Rabbit Anti-HOXB9 Polyclonal Antibody – Cat# MBS6307939

HOXB9 Antibody (Center) western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the HOXB9 antibody detected the HOXB9 protein (arrow).

HOXB9 Antibody – Rabbit Polyclonal

Name: HOXB9 Antibody; Polyclonal; Rabbit; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS6307939
Price: 1060 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6307939

HOXB9 is a member of the Abd-B homeobox family and encodes a protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded nuclear protein functions as a sequence-specific transcription… More details

$1060 / 0.2 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

HOXB9, Polyclonal Antibody

Full Product Name

HOXB9, ID (HOXB9, HOX2E, Homeobox protein Hox-B9, Homeobox protein Hox-2.5, Homeobox protein Hox-2E) (Azide free) (HRP)

Product Gene Name

anti-HOXB9 antibody

Product Synonym Names

HOXB9; HOX2E; Homeobox protein Hox-B9; Homeobox protein Hox-2.5; Homeobox protein Hox-2E

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human

Form/Format

Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Horseradish Peroxidase (HRP).

Purity/Purification

Purified by Protein A Affinity Chromatography.

Preparation and Storage

Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Note: Sodium azide is a potent inhibitor of peroxidase and should not be added to HRP conjugates. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Molecular Weight

28,059 Da

Chromosome Location

Chromosome: 17; NC_000017.10 (46698518..46703835, complement). Location: 17q21.3

OMIM

142964

3D Structure

ModBase 3D Structure for P17482

Immunogen

HOXB9 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 147-176 amino acids from the Central region of human HOXB9.

Conjugate

HRP

Note

Preservative Free

Product Categories/Family for anti-HOXB9 antibody

Antibodies; Transcription Factors; Zinc; Ring; Homeobox

Applications Tested/Suitable for anti-HOXB9 antibody

Western Blot (WB), ELISA (EIA)

Application Notes for anti-HOXB9 antibody

WB: 1:100-500
ELISA: 1:1,000
Applications are based on unconjugated antibody.

Product References and Citations for anti-HOXB9 antibody

Hayashida, T., et al. Proc. Natl. Acad. Sci. U.S.A. 107(3):1100-1105(2010). Need, A.C., et al. Hum. Mol. Genet. 18(23):4650-4661(2009). Rouault, K., et al. Osteoarthr. Cartil. 17(8):1099-1105(2009). Nguyen, D.X., et al. Cell 138(1):51-62(2009). Venkatesan, K., et al. Nat. Methods 6(1):83-90(2009).

Other Notes

Small volumes of anti-HOXB9 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for HOXB9 purchase

MBS6307939 is an antibody targeting HOXB9. Also known as HOXB9, ID (HOXB9, HOX2E, Homeobox protein Hox-B9, Homeobox protein Hox-2.5, Homeobox protein Hox-2E) (Azide free) (HRP). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for HOXB9. It may not necessarily be applicable to this product.

NCBI GI #

15029508

NCBI GeneID

3219

NCBI Accession #

NP_076922.1

UniProt Primary Accession #

P17482

UniProt Secondary Accession #

Q9H1I1; B2RDB7

UniProt Related Accession #

P17482

GenBank Nucleotide #

NM_024017.4

NCBI Official Full Name

homeobox protein Hox-B9

NCBI Official Synonym Full Names

homeobox B9

NCBI Official Symbol

HOXB9

NCBI Official Synonym Symbols

HOX2; HOX2E; HOX-2.5

UniProt Protein Name

Homeobox protein Hox-B9

UniProt Synonym Protein Names

Homeobox protein Hox-2.5; Homeobox protein Hox-2E

Protein Family

Homeobox protein

UniProt Gene Name

HOXB9

UniProt Synonym Gene Names

HOX2E

UniProt Entry Name

HXB9_HUMAN

NCBI Protein Information

homeobox protein Hox-B9; homeo box 2E; homeo box B9; homeobox protein Hox-2E; homeobox protein Hox-2.5

NCBI Summary for HOXB9

This gene is a member of the Abd-B homeobox family and encodes a protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded nuclear protein functions as a sequence-specific transcription factor that is involved in cell proliferation and differentiation. Increased expression of this gene is associated with some cases of leukemia, prostate cancer and lung cancer. [provided by RefSeq, Jul 2008]

UniProt Comments for HOXB9

HOXB9: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Belongs to the Abd-B homeobox family.

Protein type: DNA-binding

Chromosomal Location of Human Ortholog: 17q21.3

Cellular Component: nucleoplasm; mitochondrion

Molecular Function: protein binding; sequence-specific DNA binding

Biological Process: anterior/posterior pattern formation; mammary gland development; transcription, DNA-dependent; embryonic skeletal development; positive regulation of transcription from RNA polymerase II promoter; Wnt receptor signaling pathway through beta-catenin

Research Articles on HOXB9

1. The expression of HOXB9, its relationship to clinical factors in breast cancer and efficacy as a prognostic factor were discussed.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-HOXB9 antibody

Reference Product	PubMed Publications
BTG2 antibody	>3 publications with HOXB9 and BTG2
BTG1 antibody	>3 publications with HOXB9 and BTG1

Diseases associated with anti-HOXB9 antibody

Disease Name	Pubmed Publications
Neoplasms Antibodies	>16 publications with HOXB9 and Neoplasms
Breast Neoplasms Antibodies	>6 publications with HOXB9 and Breast Neoplasms
Congenital Abnormalities Antibodies	>5 publications with HOXB9 and Congenital Abnormalities
Lung Diseases Antibodies	>4 publications with HOXB9 and Lung Diseases
Neoplasm Metastasis Antibodies	>3 publications with HOXB9 and Neoplasm Metastasis
Liver Diseases Antibodies	>1 publications with HOXB9 and Liver Diseases
Prostatic Diseases Antibodies	>1 publications with HOXB9 and Prostatic Diseases
Cognition Disorders Antibodies	>1 publications with HOXB9 and Cognition Disorders
Immune System Diseases Antibodies	>1 publications with HOXB9 and Immune System Diseases
Ataxia Antibodies	>1 publications with HOXB9 and Ataxia

Organs/Tissues associated with anti-HOXB9 antibody

Organ/Tissue Name	Pubmed Publications
Embryonic Tissue Antibodies	>20 publications with HOXB9 and Embryonic Tissue
Brain Antibodies	>10 publications with HOXB9 and Brain
Bone Antibodies	>9 publications with HOXB9 and Bone
Lung Antibodies	>6 publications with HOXB9 and Lung
Mammary Gland Antibodies	>4 publications with HOXB9 and Mammary Gland
Stomach Antibodies	>1 publications with HOXB9 and Stomach
Prostate Antibodies	>1 publications with HOXB9 and Prostate
Muscle Antibodies	>1 publications with HOXB9 and Muscle