CCL5
 CXCL10 antibody  >21 publications with GRO gamma and CXCL10
 CXCL11 antibody  >13 publications with GRO gamma and CXCL11
 CXCR2 antibody  >12 publications with GRO gamma and CXCR2
 CXCR1 antibody  >9 publications with GRO gamma and CXCR1
 CXCL12 antibody  >8 publications with GRO gamma and CXCL12
 CXCL16 antibody  >6 publications with GRO gamma and CXCL16
 CCL19 antibody  >6 publications with GRO gamma and CCL19
 CCR1 antibody  >3 publications with GRO gamma and CCR1

Pathways associated with anti-GRO gamma antibody

 Products by Pathway  Pathway Diagram
 Chemokine Receptors Bind Chemokines Pathway antibodies  Chemokine Receptors Bind Chemokines Pathway Diagram
 Chemokine Signaling Pathway antibodies  Chemokine Signaling Pathway Diagram
 Chemokine Signaling Pathway antibodies  Chemokine Signaling Pathway Diagram
 Class A/1 (Rhodopsin-like Receptors) Pathway antibodies  Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 G Alpha (i) Signalling Events Pathway antibodies  G Alpha (i) Signalling Events Pathway Diagram
 GPCR Downstream Signaling Pathway antibodies  GPCR Downstream Signaling Pathway Diagram
 GPCR Ligand Binding Pathway antibodies  GPCR Ligand Binding Pathway Diagram
 Legionellosis Pathway antibodies  Legionellosis Pathway Diagram

Diseases associated with anti-GRO gamma antibody

 Disease Name  Pubmed Publications
 Inflammation Antibodies  >75 publications with GRO gamma and Inflammation
 Necrosis Antibodies  >36 publications with GRO gamma and Necrosis
 Respiratory Tract Diseases Antibodies  >13 publications with GRO gamma and Respiratory Tract Diseases
 Lung Diseases Antibodies  >13 publications with GRO gamma and Lung Diseases
 Immune System Diseases Antibodies  >11 publications with GRO gamma and Immune System Diseases
 Skin Diseases Antibodies  >9 publications with GRO gamma and Skin Diseases
 Death Antibodies  >7 publications with GRO gamma and Death
 Fibrosis Antibodies  >6 publications with GRO gamma and Fibrosis
 Neoplasms, Experimental Antibodies  >5 publications with GRO gamma and Neoplasms, Experimental
 Lung Neoplasms Antibodies  >4 publications with GRO gamma and Lung Neoplasms

Organs/Tissues associated with anti-GRO gamma antibody

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >65 publications with GRO gamma and Blood
 Lung Antibodies  >19 publications with GRO gamma and Lung
 Intestine Antibodies  >13 publications with GRO gamma and Intestine
 Brain Antibodies  >8 publications with GRO gamma and Brain
 Embryonic Tissue Antibodies  >4 publications with GRO gamma and Embryonic Tissue
 Liver Antibodies  >4 publications with GRO gamma and Liver
 Uterus Antibodies  >2 publications with GRO gamma and Uterus
 Pancreas Antibodies  >1 publications with GRO gamma and Pancreas
 Bladder Antibodies  >1 publications with GRO gamma and Bladder
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