Rabbit Anti-IFN21 Polyclonal Antibody – Cat# MBS9419014

Western blot analysis IFN21 using Jurkat whole cell lysates

IFN21 Antibody – Rabbit Polyclonal

Name: IFN21 Antibody; Polyclonal; Rabbit; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS9419014
Price: 260 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS9419014

MBS9419014 is an antibody targeting IFN21. Also known as IFN21 Antibody. Reactive in Human. Host: Rabbit. More details

$260 / 0.05 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

IFN21, Polyclonal Antibody

Full Product Name

IFN21 Antibody

Product Gene Name

anti-IFN21 antibody

Product Synonym Names

IFN-alpha-21 � �IFN-alpha-1/13

Clonality

Polyclonal

Host

Rabbit

Species Reactivity

Human

Form/Format

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Concentration

1.0mg/mL (lot specific)

Specificity

IFN21 Antibody detects endogenous levels of total IFN21

Preparation and Storage

Store at -20 degree C

Molecular Weight

21,741 Da

OMIM

V00540 mRNA

3D Structure

ModBase 3D Structure for P01568

Immunogen

A synthesized peptide derived from human IFN21

Immunogen Type

Peptide

Product Categories/Family for anti-IFN21 antibody

Total protein Ab

Applications Tested/Suitable for anti-IFN21 antibody

Western Blot (WB)

Application Notes for anti-IFN21 antibody

Western Blot: 1:1000-3000

Other Notes

Small volumes of anti-IFN21 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for IFN21. It may not necessarily be applicable to this product.

NCBI GI #

169791013

NCBI GeneID

3452

NCBI Accession #

NP_002166.2

UniProt Primary Accession #

P01568

UniProt Secondary Accession #

Q14608; Q5VWD1; Q7M4Q4

UniProt Related Accession #

P01568

GenBank Nucleotide #

NM_002175.2

NCBI Official Full Name

interferon alpha-21

NCBI Official Synonym Full Names

interferon alpha 21

NCBI Official Symbol

IFNA21

NCBI Official Synonym Symbols

LeIF F; leIF-F; IFN-alphaI

UniProt Protein Name

Interferon alpha-21

UniProt Synonym Protein Names

Interferon alpha-F; LeIF F

UniProt Gene Name

IFNA21

UniProt Synonym Gene Names

IFN-alpha-21; LeIF F

UniProt Entry Name

IFN21_HUMAN

NCBI Protein Information

interferon alpha-21

NCBI Summary for IFN21

This gene is a member of the alpha interferon gene cluster on the short arm of chromosome 9. Interferons are cytokines produced in response to viral infection that mediate the immune response and interfere with viral replication. The encoded protein is a type I interferon and may play a specific role in the antiviral response to rubella virus. [provided by RefSeq, Sep 2011]

UniProt Comments for IFN21

IFNA21: Produced by macrophages, IFN-alpha have antiviral activities. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase. Belongs to the alpha/beta interferon family.

Protein type: Cytokine; Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 9p22

Cellular Component: extracellular region; extracellular space

Molecular Function: cytokine activity; hematopoietin/interferon-class (D200-domain) cytokine receptor binding; interferon-alpha/beta receptor binding

Biological Process: adaptive immune response; B cell differentiation; B cell proliferation; blood coagulation; cytokine and chemokine mediated signaling pathway; humoral immune response; innate immune response; natural killer cell activation during immune response; positive regulation of peptidyl-serine phosphorylation of STAT protein; response to exogenous dsRNA; T cell activation during immune response

Research Articles on IFN21

1. Structural AA changes in the C-helix interacting with IFNAlphaR1 may change the signaling dynamics leading to elevated APOBEC3 & lower IDO by an engineered mutant derived from the amino-terminal region of IFNalpha21b and the COOH-terminus from IFNalpha2c.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-IFN21 antibody

Reference Product	PubMed Publications
IFNAR1 antibody	>1 publications with IFN21 and IFNAR1

Pathways associated with anti-IFN21 antibody

Products by Pathway	Pathway Diagram
Autoimmune Thyroid Disease Pathway antibodies	Autoimmune Thyroid Disease Pathway Diagram
Autoimmune Thyroid Disease Pathway antibodies	Autoimmune Thyroid Disease Pathway Diagram
Autophagy Pathway antibodies	Autophagy Pathway Diagram
Autophagy Pathway antibodies	Autophagy Pathway Diagram
Cytokine Signaling In Immune System Pathway antibodies	Cytokine Signaling In Immune System Pathway Diagram
Cytokine-cytokine Receptor Interaction Pathway antibodies	Cytokine-cytokine Receptor Interaction Pathway Diagram
Cytokine-cytokine Receptor Interaction Pathway antibodies	Cytokine-cytokine Receptor Interaction Pathway Diagram
Cytosolic DNA-sensing Pathway antibodies	Cytosolic DNA-sensing Pathway Diagram
Cytosolic DNA-sensing Pathway antibodies	Cytosolic DNA-sensing Pathway Diagram
Factors Involved In Megakaryocyte Development And Platelet Production Pathway antibodies	Factors Involved In Megakaryocyte Development And Platelet Production Pathway Diagram

Diseases associated with anti-IFN21 antibody

Disease Name	Pubmed Publications
Genetic Predisposition to Disease Antibodies	>2 publications with IFN21 and Genetic Predisposition to Disease
Dementia Antibodies	>1 publications with IFN21 and Dementia