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HTATIP2 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS9404356

TIP30 (30 kDa HIV-1 TAT-interacting protein), also known as HTATIP2 (HIV-1 TAT-interactive protein 2) or CC3, is a ubiquitously expressed protein that functions as an oxidoreductase. It acts as a tumor suppressor participating in metabolic suppression,… More details

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Product Overview

Online Datasheet in PDF
Product Name
HTATIP2, Polyclonal Antibody
Full Product Name
HTATIP2 Antibody
Product Gene Name
anti-HTATIP2 antibody
Product Synonym Names
CC3; TIP30; SDR44U1
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human
Form/Format
Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
Purity/Purification
Antigen affinity purification.
Concentration
2.1 mg/ml (lot specific)
Specificity
The antibody detects endogenous levels of total HTATIP2 protein.
Preparation and Storage
Store at -20 degree C
Molecular Weight
30,131 Da
OMIM
605628
3D Structure
ModBase 3D Structure for Q9BUP3
Immunogen Type
Protein
Immunogen Description
Fusion protein corresponding to residues near the C terminal of human HIV-1 Tat interactive protein 2, 30kDa
Target Name
HTATIP2

Product Categories/Family for anti-HTATIP2 antibody

Total protein Ab
Applications Tested/Suitable for anti-HTATIP2 antibody
Western Blot (WB)
Application Notes for anti-HTATIP2 antibody
Western blotting: 1:500-1:2000

Testing Data of anti-HTATIP2 antibody

Gel: 8%SDS-PAGE Lysate: 40ug A431 cellPrimary antibody: 1/800 dilution Secondary antibody dilution: 1/8000Exposure time: 5 seconds
Rabbit Anti-HTATIP2 Polyclonal Antibody – Cat# MBS9404356

Other Notes

Small volumes of anti-HTATIP2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for HTATIP2 purchase

MBS9404356 is an antibody targeting HTATIP2. Also known as HTATIP2 Antibody. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for HTATIP2. It may not necessarily be applicable to this product.

NCBI GI #
148728166
NCBI GeneID
10553
NCBI Accession #
NP_001091990.1
UniProt Primary Accession #
Q9BUP3
UniProt Secondary Accession #
O15383; O60520; O95345; Q53GC1; Q53GG2; Q6IBI3; A8K7S7; D3DQY8
UniProt Related Accession #
Q9BUP3
GenBank Nucleotide #
NM_001098520.1
NCBI Official Full Name
oxidoreductase HTATIP2 isoform a
NCBI Official Synonym Full Names
HIV-1 Tat interactive protein 2, 30kDa
NCBI Official Symbol
HTATIP2
NCBI Official Synonym Symbols
CC3; TIP30; SDR44U1
UniProt Protein Name
Oxidoreductase HTATIP2
UniProt Synonym Protein Names
30 kDa HIV-1 TAT-interacting protein; HIV-1 TAT-interactive protein 2
Protein Family
Oxidoreductase
UniProt Gene Name
HTATIP2
UniProt Entry Name
HTAI2_HUMAN
NCBI Protein Information
oxidoreductase HTATIP2

UniProt Comments for HTATIP2

HTATIP2: Oxidoreductase required for tumor suppression. NAPDH- bound form inhibits nuclear import by competing with nuclear import substrates for binding to a subset of nuclear transport receptors. May act as a redox sensor linked to transcription through regulation of nuclear import. Isoform 1 is a metastasis suppressor with proapoptotic as well as antiangiogenic properties. Isoform 2 has an antiapoptotic effect. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Oxidoreductase; Apoptosis; Transcription factor; Tumor suppressor; EC 1.1.1.-; Nuclear envelope

Chromosomal Location of Human Ortholog: 11p15.1

Cellular Component: membrane; cytoplasm; nuclear envelope; nucleus

Molecular Function: protein binding; transcription coactivator activity; oxidoreductase activity

Biological Process: regulation of transcription from RNA polymerase II promoter; viral reproduction; apoptosis; nuclear import; angiogenesis; cell differentiation; regulation of angiogenesis; negative regulation of apoptosis
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Research Articles on HTATIP2

1. the present study showed that loss of HTATIP2 expression was a frequent event in glioma and is associated with poor prognosis.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-HTATIP2 antibody

 Reference Product  PubMed Publications
 MYC antibody  >4 publications with HTATIP2 and MYC
 RAB5A antibody  >2 publications with HTATIP2 and RAB5A
 ACSL4 antibody  >2 publications with HTATIP2 and ACSL4
 TP53 antibody  >1 publications with HTATIP2 and TP53

Diseases associated with anti-HTATIP2 antibody

 Disease Name  Pubmed Publications
 Adenocarcinoma Antibodies  >22 publications with HTATIP2 and Adenocarcinoma
 Liver Diseases Antibodies  >17 publications with HTATIP2 and Liver Diseases
 Liver Neoplasms Antibodies  >16 publications with HTATIP2 and Liver Neoplasms
 Neoplasm Metastasis Antibodies  >16 publications with HTATIP2 and Neoplasm Metastasis
 Carcinoma, Hepatocellular Antibodies  >16 publications with HTATIP2 and Carcinoma, Hepatocellular
 Nervous System Diseases Antibodies  >9 publications with HTATIP2 and Nervous System Diseases
 Cell Transformation, Neoplastic Antibodies  >3 publications with HTATIP2 and Cell Transformation, Neoplastic
 Fatty Liver Antibodies  >2 publications with HTATIP2 and Fatty Liver
 Hepatitis Antibodies  >2 publications with HTATIP2 and Hepatitis
 Necrosis Antibodies  >2 publications with HTATIP2 and Necrosis

Organs/Tissues associated with anti-HTATIP2 antibody

 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >20 publications with HTATIP2 and Liver
 Lung Antibodies  >13 publications with HTATIP2 and Lung
 Brain Antibodies  >6 publications with HTATIP2 and Brain
 Lymph Node Antibodies  >5 publications with HTATIP2 and Lymph Node
 Prostate Antibodies  >4 publications with HTATIP2 and Prostate
 Stomach Antibodies  >2 publications with HTATIP2 and Stomach
 Mouth Antibodies  >1 publications with HTATIP2 and Mouth
 Mammary Gland Antibodies  >1 publications with HTATIP2 and Mammary Gland
 Intestine Antibodies  >1 publications with HTATIP2 and Intestine
 Pancreas Antibodies  >1 publications with HTATIP2 and Pancreas
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