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HIST1H4A Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS7109708

Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA… More details

$235 / 0.05 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
HIST1H4A, Polyclonal Antibody
Full Product Name
Propionyl-HIST1H4A (K16) Antibody
Product Gene Name
Product Synonym Names
Histone H4; HIST1H4A; H4/A; H4FA; AND; HIST1H4B; H4/I; H4FI; AND; HIST1H4C; H4/G; H4FG; AND; HIST1H4D; H4/B; H4FB; AND; HIST1H4E; H4/J; H4FJ; AND; HIST1H4F; H4/C; H4FC; AND; HIST1H4H; H4/H; H4FH; AND; HIST1H4I; H4/M; H4FM; AND; HIST1H4J; H4/E; H4FE; AND; HIST1H4K; H4/D; H4FD; AND; HIST1H4L; H4/K; H4FK; AND; HIST2H4A; H4/N; H4F2; H4FN; HIST2H4; AND; HIST2H4B; H4/O; H4FO; AND; HIST4H4
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Liquid
Purity/Purification
Antigen Affinity Purified
Preparation and Storage
Upon receipt, store at -20 degree C or -80 degree C. Avoid repeated freeze.
Molecular Weight
11,367 Da
OMIM
X00038 Genomic DNA
3D Structure
ModBase 3D Structure for P62805
Immunogen
Peptide sequence around site of propionyl-Lys(16) derived from human Histone H4
Conjugation
Non-conjugated
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-HIST1H4A antibody
ELISA (EIA), Western Blot (WB)
Application Notes for anti-HIST1H4A antibody
WB: 1:500-1:5000

Western Blot (WB) of anti-HIST1H4A antibody

Western Blot
Positive WB detected in: Hela whole cell lysate, A549 whole cell lysate, 293 whole cell lysate, K562 whole cell lysate, HepG2 whole cell lysate(treated with 10mM sodium propionate for 4h)
All lanes: HIST1H4A antibody at 0.95ug/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 12 KDa
Observed band size: 12 KDa
Rabbit Anti-HIST1H4A Polyclonal Antibody – Cat# MBS7109708

Other Notes

Small volumes of anti-HIST1H4A antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for HIST1H4A purchase

MBS7109708 is an antibody targeting HIST1H4A. Also known as Propionyl-HIST1H4A (K16) Antibody. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for HIST1H4A. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
histone H4
NCBI Official Synonym Full Names
histone cluster 2 H4 family member b
NCBI Official Symbol
HIST2H4B
NCBI Official Synonym Symbols
H4/o
UniProt Protein Name
Histone H4
UniProt Gene Name
HIST1H4A
UniProt Synonym Gene Names
H4/A; H4FA
NCBI Protein Information
histone H4

NCBI Summary for HIST1H4A

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H4 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in a histone cluster on chromosome 1. This gene is one of four histone genes in the cluster that are duplicated; this record represents the telomeric copy. [provided by RefSeq, Aug 2015]
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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