Rabbit Anti-KIF20A Polyclonal Antibody – Cat# MBS644162

KIF20A Antibody (N-term) western blot analysis in ZR-75-1 cell line lysates (35ug/lane).This demonstrates the KIF20A antibody detected the KIF20A protein (arrow).

KIF20A Antibody – Rabbit Polyclonal

Name: KIF20A Antibody; Polyclonal; Rabbit; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS644162
Price: 895 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS644162

KIF20A interacts with guanosine triphosphate (GTP)-bound forms of RAB6A and RAB6B. May act as a motor required for the retrograde RAB6 regulated transport of Golgi membranes and associated vesicles along microtubules. Has a microtubule plus end-directed… More details

$895 / 0.2 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

KIF20A, Polyclonal Antibody

Full Product Name

KIF20A, NT (KIF20A, MKLP2, RAB6KIFL, Kinesin-like protein KIF20A, GG10_2, Mitotic kinesin-like protein 2, Rab6-interacting kinesin-like protein, Rabkinesin-6)

Product Gene Name

anti-KIF20A antibody

Product Synonym Names

Anti -KIF20A, NT (KIF20A, MKLP2, RAB6KIFL, Kinesin-like protein KIF20A, GG10_2, Mitotic kinesin-like protein 2, Rab6-interacting kinesin-like protein, Rabkinesin-6)

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human

Form/Format

Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.

Purity/Purification

Affinity Purified
Purified by Protein A affinity chromatography.

Specificity

Human

Preparation and Storage

May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Molecular Weight

100,278 Da

Chromosome Location

Chromosome: 5; NC_000005.9 (137514408..137523404). Location: 5q31

OMIM

605664

3D Structure

ModBase 3D Structure for O95235

Immunogen

KIF20A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 197-226 amino acids from the N-terminal region of human KIF20A.

Product Categories/Family for anti-KIF20A antibody

Antibodies; Abs to GTPase; Rab; Ras; Rho Proteins

Applications Tested/Suitable for anti-KIF20A antibody

ELISA (EL/EIA), Western Blot (WB)

Application Notes for anti-KIF20A antibody

Suitable for use in Western Blot, ELISA
Dilution: ELISA: 1:1,000
Western Blot: 1:100-500

Other Notes

Small volumes of anti-KIF20A antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for KIF20A purchase

MBS644162 is an antibody targeting KIF20A. Also known as KIF20A, NT (KIF20A, MKLP2, RAB6KIFL, Kinesin-like protein KIF20A, GG10_2, Mitotic kinesin-like protein 2, Rab6-interacting kinesin-like protein, Rabkinesin-6). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for KIF20A. It may not necessarily be applicable to this product.

NCBI GI #

5032013

NCBI GeneID

10112

NCBI Accession #

NP_005724.1

UniProt Primary Accession #

O95235

UniProt Secondary Accession #

D3DQB6

UniProt Related Accession #

O95235

GenBank Nucleotide #

NM_005733.2

NCBI Official Full Name

kinesin-like protein KIF20A

NCBI Official Synonym Full Names

kinesin family member 20A

NCBI Official Symbol

KIF20A

NCBI Official Synonym Symbols

MKLP2; RAB6KIFL

UniProt Protein Name

Kinesin-like protein KIF20A

UniProt Synonym Protein Names

GG10_2; Mitotic kinesin-like protein 2; MKlp2; Rab6-interacting kinesin-like protein; Rabkinesin-6

Protein Family

Kinesin-like protein

UniProt Gene Name

KIF20A

UniProt Synonym Gene Names

MKLP2; RAB6KIFL; MKlp2

UniProt Entry Name

KI20A_HUMAN

NCBI Protein Information

kinesin-like protein KIF20A; GG10_2; rabkinesin-6; mitotic kinesin-like protein 2; rab6-interacting kinesin-like protein; RAB6 interacting, kinesin-like (rabkinesin6)

UniProt Comments for KIF20A

KIF20A: Mitotic kinesin required for chromosome passenger complex (CPC)-mediated cytokinesis. Following phosphorylation by PLK1, involved in recruitment of PLK1 to the central spindle. Interacts with guanosine triphosphate (GTP)-bound forms of RAB6A and RAB6B. May act as a motor required for the retrograde RAB6 regulated transport of Golgi membranes and associated vesicles along microtubules. Has a microtubule plus end-directed motility. Belongs to the kinesin-like protein family.

Protein type: Motor; Microtubule-binding

Chromosomal Location of Human Ortholog: 5q31

Cellular Component: nucleoplasm; Golgi apparatus; microtubule; kinesin complex; spindle; midbody

Molecular Function: protein binding; transporter activity; microtubule binding; ATPase activity; microtubule motor activity; protein kinase binding; ATP binding

Biological Process: vesicle-mediated transport; protein transport; cytokinesis after mitosis; cell separation during cytokinesis; metabolic process; cytokinesis; mitotic cell cycle; microtubule-based movement; microtubule bundle formation

Research Articles on KIF20A

1. Primary melanomas that were positive for KIF20A showed a significantly greater thickness than those that were negative, and patients with KIF20A+ melanoma tended to develop recurrence earlier.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-KIF20A antibody

Reference Product	PubMed Publications
RAB6A antibody	>3 publications with KIF20A and RAB6A
INCENP antibody	>2 publications with KIF20A and INCENP
PLK1 antibody	>2 publications with KIF20A and PLK1
CENPF antibody	>1 publications with KIF20A and CENPF
BUB1 antibody	>1 publications with KIF20A and BUB1
BIRC5 antibody	>1 publications with KIF20A and BIRC5
CDCA8 antibody	>1 publications with KIF20A and CDCA8

Pathways associated with anti-KIF20A antibody

Products by Pathway	Pathway Diagram
Adaptive Immune System Pathway antibodies	Adaptive Immune System Pathway Diagram
Aurora B Signaling Pathway antibodies	Aurora B Signaling Pathway Diagram
Cell Cycle Pathway antibodies	Cell Cycle Pathway Diagram
Cell Cycle, Mitotic Pathway antibodies	Cell Cycle, Mitotic Pathway Diagram
Factors Involved In Megakaryocyte Development And Platelet Production Pathway antibodies	Factors Involved In Megakaryocyte Development And Platelet Production Pathway Diagram
Hemostasis Pathway antibodies	Hemostasis Pathway Diagram
Immune System Pathway antibodies	Immune System Pathway Diagram
Kinesins Pathway antibodies	Kinesins Pathway Diagram
M Phase Pathway antibodies	M Phase Pathway Diagram
MHC Class II Antigen Presentation Pathway antibodies	MHC Class II Antigen Presentation Pathway Diagram

Diseases associated with anti-KIF20A antibody

Disease Name	Pubmed Publications
Neoplasms Antibodies	>13 publications with KIF20A and Neoplasms
Cell Transformation, Neoplastic Antibodies	>3 publications with KIF20A and Cell Transformation, Neoplastic
Pancreatic Neoplasms Antibodies	>3 publications with KIF20A and Pancreatic Neoplasms
Carcinoma, Hepatocellular Antibodies	>2 publications with KIF20A and Carcinoma, Hepatocellular
Breast Neoplasms Antibodies	>2 publications with KIF20A and Breast Neoplasms
Adenocarcinoma Antibodies	>2 publications with KIF20A and Adenocarcinoma
Necrosis Antibodies	>2 publications with KIF20A and Necrosis
Urinary Bladder Neoplasms Antibodies	>1 publications with KIF20A and Urinary Bladder Neoplasms
Lung Neoplasms Antibodies	>1 publications with KIF20A and Lung Neoplasms
Disease Models, Animal Antibodies	>1 publications with KIF20A and Disease Models, Animal

Organs/Tissues associated with anti-KIF20A antibody

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>5 publications with KIF20A and Blood
Kidney Antibodies	>2 publications with KIF20A and Kidney
Muscle Antibodies	>2 publications with KIF20A and Muscle
Embryonic Tissue Antibodies	>2 publications with KIF20A and Embryonic Tissue
Vascular Antibodies	>1 publications with KIF20A and Vascular
Placenta Antibodies	>1 publications with KIF20A and Placenta
Skin Antibodies	>1 publications with KIF20A and Skin
Brain Antibodies	>1 publications with KIF20A and Brain
Intestine Antibodies	>1 publications with KIF20A and Intestine
Lung Antibodies	>1 publications with KIF20A and Lung