Rabbit Anti-IPMK Polyclonal Antibody – Cat# MBS6483449

Western blot analysis of IPMK Antibody (Center) in MCF-7 cell line lysates (35ug/lane). IPMK (arrow) was detected using the purified Pab.

IPMK Antibody – Rabbit Polyclonal

Name: IPMK Antibody; Polyclonal; Rabbit; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS6483449
Price: 1060 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6483449

MBS6483449 is an antibody targeting IPMK. Also known as IPMK (Inositol 1,3,4,6-tetrakisphosphate 5-kinase, Inositol Polyphosphate Multikinase, IMPK) (FITC). Reactive in Human. Host: Rabbit. More details

$1060 / 0.2 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

IPMK, Polyclonal Antibody

Full Product Name

IPMK (Inositol 1,3,4,6-tetrakisphosphate 5-kinase, Inositol Polyphosphate Multikinase, IMPK) (FITC)

Product Gene Name

anti-IPMK antibody

Product Synonym Names

EC=2.7.1.151

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human

Form/Format

Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Fluorescein Isothiocyanate (FITC).

Purity/Purification

Purified by Immunoaffinity chromatography.

Specificity

Recognizes human IPMK.

Preparation and Storage

Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: FITC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Molecular Weight

47,222 Da

Chromosome Location

Chromosome: 10; NC_000010.10 (59951278..60027694, complement). Location: 10q21.1

OMIM

609851

3D Structure

ModBase 3D Structure for Q8NFU5

Immunogen

Synthetic peptide selected from the center region of human IPMK (KLH).

Conjugate

FITC

Note

Preservative Free

Special Handling

Light sensitive

Product Categories/Family for anti-IPMK antibody

Antibodies; Protein Kinases

Applications Tested/Suitable for anti-IPMK antibody

Western Blot (WB), FLISA

Application Notes for anti-IPMK antibody

WB: 1:100-1:500
FLISA: 1:1,000
Applications are based on unconjugated antibody.

Product References and Citations for anti-IPMK antibody

1. Chang, S.C., et.al., J. Biol. Chem. 277(46), 43836-43843 (2002). 2. Nalaskowski, M.M., et.al., Biochem. J. 366(PT 2), 549-556 (2002).

Other Notes

Small volumes of anti-IPMK antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for IPMK. It may not necessarily be applicable to this product.

NCBI GI #

22726201

NCBI GeneID

253430

NCBI Accession #

NP_689416.1

UniProt Primary Accession #

Q8NFU5

UniProt Related Accession #

Q8NFU5

GenBank Nucleotide #

NM_152230.4

NCBI Official Full Name

inositol polyphosphate multikinase

NCBI Official Synonym Full Names

inositol polyphosphate multikinase

NCBI Official Symbol

IPMK

UniProt Protein Name

Inositol polyphosphate multikinase

UniProt Synonym Protein Names

Inositol 1,3,4,6-tetrakisphosphate 5-kinase

Protein Family

Inositol polyphosphate multikinase

UniProt Gene Name

IPMK

UniProt Synonym Gene Names

IMPK

UniProt Entry Name

IPMK_HUMAN

NCBI Protein Information

inositol polyphosphate multikinase; inositol 1,3,4,6-tetrakisphosphate 5-kinase

NCBI Summary for IPMK

This gene encodes a member of the inositol phosphokinase family. The encoded protein has 3-kinase, 5-kinase and 6-kinase activities on phosphorylated inositol substrates. The encoded protein plays an important role in the biosynthesis of inositol 1,3,4,5,6-pentakisphosphate, and has a preferred 5-kinase activity. This gene may play a role in nuclear mRNA export. Pseudogenes of this gene are located on the long arm of chromosome 13 and the short arm of chromosome 19. [provided by RefSeq, Dec 2010]

UniProt Comments for IPMK

IPMK: Inositol phosphate kinase with a broad substrate specificity. Has a preference for inositol 1,4,5-trisphosphate (Ins(1,4,5)P3) and inositol 1,3,4,6-tetrakisphosphate (Ins(1,3,4,6)P4). Belongs to the inositol phosphokinase (IPK) family.

Protein type: EC 2.7.1.151; Carbohydrate Metabolism - inositol phosphate; Kinase, other; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 10q21.1

Cellular Component: nucleoplasm; nucleolus; nucleus

Molecular Function: inositol tetrakisphosphate 3-kinase activity; inositol trisphosphate 6-kinase activity; inositol trisphosphate 3-kinase activity; ATP binding

Biological Process: inositol phosphate metabolic process; neural tube formation; phosphorylation; inositol phosphate biosynthetic process

Research Articles on IPMK

1. overview of possible roles of IPMK in regulation of metabolism: IPMK appears to mediate activation of mammalian target of rapamycin (mTOR) in response to essential amino acids. IPMK appears to mediate hypothalamic control of food intake. [REVIEW]

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-IPMK antibody

Products by Pathway	Pathway Diagram
1D-myo-inositol Hexakisphosphate Biosynthesis II (mammalian) Pathway antibodies	1D-myo-inositol Hexakisphosphate Biosynthesis II (mammalian) Pathway Diagram
1D-myo-inositol Hexakisphosphate Biosynthesis II (mammalian) Pathway antibodies	1D-myo-inositol Hexakisphosphate Biosynthesis II (mammalian) Pathway Diagram
1D-myo-inositol Hexakisphosphate Biosynthesis V (from Ins(1,3,4)P3) Pathway antibodies	1D-myo-inositol Hexakisphosphate Biosynthesis V (from Ins(1,3,4)P3) Pathway Diagram
D-myo-inositol (1,3,4)-trisphosphate Biosynthesis Pathway antibodies	D-myo-inositol (1,3,4)-trisphosphate Biosynthesis Pathway Diagram
D-myo-inositol (1,3,4)-trisphosphate Biosynthesis Pathway antibodies	D-myo-inositol (1,3,4)-trisphosphate Biosynthesis Pathway Diagram
D-myo-inositol (1,4,5,6)-tetrakisphosphate Biosynthesis Pathway antibodies	D-myo-inositol (1,4,5,6)-tetrakisphosphate Biosynthesis Pathway Diagram
D-myo-inositol (1,4,5,6)-tetrakisphosphate Biosynthesis Pathway antibodies	D-myo-inositol (1,4,5,6)-tetrakisphosphate Biosynthesis Pathway Diagram
D-myo-inositol (3,4,5,6)-tetrakisphosphate Biosynthesis Pathway antibodies	D-myo-inositol (3,4,5,6)-tetrakisphosphate Biosynthesis Pathway Diagram
D-myo-inositol (3,4,5,6)-tetrakisphosphate Biosynthesis Pathway antibodies	D-myo-inositol (3,4,5,6)-tetrakisphosphate Biosynthesis Pathway Diagram
Inositol Phosphate Metabolism Pathway antibodies	Inositol Phosphate Metabolism Pathway Diagram

Diseases associated with anti-IPMK antibody

Disease Name	Pubmed Publications
Neoplasms Antibodies	>1 publications with IPMK and Neoplasms

Organs/Tissues associated with anti-IPMK antibody

Organ/Tissue Name	Pubmed Publications
Brain Antibodies	>3 publications with IPMK and Brain
Kidney Antibodies	>2 publications with IPMK and Kidney
Liver Antibodies	>1 publications with IPMK and Liver
Vascular Antibodies	>1 publications with IPMK and Vascular