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HBE1v Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6305599

MaxLight550 is a new Yellow-Green photostable dye conjugate comparable to Alexa Fluor546, 555, DyLight549, Cy3, TRITC and offers better labeling efficiency, brighter imaging and increased immunodetection. Absorbance (550nm); Emission (575nm); Extinction… More details

$1060 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
HBE1v, Polyclonal Antibody
Full Product Name
HBE1v (HBE1, HBE, Hemoglobin subunit epsilon, Epsilon-globin, Hemoglobin epsilon chain) (MaxLight 550)
Product Gene Name
anti-HBE1v antibody
Product Synonym Gene Name
HBE1
Product Synonym Names
HBE1; HBE; Hemoglobin subunit epsilon; Epsilon-globin; Hemoglobin epsilon chain
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight550.
Purity/Purification
Purified by Protein A Affinity Chromatography.
Specificity
Recognizes human HBE1v.
Preparation and Storage
Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: MaxLight550 conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molecular Weight
16,203 Da
OMIM
142100
3D Structure
ModBase 3D Structure for P02100
Immunogen
KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 55-83 in the central region of human HBE1v, UniProt Accession #NP_005321.1; P02100.
Conjugate
MaxLight550
Note
Preservative Free

Product Categories/Family for anti-HBE1v antibody

Antibodies; Hemoglobin
Applications Tested/Suitable for anti-HBE1v antibody
Western Blot (WB), FLISA
Application Notes for anti-HBE1v antibody
WB: 1:100-500
FLISA: 1:1,000
Applications are based on unconjugated antibody.

Western Blot (WB) of anti-HBE1v antibody

Western Blot analysis in K562 cell line lysates (35ug/lane) usingMBS6000316. This demonstrates that MBS6000316 detected the HBE1 protein (arrow).
Rabbit Anti-HBE1v Polyclonal Antibody – Cat# MBS6305599

Product References and Citations for anti-HBE1v antibody

1. Nuinoon, M., et al. Hum. Genet. (2009). In press 2. Tachavanich, K., et al. Southeast Asian J. Trop. Med. Public Health 40(2):306-316(2009). 3. Naka, I., et al. Biochem. Genet. 46 (11-12), 708-711 (2008). 4. Winichagoon, P., et al. Transl Res 152(4):178-184(2008). 5. Das, B., et al. Ann. Hum. Biol. 35(4):422-431(2008).

Other Notes

Small volumes of anti-HBE1v antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for HBE1v purchase

MBS6305599 is an antibody targeting HBE1v. Also known as HBE1v (HBE1, HBE, Hemoglobin subunit epsilon, Epsilon-globin, Hemoglobin epsilon chain) (MaxLight 550). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for HBE1v. It may not necessarily be applicable to this product.

NCBI GI #
4885393
NCBI GeneID
3046
NCBI Accession #
NP_005321.1
UniProt Primary Accession #
P02100
UniProt Secondary Accession #
Q6FH44
UniProt Related Accession #
P02100
GenBank Nucleotide #
NM_005330.3
NCBI Official Full Name
hemoglobin subunit epsilon
NCBI Official Synonym Full Names
hemoglobin, epsilon 1
NCBI Official Symbol
HBE1
NCBI Official Synonym Symbols
HBE
UniProt Protein Name
Hemoglobin subunit epsilon
UniProt Synonym Protein Names
Epsilon-globin; Hemoglobin epsilon chain
UniProt Gene Name
HBE1
UniProt Synonym Gene Names
HBE
UniProt Entry Name
HBE_HUMAN
NCBI Protein Information
hemoglobin subunit epsilon

NCBI Summary for HBE1v

The epsilon globin gene (HBE) is normally expressed in the embryonic yolk sac: two epsilon chains together with two zeta chains (an alpha-like globin) constitute the embryonic hemoglobin Hb Gower I; two epsilon chains together with two alpha chains form the embryonic Hb Gower II. Both of these embryonic hemoglobins are normally supplanted by fetal, and later, adult hemoglobin. The five beta-like globin genes are found within a 45 kb cluster on chromosome 11 in the following order: 5'-epsilon - G-gamma - A-gamma - delta - beta-3' [provided by RefSeq, Jul 2008]
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UniProt Comments for HBE1v

HBE1: The epsilon chain is a beta-type chain of early mammalian embryonic hemoglobin. Belongs to the globin family.

Protein type: Carrier

Chromosomal Location of Human Ortholog: 11p15.5

Cellular Component: hemoglobin complex; cytosol

Molecular Function: iron ion binding; heme binding; hemoglobin alpha binding; oxygen binding; oxygen transporter activity

Biological Process: oxygen transport; protein heterooligomerization; negative regulation of transcription from RNA polymerase II promoter; blood coagulation
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Research Articles on HBE1v

1. Data indicate that Myb and BCL11A cooperate with DNMT1 to achieve developmental repression of embryonic and fetal beta-like human transgenic globin genes in the adult erythroid environment.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-HBE1v antibody

 Reference Product  PubMed Publications
 HBD antibody  >3 publications with HBE1v and HBD
 HBA1 antibody  >1 publications with HBE1v and HBA1
 MAFG antibody  >1 publications with HBE1v and MAFG
 MAFK antibody  >1 publications with HBE1v and MAFK
 HBZ antibody  >1 publications with HBE1v and HBZ
 HBA2 antibody  >1 publications with HBE1v and HBA2

Pathways associated with anti-HBE1v antibody

 Products by Pathway  Pathway Diagram
 Factors Involved In Megakaryocyte Development And Platelet Production Pathway antibodies  Factors Involved In Megakaryocyte Development And Platelet Production Pathway Diagram
 Hemostasis Pathway antibodies  Hemostasis Pathway Diagram

Diseases associated with anti-HBE1v antibody

 Disease Name  Pubmed Publications
 Carcinoma Antibodies  >5 publications with HBE1v and Carcinoma
 Inflammation Antibodies  >4 publications with HBE1v and Inflammation
 Liver Diseases Antibodies  >2 publications with HBE1v and Liver Diseases
 Necrosis Antibodies  >2 publications with HBE1v and Necrosis
 Intestinal Neoplasms Antibodies  >1 publications with HBE1v and Intestinal Neoplasms
 Brain Diseases Antibodies  >1 publications with HBE1v and Brain Diseases
 Leukemia, Myeloid Antibodies  >1 publications with HBE1v and Leukemia, Myeloid
 Hyperplasia Antibodies  >1 publications with HBE1v and Hyperplasia
 Carcinoma, Squamous Cell Antibodies  >1 publications with HBE1v and Carcinoma, Squamous Cell

Organs/Tissues associated with anti-HBE1v antibody

 Organ/Tissue Name  Pubmed Publications
 Lung Antibodies  >31 publications with HBE1v and Lung
 Blood Antibodies  >3 publications with HBE1v and Blood
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