Rabbit Anti-ING5 Polyclonal Antibody – Cat# MBS7050727

Immunofluorescent analysis of Hela cells using MBS7050727 at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)

ING5 Antibody – Rabbit Polyclonal

Name: ING5 Antibody; Polyclonal; Rabbit; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS7050727
Price: 230 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS7050727

Component of the HBO1 complex which has a histone H4-specific acetyltransferase activity, a reduced activity toward histone H3 and is responsible for the bulk of histone H4 acetylation in vivo. Component of the MOZ/MORF complex which has a histone H3… More details

$230 / 0.05 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

ING5, Polyclonal Antibody

Full Product Name

ING5 Antibody

Product Gene Name

anti-ING5 antibody

Product Synonym Names

Inhibitor of growth protein 5; p28ING5; ING5

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human

Form/Format

Liquid

Purity/Purification

>95%, Protein G purified

Preparation and Storage

Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.

Matching Pairs

Unconjugated Antibody: ING5 (MBS7050727)
HRP Conjugated Antibody: ING5 (MBS7050728)

Matching Pairs

Unconjugated Antibody: ING5 (MBS7050727)
FITC Conjugated Antibody: ING5 (MBS7050729)

Molecular Weight

25,932 Da

OMIM

AF189286 mRNA

3D Structure

ModBase 3D Structure for Q8WYH8

Immunogen

Recombinant Human Inhibitor of growth protein 5 protein (32-207AA)

Preservative

0.03% Proclin 300

Constituents

50% Glycerol, 0.01M PBS, pH 7.4

Conjugation

Non-conjugated

Santa Cruz Alternative

Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-324885 / sc-324887

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Applications Tested/Suitable for anti-ING5 antibody

ELISA (EIA), Immunofluorescence (IF)

Application Notes for anti-ING5 antibody

IF: 1: 50-1: 200

Other Notes

Small volumes of anti-ING5 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for ING5 purchase

MBS7050727 is an antibody targeting ING5. Also known as ING5 Antibody. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for ING5. It may not necessarily be applicable to this product.

NCBI GI #

1054467226

NCBI GeneID

84289

NCBI Accession #

NP_001317091.1

UniProt Primary Accession #

Q8WYH8

UniProt Secondary Accession #

Q53NU6; Q57Z54; Q9BS30; A8K1P3

UniProt Related Accession #

Q8WYH8

GenBank Nucleotide #

NM_001330162.1

NCBI Official Full Name

inhibitor of growth protein 5 isoform 3

NCBI Official Synonym Full Names

inhibitor of growth family member 5

NCBI Official Symbol

ING5

NCBI Official Synonym Symbols

p28ING5

UniProt Protein Name

Inhibitor of growth protein 5

UniProt Synonym Protein Names

p28ING5

Protein Family

Inhibitor of growth protein

UniProt Gene Name

ING5

UniProt Entry Name

ING5_HUMAN

NCBI Protein Information

inhibitor of growth protein 5

NCBI Summary for ING5

This gene encodes a tumor suppressor protein that inhibits cell growth and induces apoptosis. This protein contains a PHD-type zinc finger. It interacts with tumor suppressor p53 and p300, a component of the histone acetyl transferase complex, suggesting a role in transcriptional regulation. Alternative splicing and the use of multiple promoters and 3' terminal exons results in multiple transcript variants. [provided by RefSeq, Aug 2016]

UniProt Comments for ING5

ING5: Component of the HBO1 complex which has a histone H4- specific acetyltransferase activity, a reduced activity toward histone H3 and is responsible for the bulk of histone H4 acetylation in vivo. Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity. Through chromatin acetylation it may regulate DNA replication and may function as a transcriptional coactivator. Belongs to the ING family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Tumor suppressor

Chromosomal Location of Human Ortholog: 2q37.3

Cellular Component: nucleoplasm; nucleus

Molecular Function: methylated histone residue binding; protein binding

Biological Process: DNA replication; negative regulation of cell proliferation; negative regulation of growth; positive regulation of apoptosis; positive regulation of transcription, DNA-dependent; protein amino acid acetylation

Research Articles on ING5

1. miR-331-3p is upregulated by HBV and promotes proliferation of hepatocellular carcinoma cells though repression of ING5 expression.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-ING5 antibody

Reference Product	PubMed Publications
BRPF1 antibody	>6 publications with ING5 and BRPF1
KAT6A antibody	>5 publications with ING5 and KAT6A
KAT6B antibody	>4 publications with ING5 and KAT6B
KAT7 antibody	>3 publications with ING5 and KAT7
TP53 antibody	>2 publications with ING5 and TP53
PHF17 antibody	>1 publications with ING5 and PHF17
BRPF3 antibody	>1 publications with ING5 and BRPF3

Pathways associated with anti-ING5 antibody

Products by Pathway	Pathway Diagram
Chromatin Modifying Enzymes Pathway antibodies	Chromatin Modifying Enzymes Pathway Diagram
Chromatin Organization Pathway antibodies	Chromatin Organization Pathway Diagram
Gene Expression Pathway antibodies	Gene Expression Pathway Diagram
Generic Transcription Pathway antibodies	Generic Transcription Pathway Diagram
HATs Acetylate Histones Pathway antibodies	HATs Acetylate Histones Pathway Diagram
Regulation Of TP53 Activity Pathway antibodies	Regulation Of TP53 Activity Pathway Diagram
Regulation Of TP53 Activity Through Acetylation Pathway antibodies	Regulation Of TP53 Activity Through Acetylation Pathway Diagram
Transcriptional Regulation By TP53 Pathway antibodies	Transcriptional Regulation By TP53 Pathway Diagram

Diseases associated with anti-ING5 antibody

Disease Name	Pubmed Publications
Carcinoma, Squamous Cell Antibodies	>6 publications with ING5 and Carcinoma, Squamous Cell
Neoplasm Metastasis Antibodies	>4 publications with ING5 and Neoplasm Metastasis
Cell Transformation, Neoplastic Antibodies	>3 publications with ING5 and Cell Transformation, Neoplastic
Lung Neoplasms Antibodies	>2 publications with ING5 and Lung Neoplasms
Neoplasms, Experimental Antibodies	>2 publications with ING5 and Neoplasms, Experimental
Abnormalities, Multiple Antibodies	>1 publications with ING5 and Abnormalities, Multiple
Male Urogenital Diseases Antibodies	>1 publications with ING5 and Male Urogenital Diseases
Growth Disorders Antibodies	>1 publications with ING5 and Growth Disorders
Liver Diseases Antibodies	>1 publications with ING5 and Liver Diseases
Carcinoma, Hepatocellular Antibodies	>1 publications with ING5 and Carcinoma, Hepatocellular

Organs/Tissues associated with anti-ING5 antibody

Organ/Tissue Name	Pubmed Publications
Lymph Node Antibodies	>5 publications with ING5 and Lymph Node
Lymph Antibodies	>5 publications with ING5 and Lymph
Brain Antibodies	>4 publications with ING5 and Brain
Lung Antibodies	>3 publications with ING5 and Lung
Stomach Antibodies	>2 publications with ING5 and Stomach
Mouth Antibodies	>2 publications with ING5 and Mouth
Bone Antibodies	>2 publications with ING5 and Bone
Embryonic Tissue Antibodies	>2 publications with ING5 and Embryonic Tissue
Eye Antibodies	>1 publications with ING5 and Eye
Skin Antibodies	>1 publications with ING5 and Skin