Rabbit Anti-IGSF5 Polyclonal Antibody – Cat# MBS6309585

IGSF5 Antibody (N-term) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the IGSF5 antibody detected the IGSF5 protein (arrow).

IGSF5 Antibody – Rabbit Polyclonal

Name: IGSF5 Antibody; Polyclonal; Rabbit; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS6309585
Price: 1060 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6309585

Provides, together with MAGI1, an adhesion machinery at tight junctions, which may regulate the permeability of kidney glomerulus and small intestinal epithelial cells. Mediates calcium-independent homophilic cell adhesion. In testis, it may function as a… More details

$1060 / 0.2 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

IGSF5, Polyclonal Antibody

Full Product Name

IGSF5, NT (IGSF5, JAM4, Immunoglobulin superfamily member 5, Junctional adhesion molecule 4) (AP)

Product Gene Name

anti-IGSF5 antibody

Product Synonym Names

IGSF5; JAM4; Immunoglobulin superfamily member 5; Junctional adhesion molecule 4

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human

Form/Format

Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Alkaline Phosphatase (AP).

Purity/Purification

Purified by Protein A Affinity Chromatography.

Preparation and Storage

Store product at 4 degree C. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Molecular Weight

44,593 Da

OMIM

610638

3D Structure

ModBase 3D Structure for Q9NSI5

Immunogen

IGSF5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human IGSF5.

Conjugate

Note

Preservative Free

Product Categories/Family for anti-IGSF5 antibody

Antibodies; Connexin; Junction Proteins

Applications Tested/Suitable for anti-IGSF5 antibody

Western Blot (WB), ELISA (EIA)

Application Notes for anti-IGSF5 antibody

WB: 1:100-500
ELISA: 1:1,000
Applications are based on unconjugated antibody.

Product References and Citations for anti-IGSF5 antibody

Rose, J. Phd, et al. Mol. Med. (2010).

Other Notes

Small volumes of anti-IGSF5 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for IGSF5 purchase

MBS6309585 is an antibody targeting IGSF5. Also known as IGSF5, NT (IGSF5, JAM4, Immunoglobulin superfamily member 5, Junctional adhesion molecule 4) (AP). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for IGSF5. It may not necessarily be applicable to this product.

NCBI GI #

122937285

NCBI GeneID

150084

NCBI Accession #

NP_001073913.1

UniProt Primary Accession #

Q9NSI5

UniProt Related Accession #

Q9NSI5

GenBank Nucleotide #

NM_001080444.1

NCBI Official Full Name

immunoglobulin superfamily member 5

NCBI Official Synonym Full Names

immunoglobulin superfamily, member 5

NCBI Official Symbol

IGSF5

NCBI Official Synonym Symbols

GSF5; JAM4

UniProt Protein Name

Immunoglobulin superfamily member 5

UniProt Synonym Protein Names

Junctional adhesion molecule 4; JAM-4

Protein Family

Immunoglobulin superfamily

UniProt Gene Name

IGSF5

UniProt Synonym Gene Names

JAM4; IgSF5; JAM-4

UniProt Entry Name

IGSF5_HUMAN

NCBI Protein Information

immunoglobulin superfamily member 5; JAM-4; junctional adhesion molecule 4; immunoglobulin superfamily 5 like

UniProt Comments for IGSF5

IGSF5: Provides, together with MAGI1, an adhesion machinery at tight junctions, which may regulate the permeability of kidney glomerulus and small intestinal epithelial cells. Mediates calcium-independent homophilic cell adhesion. In testis, it may function as a cell adhesion molecule rather than a tight-junction protein. It may participate in the adhesion between spermatogonia- spermatogonia, spermatogonia-Sertoli cells, and Sertoli cells- Sertoli cells. Belongs to the immunoglobulin superfamily.

Protein type: Membrane protein, integral; Cell surface; Immunoglobulin superfamily; Cell adhesion

Chromosomal Location of Human Ortholog: 21q22.2

Cellular Component: neuron projection; tight junction; cell surface; cell soma; integral to membrane; plasma membrane; intercellular junction

Molecular Function: PDZ domain binding

Biological Process: cell-cell adhesion; regulation of neurogenesis

Research Articles on IGSF5

1. Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-IGSF5 antibody

Products by Pathway	Pathway Diagram
Epithelial Cell Signaling In Helicobacter Pylori Infection Pathway antibodies	Epithelial Cell Signaling In Helicobacter Pylori Infection Pathway Diagram
Epithelial Cell Signaling In Helicobacter Pylori Infection Pathway antibodies	Epithelial Cell Signaling In Helicobacter Pylori Infection Pathway Diagram
Tight Junction Pathway antibodies	Tight Junction Pathway Diagram
Tight Junction Pathway antibodies	Tight Junction Pathway Diagram

Organs/Tissues associated with anti-IGSF5 antibody

Organ/Tissue Name	Pubmed Publications
Kidney Antibodies	>3 publications with IGSF5 and Kidney
Testis Antibodies	>1 publications with IGSF5 and Testis