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IARS Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6481370

MBS6481370 is an antibody targeting IARS. Also known as IARS, NT (Isoleucyl-tRNA Synthetase Cytoplasmic, IARS1, IleRS, ILRS, IRS, FLJ20736, Isoleucine-tRNA Ligase, PRO0785) (PE). Reactive in Human. Host: Rabbit. More details

$1060 / 0.2 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
IARS, Polyclonal Antibody
Full Product Name
IARS, NT (Isoleucyl-tRNA Synthetase Cytoplasmic, IARS1, IleRS, ILRS, IRS, FLJ20736, Isoleucine-tRNA Ligase, PRO0785) (PE)
Product Gene Name
Product Synonym Names
EC=6.1.1.5
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with R-Phycoerythrin (PE).
Purity/Purification
Purified by Ammonium Sulfate Precipitation.
Specificity
Recognizes human IARS.
Preparation and Storage
Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: PE conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molecular Weight
144,498 Da
OMIM
D28473 mRNA
3D Structure
ModBase 3D Structure for P41252
Immunogen
Synthetic peptide selected from the N-term region of human IARS (KLH).
Conjugate
PE
Note
Preservative Free

Product Categories/Family for anti-IARS antibody

Applications Tested/Suitable for anti-IARS antibody
Immunohistochemistry (IHC), ELISA (EIA)
Application Notes for anti-IARS antibody
IHC: 1:10-1:50
ELISA: 1:1,000
Applications are based on unconjugated antibody.

Product References and Citations for anti-IARS antibody

1. Shiba K., Proc. Natl. Acad. Sci. USA 91:7435-7439(1994). 2. Nichols R.C., Gene 155:299-304(1995).

Other Notes

Small volumes of anti-IARS antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for IARS. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
isoleucine--tRNA ligase, cytoplasmic
NCBI Official Synonym Full Names
isoleucyl-tRNA synthetase
NCBI Official Symbol
IARS
NCBI Official Synonym Symbols
IRS; ILRS; IARS1; ILERS; GRIDHH; PRO0785
UniProt Protein Name
Isoleucine--tRNA ligase, cytoplasmic
UniProt Synonym Protein Names
Isoleucyl-tRNA synthetase; IRS; IleRS
UniProt Gene Name
IARS
UniProt Synonym Gene Names
IRS; IleRS
NCBI Protein Information
isoleucine--tRNA ligase, cytoplasmic

NCBI Summary for IARS

Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAS, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Isoleucine-tRNA synthetase belongs to the class-I aminoacyl-tRNA synthetase family and has been identified as a target of autoantibodies in the autoimmune disease polymyositis/dermatomyositis. Alternatively spliced transcript variants have been found. [provided by RefSeq, Nov 2012]
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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