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IgA1/2 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS9233660

MBS9233660 is an antibody targeting IgA1/2. Reactive in Human. Host: Rabbit. Rabbit polyclonal antibody to IgA1 More details

$475 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
IgA1/2, Polyclonal Antibody
Full Product Name
Anti-IgA1/2 Antibody
Product Gene Name
Product Synonym Gene Name
IGHA1, IGHA2
Product Synonym Names
IGHA1; Ig alpha-1 chain C region; IGHA2; Ig alpha-2 chain C region
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 2 weeks. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Molecular Weight
160,000
Chromosome Location
Chromosome: 14; NC_000014.8 (106173505..106175001, complement). Location: 14q32.33
OMIM
146900
3D Structure
ModBase 3D Structure for P01876
Notes
ECO:0000303|PubMed:11340299, ECO:0000303|Ref.12
Applications Tested/Suitable for anti-IgA1/2 antibody
Western Blot (WB), Immunohistochemistry (IHC)

Wester Blot (WB) of anti-IgA1/2 antibody

Dilution: WB 1/500 - 1/1000
Western blot analysis of IgA1 expression in AML12 (A), SGC7901 (B), A549 (C), HepG2 (D) whole cell lysates.
Rabbit Anti-IgA1/2 Polyclonal Antibody – Cat# MBS9233660

Immunohistochemistry (IHC) of anti-IgA1/2 antibody

Dilution: IH 1/50 - 1/200
Immunohistochemical analysis of IgA1 staining in human lung cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.
Rabbit Anti-IgA1/2 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS9233660

Other Notes

Small volumes of anti-IgA1/2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for IgA1/2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
NCBI Official Full Name
Ig alpha-1 chain C region
NCBI Official Synonym Full Names
immunoglobulin heavy constant alpha 1
NCBI Official Symbol
IGHA1
NCBI Official Synonym Symbols
IgA1
UniProt Protein Name
Ig alpha-1 chain C region
UniProt Gene Name
IGHA1
UniProt Entry Name
IGHA1_HUMAN

UniProt Comments for IgA1/2

IGHA1: Ig alpha is the major immunoglobulin class in body secretions. It may serve both to defend against local infection and to prevent access of foreign antigens to the general immunologic system. A chromosomal aberration involving IGHA1 is found in multiple myeloma (MM) cell lines. Translocation t(1;14)(q21;q32) that forms a FCRL4-IGHA1 fusion protein.

Protein type: Immunoglobulin superfamily

Chromosomal Location of Human Ortholog: 14q32.33

Cellular Component: extracellular space; extracellular region

Molecular Function: antigen binding

Biological Process: retinal homeostasis; receptor-mediated endocytosis; glomerular filtration; antibacterial humoral response; immune response; protein-chromophore linkage
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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