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IL17RA Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS7049603

MBS7049603 is an antibody targeting IL17RA. Also known as IL17RA Antibody. Reactive in Human, Mouse. Host: Rabbit. More details

$230 / 0.05 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
IL17RA, Polyclonal Antibody
Full Product Name
IL17RA Antibody
Product Gene Name
Product Synonym Names
Interleukin-17 receptor A; IL-17 receptor A; IL-17RA; CDw217; CD217; IL17RA; IL17R
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse
Form/Format
Liquid
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Purity/Purification
>95%, Protein G purified
Preparation and Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Matching Pairs
Unconjugated Antibody: IL17RA (MBS7049603)
HRP Conjugated Antibody: IL17RA (MBS7049604)
Matching Pairs
Unconjugated Antibody: IL17RA (MBS7049603)
FITC Conjugated Antibody: IL17RA (MBS7049605)
OMIM
U58917 mRNA
3D Structure
ModBase 3D Structure for Q96F46
Immunogen
Recombinant Human Interleukin-17 receptor A protein (552-743AA)
Immunogen Species
Homo sapiens (Human)
Research Area
Immunology
Target Names
IL17RA
Conjugate
Non-conjugated
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-IL17RA antibody
ELISA (EIA), Western Blot (WB), Immunofluorescence (IF)
Application Notes for anti-IL17RA antibody
WB: 1:500-1:5000
IF: 1:50-1:200

Western Blot (WB) of anti-IL17RA antibody

Western Blot
Positive WB detected in: NIH/3T3 whole cell lysate,HL-60 whole cell lysate
All lanes: IL17RA antibody at 3.5ug/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 97,93 KDa
Observed band size: 93 KDa
Rabbit Anti-IL17RA Polyclonal Antibody – Cat# MBS7049603

Immunofluorescence (IF) of anti-IL17RA antibody

Immunofluorescent analysis of HepG2 cells using MBS7049603 at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
Rabbit Anti-IL17RA Polyclonal Antibody, Immunofluorescence (IF) – Cat# MBS7049603

Other Notes

Small volumes of anti-IL17RA antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for IL17RA. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
interleukin-17 receptor A isoform 2
NCBI Official Synonym Full Names
interleukin 17 receptor A
NCBI Official Symbol
IL17RA
NCBI Official Synonym Symbols
CD217; IL17R; IMD51; CANDF5; CDw217; IL-17RA; hIL-17R
UniProt Protein Name
Interleukin-17 receptor A
UniProt Synonym Protein Names
CDw217; CD_antigen: CD217
UniProt Gene Name
IL17RA
UniProt Synonym Gene Names
IL17R; IL-17 receptor A; IL-17RA
UniProt Entry Name
I17RA_HUMAN
NCBI Protein Information
interleukin-17 receptor A

NCBI Summary for IL17RA

Interleukin 17A (IL17A) is a proinflammatory cytokine secreted by activated T-lymphocytes. It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils. The transmembrane protein encoded by this gene (interleukin 17A receptor; IL17RA) is a ubiquitous type I membrane glycoprotein that binds with low affinity to interleukin 17A. Interleukin 17A and its receptor play a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis. Like other cytokine receptors, this receptor likely has a multimeric structure. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Feb 2014]
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UniProt Comments for IL17RA

IL17RA: Receptor for IL17A and IL17F. Binds its IL17A ligand with low affinity, suggesting that additional components are involved in IL17A-induced signaling. Widely expressed.

Protein type: Membrane protein, integral; Receptor, cytokine

Chromosomal Location of Human Ortholog: 22q11.1

Cellular Component: integral to plasma membrane; plasma membrane

Molecular Function: interleukin-17 receptor activity; protein binding

Biological Process: positive regulation of interleukin-23 production

Disease: Candidiasis, Familial, 5
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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