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HTATIP2 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS643487

Oxidoreductase required for tumor suppression. NAPDH-bound form inhibits nuclear import by competing with nuclear import substrates for binding to a subset of nuclear transport receptors. May act as a redox sensor linked to transcription through regulation of… More details

$895 / 0.2 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
HTATIP2, Polyclonal Antibody
Full Product Name
HTATIP2, NT (HTATIP2, CC3, TIP30, Oxidoreductase HTATIP2, 30kD HIV-1 TAT-interacting protein, HIV-1 TAT-interactive protein 2)
Product Gene Name
anti-HTATIP2 antibody
Product Synonym Names
Anti -HTATIP2, NT (HTATIP2, CC3, TIP30, Oxidoreductase HTATIP2, 30kD HIV-1 TAT-interacting protein, HIV-1 TAT-interactive protein 2)
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity/Purification
Affinity Purified
Purified by Protein A affinity chromatography.
Specificity
Human
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
27,049 Da
OMIM
605628
3D Structure
ModBase 3D Structure for Q9BUP3
Immunogen
HTATIP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 44-74 amino acids from the N-terminal region of human HTATIP2.

Product Categories/Family for anti-HTATIP2 antibody

Antibodies; Abs to Infectious Disease HIV
Applications Tested/Suitable for anti-HTATIP2 antibody
ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-HTATIP2 antibody
Suitable for use in Western Blot, Immunohistochemistry, ELISA
Dilution: ELISA: 1:1,000
Western Blot: 1:100-500
Immunohistochemistry: 1:10-50

Western Blot (WB) of anti-HTATIP2 antibody

HTATIP2 Antibody (N-term) western blot analysis in Jurkat cell line lysates (35ug/lane).This demonstrates the HTATIP2 antibody detected the HTATIP2 protein (arrow).
Rabbit Anti-HTATIP2 Polyclonal Antibody – Cat# MBS643487

Immunohistochemistry (IHC) of anti-HTATIP2 antibody

HTATIP2 Antibody (N-term) (AP14762a)immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of HTATIP2 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.
Rabbit Anti-HTATIP2 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS643487

Other Notes

Small volumes of anti-HTATIP2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for HTATIP2 purchase

MBS643487 is an antibody targeting HTATIP2. Also known as HTATIP2, NT (HTATIP2, CC3, TIP30, Oxidoreductase HTATIP2, 30kD HIV-1 TAT-interacting protein, HIV-1 TAT-interactive protein 2). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for HTATIP2. It may not necessarily be applicable to this product.

NCBI GI #
48145759
NCBI Accession #
CAG33102.1
UniProt Primary Accession #
Q9BUP3
UniProt Secondary Accession #
O15383; O60520; O95345; Q53GC1; Q53GG2; Q6IBI3; A8K7S7; D3DQY8
NCBI Official Full Name
HTATIP2
UniProt Protein Name
Oxidoreductase HTATIP2
UniProt Synonym Protein Names
30 kDa HIV-1 TAT-interacting protein; HIV-1 TAT-interactive protein 2
Protein Family
Oxidoreductase
UniProt Gene Name
HTATIP2
UniProt Synonym Gene Names
CC3; TIP30
UniProt Entry Name
HTAI2_HUMAN

UniProt Comments for HTATIP2

HTATIP2: Oxidoreductase required for tumor suppression. NAPDH- bound form inhibits nuclear import by competing with nuclear import substrates for binding to a subset of nuclear transport receptors. May act as a redox sensor linked to transcription through regulation of nuclear import. Isoform 1 is a metastasis suppressor with proapoptotic as well as antiangiogenic properties. Isoform 2 has an antiapoptotic effect. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 1.1.1.-; Tumor suppressor; Nuclear envelope; Transcription factor; Apoptosis; Oxidoreductase

Chromosomal Location of Human Ortholog: 11p15.1

Cellular Component: membrane; cytoplasm; nuclear envelope; nucleus

Molecular Function: protein binding; transcription coactivator activity; oxidoreductase activity

Biological Process: regulation of transcription from RNA polymerase II promoter; viral reproduction; apoptosis; nuclear import; angiogenesis; cell differentiation; regulation of angiogenesis; negative regulation of apoptosis
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-HTATIP2 antibody

 Reference Product  PubMed Publications
 TAT antibody  >14 publications with HTATIP2 and TAT
 RAB5A antibody  >2 publications with HTATIP2 and RAB5A
 ACSL4 antibody  >2 publications with HTATIP2 and ACSL4
 ETS1 antibody  >1 publications with HTATIP2 and ETS1
 NCOA5 antibody  >1 publications with HTATIP2 and NCOA5

Diseases associated with anti-HTATIP2 antibody

 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >33 publications with HTATIP2 and Neoplasms
 Carcinoma Antibodies  >23 publications with HTATIP2 and Carcinoma
 Adenocarcinoma Antibodies  >14 publications with HTATIP2 and Adenocarcinoma
 Carcinoma, Hepatocellular Antibodies  >12 publications with HTATIP2 and Carcinoma, Hepatocellular
 Liver Diseases Antibodies  >11 publications with HTATIP2 and Liver Diseases
 Liver Neoplasms Antibodies  >11 publications with HTATIP2 and Liver Neoplasms
 Neoplasm Metastasis Antibodies  >11 publications with HTATIP2 and Neoplasm Metastasis
 Lung Neoplasms Antibodies  >10 publications with HTATIP2 and Lung Neoplasms
 Breast Neoplasms Antibodies  >7 publications with HTATIP2 and Breast Neoplasms
 Nervous System Diseases Antibodies  >7 publications with HTATIP2 and Nervous System Diseases

Organs/Tissues associated with anti-HTATIP2 antibody

 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >15 publications with HTATIP2 and Liver
 Lung Antibodies  >12 publications with HTATIP2 and Lung
 Brain Antibodies  >5 publications with HTATIP2 and Brain
 Lymph Node Antibodies  >4 publications with HTATIP2 and Lymph Node
 Prostate Antibodies  >4 publications with HTATIP2 and Prostate
 Stomach Antibodies  >2 publications with HTATIP2 and Stomach
 Spinal Cord Antibodies  >1 publications with HTATIP2 and Spinal Cord
 Mouth Antibodies  >1 publications with HTATIP2 and Mouth
 Mammary Gland Antibodies  >1 publications with HTATIP2 and Mammary Gland
 Intestine Antibodies  >1 publications with HTATIP2 and Intestine
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