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GSDMB Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS7002778

May play a role as secretory or metabolic product involved in secretory pathway. May also play a role in achieving and maintaining the final differentiation state of epithelial cells. More details

$230 / 0.05 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
GSDMB, Polyclonal Antibody
Full Product Name
GSDMB Antibody
Product Gene Name
Product Synonym Names
Gasdermin-B (Gasdermin-like protein), GSDMB, GSDML
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Liquid
Purity/Purification
>95%, Protein G purified
Preparation and Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Matching Pairs
Unconjugated Antibody: GSDMB (MBS7002778)
Biotin Conjugated Antibody: GSDMB (MBS1493406)
Matching Pairs
Unconjugated Antibody: GSDMB (MBS7002778)
HRP Conjugated Antibody: GSDMB (MBS1496419)
OMIM
611221
3D Structure
ModBase 3D Structure for Q8TAX9
Immunogen
Recombinant Human Gasdermin-B protein (63-310AA)
Conjugation
Non-conjugated
Storage Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Species
Human
Research Area
Cell Biology
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-GSDMB antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-GSDMB antibody
Recommended dilution: WB:1:500-2000, IHC:1:20-1:200

Western Blot (WB) of anti-GSDMB antibody

Western blot
All lanes: GSDMB antibody at 8ug/ml+ Colo320 whole cell lysate
Goat polyclonal to rabbit at 1/10000 dilution
Predicted band size: 47,46,48,19 kDa
Observed band size: 47 kDa
Rabbit Anti-GSDMB Polyclonal Antibody – Cat# MBS7002778

Immunohistochemistry (IHC) of anti-GSDMB antibody

Immunohistochemistry of paraffin-embedded human colon cancer using MBS7002778 at dilution of 1:100
Rabbit Anti-GSDMB Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS7002778

Other Notes

Small volumes of anti-GSDMB antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for GSDMB purchase

MBS7002778 is an antibody targeting GSDMB. Also known as GSDMB Antibody. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for GSDMB. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
gasdermin-B isoform 1
NCBI Official Synonym Full Names
gasdermin B
NCBI Official Symbol
GSDMB
NCBI Official Synonym Symbols
GSDML; PP4052; PRO2521
UniProt Protein Name
Gasdermin-B
UniProt Synonym Protein Names
Gasdermin-like protein
Protein Family
UniProt Gene Name
GSDMB
UniProt Synonym Gene Names
GSDML
UniProt Entry Name
GSDMB_HUMAN
NCBI Protein Information
gasdermin-B

NCBI Summary for GSDMB

This gene encodes a member of the gasdermin-domain containing protein family. Other gasdermin-family genes are implicated in the regulation of apoptosis in epithelial cells, and are linked to cancer. Multiple transcript variants encoding different isoforms have been found for this gene. Additional variants have been described, but they are candidates for nonsense-mediated mRNA decay (NMD) and are unlikely to be protein-coding. [provided by RefSeq, Sep 2009]
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UniProt Comments for GSDMB

GSDML: May play a role as secretory or metabolic product involved in secretory pathway. May also play a role in achieving and maintaining the final differentiation state of epithelial cells. Belongs to the gasdermin family. 6 isoforms of the human protein are produced by alternative splicing.

Chromosomal Location of Human Ortholog: 17q12

Cellular Component: cytoplasm
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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