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GUCY2D Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS7109843

Probably plays a specific functional role in the rods and/or cones of photoreceptors. It may be the enzyme involved in the resynthesis of cGMP required for recovery of the dark state after phototransduction. More details

$230 / 0.05 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
GUCY2D, Polyclonal Antibody
Full Product Name
GUCY2D Antibody
Product Gene Name
Product Synonym Names
Retinal guanylyl cyclase 1; RETGC-1; EC 4.6.1.2; Guanylate cyclase 2D; retinal; Rod outer segment membrane guanylate cyclase; ROS-GC; GUCY2D; CORD6; GUC1A4; GUC2D; RETGC; RETGC1
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Liquid
Purity/Purification
>95%, Protein G purified
Preparation and Storage
Upon receipt, store at -20 degree C or -80 degree C. Avoid repeated freeze.
Matching Pairs
Unconjugated Antibody: GUCY2D (MBS7109843)
HRP Conjugated Antibody: GUCY2D (MBS7109844)
Matching Pairs
Unconjugated Antibody: GUCY2D (MBS7109843)
FITC Conjugated Antibody: GUCY2D (MBS7109845)
OMIM
M92432 mRNA
3D Structure
ModBase 3D Structure for Q02846
Immunogen
Recombinant Human Retinal guanylyl cyclase 1 protein (362-462AA)
Immunogen Species
Homo sapiens (Human)
Research Area
Others
Target Names
GUCY2D
Conjugation
Non-conjugated
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-GUCY2D antibody
ELISA (EIA), Western Blot (WB), Immunofluorescence (IF)
Application Notes for anti-GUCY2D antibody
WB: 1:500-1:5000, IF: 1:200-1:500

Western Blot (WB) of anti-GUCY2D antibody

Western Blot
Positive WB detected in: U251 whole cell lysate
All lanes: GUCY2D antibody at 5.4ug/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 121 kDa
Observed band size: 121 kDa
Rabbit Anti-GUCY2D Polyclonal Antibody – Cat# MBS7109843

Immunofluorescence (IF) of anti-GUCY2D antibody

Immunofluorescence staining of HepG2 cells with MBS7109843 at 1:266, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4 degree C.The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG (H+L).
Rabbit Anti-GUCY2D Polyclonal Antibody, Immunofluorescence (IF) – Cat# MBS7109843

Other Notes

Small volumes of anti-GUCY2D antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for GUCY2D purchase

MBS7109843 is an antibody targeting GUCY2D. Also known as GUCY2D Antibody. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for GUCY2D. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
retinal guanylyl cyclase 1
NCBI Official Synonym Full Names
guanylate cyclase 2D, retinal
NCBI Official Symbol
GUCY2D
NCBI Official Synonym Symbols
LCA; CYGD; LCA1; RCD2; CACD1; CORD5; CORD6; GUC2D; ROSGC; retGC; GUC1A4; RETGC-1; ROS-GC1
UniProt Protein Name
Retinal guanylyl cyclase 1
UniProt Synonym Protein Names
Guanylate cyclase 2D, retinal; Rod outer segment membrane guanylate cyclase; ROS-GC
UniProt Gene Name
GUCY2D
UniProt Synonym Gene Names
CORD6; GUC1A4; GUC2D; RETGC; RETGC1; RETGC-1; ROS-GC
NCBI Protein Information
retinal guanylyl cyclase 1

NCBI Summary for GUCY2D

This gene encodes a retina-specific guanylate cyclase, which is a member of the membrane guanylyl cyclase family. Like other membrane guanylyl cyclases, this enzyme has a hydrophobic amino-terminal signal sequence followed by a large extracellular domain, a single membrane spanning domain, a kinase homology domain, and a guanylyl cyclase catalytic domain. In contrast to other membrane guanylyl cyclases, this enzyme is not activated by natriuretic peptides. Mutations in this gene result in Leber congenital amaurosis and cone-rod dystrophy-6 diseases. [provided by RefSeq, Dec 2008]
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-GUCY2D antibody

Organs/Tissues associated with anti-GUCY2D antibody

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