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INHBA Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6000976

The inhibin beta A subunit joins the alpha subunit to form a pituitary FSH secretion inhibitor. Inhibin has been shown to regulate gonadal stromal cell proliferation negatively and to have tumor-suppressor activity. In addition, serum levels of inhibin have… More details

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Sample Manual Insert View PDF
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Testing Data View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
INHBA, Polyclonal Antibody
Full Product Name
INHBA, NT (INHBA, Inhibin beta A chain, Activin beta-A chain, Erythroid differentiation protein)
Product Gene Name
Product Synonym Names
Anti -INHBA, NT (INHBA, Inhibin beta A chain, Activin beta-A chain, Erythroid differentiation protein)
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity/Purification
Affinity Purified
Purified by Protein A affinity chromatography.
Specificity
Human
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
47,710 Da
Chromosome Location
Chromosome: 4; NC_009147.2 (12878829..12889612, complement). Location: chromosome: 4
3D Structure
ModBase 3D Structure for P55102
Immunogen
INHBA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 92-119 amino acids from the N-terminal region of human INHBA.

Product Categories/Family for anti-INHBA antibody

Applications Tested/Suitable for anti-INHBA antibody
ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC), Flow Cytometry (FC/FACS), Immunofluorescence (IF)
Application Notes for anti-INHBA antibody
Suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence, Flow Cytometry, ELISA
Dilution: ELISA: 1:1,000
Western Blot: 1:100-500
Immunohistochemistry: 1:50-100
Flow Cytometry: 1:10-50
Immunofluorescence: 1:10-50

Western Blot (WB) of anti-INHBA antibody

Western Blot analysis in CEM cell line lysates (35ug/lane) using MBS6000976. This demonstrates that MBS6000976 detected the INHBA protein (arrow).
Rabbit Anti-INHBA Polyclonal Antibody – Cat# MBS6000976

Immunohistochemistry (IHC) of anti-INHBA antibody

Immunohistochemistry analysis in formalin fixed and paraffin embedded human stomach tissue using MBS6000976 followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of MBS6000976 for immunohistochemistry.
Rabbit Anti-INHBA Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS6000976

Immunofluorescence (IF) of anti-INHBA antibody

Confocal immunofluorescent analysis with HepG2 cells using MBS6000976 followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).
Rabbit Anti-INHBA Polyclonal Antibody, Immunofluorescence (IF) – Cat# MBS6000976

Flow Cytometry (FC/FACS) of anti-INHBA antibody

Flow Cytometry analysis of CEM cells using MBS6000976 (right histogram) compared to a negative control cell (left histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Rabbit Anti-INHBA Polyclonal Antibody, Flow Cytometry (FC/FACS) – Cat# MBS6000976

Other Notes

Small volumes of anti-INHBA antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for INHBA purchase

MBS6000976 is an antibody targeting INHBA. Also known as INHBA, NT (INHBA, Inhibin beta A chain, Activin beta-A chain, Erythroid differentiation protein). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for INHBA. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
inhibin beta A chain
NCBI Official Symbol
INHBA
UniProt Protein Name
Inhibin beta A chain
UniProt Synonym Protein Names
Activin beta-A chain
Protein Family
UniProt Gene Name
INHBA
UniProt Entry Name
INHBA_HORSE
NCBI Protein Information
inhibin beta A chain; activin beta-A chain; inhibin beta A subunit

UniProt Comments for INHBA

Function: Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins.

Subunit structure: Dimeric, linked by one or more disulfide bonds. Inhibin A is a dimer of alpha and beta-A. Inhibin B is a dimer of alpha and beta-B. Activin A is a homodimer of beta-A. Activin B is a homodimer of beta-B. Activin AB is a dimer of beta-A and beta-B. Interacts with FST and FSTL3

By similarity.

Subcellular location: Secreted

By similarity.

Sequence similarities: Belongs to the TGF-beta family.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-INHBA antibody

Organs/Tissues associated with anti-INHBA antibody

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