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GTF2IRD2B Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS9203815

This gene encodes a glycosylated phosphoprotein with aleucine zipper motif, two helix-loop-helix motifs (I repeats) thatare similar to domains found in the TFII-I family of transcriptionfactors, one CHARLIE8 transposable element-like sequence, and a BEDzinc… More details

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Product Overview

Online Datasheet in PDF
Product Name
GTF2IRD2B, Polyclonal Antibody
Full Product Name
GTF2IRD2B Antibody (C-term)
Product Gene Name
Product Synonym Names
General transcription factor II-I repeat domain-containing protein 2B; GTF2I repeat domain-containing protein 2B; Transcription factor GTF2IRD2-beta; GTF2IRD2B
Clonality
Polyclonal
Isotype
Rabbit Ig
Host
Rabbit
Species Reactivity
Human
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Concentration
Vial Concentration: 0.37 (lot specific)
Specificity
This GTF2IRD2B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 467-494 amino acids from the C-terminal region of human GTF2IRD2B.
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Antibody/Peptide Pairs
Molecular Weight
107233
Immunogen Sequence Positions
467-494
OMIM
608900
3D Structure
ModBase 3D Structure for Q6EKJ0
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN
Applications Tested/Suitable for anti-GTF2IRD2B antibody
Western Blot (WB), ELISA (EIA)
Application Notes for anti-GTF2IRD2B antibody
WB~~1:1000

Western Blot (WB) of anti-GTF2IRD2B antibody

GTF2IRD2B Antibody (C-term) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the GTF2IRD2B antibody detected the GTF2IRD2B protein (arrow).
Rabbit Anti-GTF2IRD2B Polyclonal Antibody – Cat# MBS9203815

Product References and Citations for anti-GTF2IRD2B antibody

Hinsley, T.A., et al. Protein Sci. 13(10):2588-2599(2004)
Tipney, H.J., et al. Eur. J. Hum. Genet. 12(7):551-560(2004)

Other Notes

Small volumes of anti-GTF2IRD2B antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for GTF2IRD2B purchase

MBS9203815 is an antibody targeting GTF2IRD2B. Also known as GTF2IRD2B Antibody (C-term). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for GTF2IRD2B. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
general transcription factor II-I repeat domain-containing protein 2B
NCBI Official Synonym Full Names
GTF2I repeat domain containing 2B
NCBI Official Symbol
GTF2IRD2B
UniProt Protein Name
General transcription factor II-I repeat domain-containing protein 2B
UniProt Synonym Protein Names
Transcription factor GTF2IRD2-beta
UniProt Gene Name
GTF2IRD2B
UniProt Synonym Gene Names
GTF2I repeat domain-containing protein 2B
UniProt Entry Name
GTD2B_HUMAN
NCBI Protein Information
general transcription factor II-I repeat domain-containing protein 2B

NCBI Summary for GTF2IRD2B

This gene encodes a glycosylated phosphoprotein with a leucine zipper motif, two helix-loop-helix motifs (I repeats) that are similar to domains found in the TFII-I family of transcription factors, one CHARLIE8 transposable element-like sequence, and a BED zinc finger. This gene lies within a region that is deleted in Williams-Beuren syndrome. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. [provided by RefSeq, Jul 2008]
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UniProt Comments for GTF2IRD2B

GTF2IRD2B: GTF2IRD2B is located in the Williams-Beuren syndrome (WBS) critical region. WBS results from a hemizygous deletion of several genes on chromosome 7q11.23, thought to arise as a consequence of unequal crossing over between highly homologous low-copy repeat sequences flanking the deleted region. Belongs to the TFII-I family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: DNA-binding

Chromosomal Location of Human Ortholog: 7q11.23

Cellular Component: nucleus

Molecular Function: DNA binding

Biological Process: transcription, DNA-dependent; regulation of transcription, DNA-dependent
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Organs/Tissues associated with anti-GTF2IRD2B antibody

 Organ/Tissue Name  Pubmed Publications
 Muscle Antibodies  >1 publications with GTF2IRD2B and Muscle
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